Shamil Sunyaev
机构: Professor of Biomedical Informatics and of Medicine (BWH), Harvard Medical School
主页: harvard.edu
每年引用次数
引用次数
引用: 78,913
H-指数: 89
I10-指数 : 165
出版物: 263
Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation
Amnon Koren , Paz Polak , James Nemesh , Jacob J. Michaelson
American Journal of Human Genetics 91 ( 6) 1033 -1040
179
2012
Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol
Leslie A Lange , Youna Hu , He Zhang , Chenyi Xue
American Journal of Human Genetics 94 ( 2) 233 -245
220
2014
Revisiting mutagenesis at non-B DNA motifs in the human genome
RJ McGinty , SR Sunyaev
Nature structural \& molecular biology 30 ( 4) 417 -424
2023
Universal and lineage-specific trends in protein evolution
EV Koonin , IK Jordan , FA Kondrashov , IA Adzhubei
FEBS JOURNAL 272 79 -79
2005
Molecular Biophysics-How Do Point Amino Acid Substitutions Affect the Protein Structure?
VE Ramensky , PK Vlasov , SR Sunyaev , VG Tumanyan
Biophysics 45 ( 2) 215 -222
1
2000
Mutagenesis at non-B DNA motifs in the human genome: a course correction
RJ McGinty , SR Sunyaev
bioRxiv 2022.02. 08.479604 -2022.02. 08.479604
2022
Epigenome-Wide Association Studies Shows DNA Methylation Association with Excessive Daytime Sleepiness Among African Americans
H Wang , R Barfield , T Sofer , BE Cade
American Thoracic Society A5931 -A5931
2018
Molecular Biophysics-An Approach to the Inverse Folding Problem Based on Multiple Structural Alignment
SR Sunyaev , F Eisenhaber , VG Tumanyan
Biophysics 44 ( 4) 602 -605
1999
In what extent fidopoint mutations affect a protein structure?
VE Ramensky , SR Sunyaev , VG Tumanyan
Find Research Outputs
BE Cade , K Rice , JI Rotter , NA Shah
Genome of the Netherlands Consortium Alzheimer’s Disease Neuroimaging Initiative. 2017. Negative selection in humans and fruit flies involves synergistic epistasis
M Sohail , OA Vakhrusheva , JH Sul , SL Pulit
Science 356 539 -542
4
Prediction of potential GPI-modification sites in proprotein sequences
SR Sunyaev , F Eisenhaber , IV Rodchenkov , B Eisenhaber
Protein Eng 12 387 -394
13
1999
How Do Point Amino Acid Substitutions Affect the Protein Structure?
VE Ramensky , PK Vlasov , SR Sunyaev , VG Tumanyan
Biophysics 45 ( 2) 215 -222
1
2000
Undiagnosed Diseases Network, Brigham and Women’s Hospital FaceBase Project, Brigham Genomic Medicine (BGM): An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery
A Haghighi , JB Krier , A Toth-Petroczy , CA Cassa
NPJ Genom Med 3 ( 21) 30131872 -30131872
4
2018
Phenotypic Variability and mTOR Pathway Gene Aberrations in Familial Tuberous Sclerosis
Winnie S Liang , Shobana Sekar , Sara Nasser , Jonathan Adkins
Journal of pediatric neurology 15 ( 06) 316 -324
2017
A universal trend of amino acid gain and loss in protein evolution (vol 433, pg 633, 2005)
IK Jordan , FA Kondrashov , IA Adzhubei , YI Wolf
Nature 435 ( 7041) 528 -528
2005
AnFiSA: An open-source computational platform for the analysis of sequencing data for rare genetic disease
Michael A Bouzinier , Dmitry Etin , Sergey I Trifonov , VN Evdokimova
Journal of Biomedical Informatics 133 104174 -104174
1
2022
From Statistical Models to Biological Mechanisms of Human Mutation.
S Sunyaev , V Seplyarskiy , R Soldatov , R McGinty
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 60 43 -44
2019
MS/MS background noise filtering; a first step towards robust sequence-similarity identifications
V Surendranath , A Shevchenko , S Sunyaev , P Waridel
MOLECULAR & CELLULAR PROTEOMICS 4 ( 8) S31 -S31
2005
Mutable sites are under stronger negative selection
IA Adzhubey , AS Kondrashov , S Sunyaev