EPEN-18. Oncogenic 3D genome conformations identify novel therapeutic targets in ependymoma
Konstantin Okonechnikov , Aylin Camgöz , Donglim Esther Park , Owen Chapman
Neuro-Oncology 24 ( Supplement\_1) i42 -i42
2022
CRISPR-derived mouse model of North Carolina Macular Dystrophy reveals in trans tissue-specific upregulation of PRDM13
Gavin Arno , Gavin Arno , Verena Heinrich , Katerina Kraft
Investigative Ophthalmology & Visual Science 59 ( 9) 6026 -6026
1
2018
Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A
Pia Kuss , Katerina Kraft , Jürgen Stumm , Daniel Ibrahim
Developmental Biology 385 ( 1) 83 -93
47
2014
EcDNA hubs drive cooperative intermolecular oncogene expression
King L Hung , Kathryn E Yost , Liangqi Xie , Quanming Shi
bioRxiv
65
2020
GENE-02. CHROMOSOME CONFORMATION ANALYSIS OF EPENDYMOMA IDENTIFIES PUTATIVE TUMOR DEPENDENCY GENES ACTIVATED BY DISTAL ONCOGENIC ENHANCERS
Konstantin Okonechnikov , Jens-Martin Hübner , Katerina Kraft , Rocio Acuna Hidalgo
Neuro-oncology 21
2019
GENE-15. TARGETING OF EPENDYMOMA AS INFORMED BY ONCOGENIC 3D GENOME ORGANIZATION
Konstantin Okonechnikov , Jens-Martin Hübner , Owen Chapman , Abhijit Chakraborty
Neuro-oncology 21
2019
Formation of new chromatin domains determines pathogenicity of genomic duplications
Martin Franke , Daniel M. Ibrahim , Guillaume Andrey , Wibke Schwarzer
Nature 538 ( 7624) 265 -269
582
2016
Polymer physics predicts the effects of structural variants on chromatin architecture.
Simona Bianco , Darío G. Lupiáñez , Andrea M. Chiariello , Carlo Annunziatella
Nature Genetics 50 ( 5) 662 -667
97
2018
Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations.
Katerina Kraft , Andreas Magg , Verena Heinrich , Christina Riemenschneider
Nature Cell Biology 21 ( 3) 305 -310
46
2019
Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice
Katerina Kraft , Sinje Geuer , Anja J. Will , Wing Lee Chan
Cell Reports 10 ( 5) 833 -839
130
2015
Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions
Darío G. Lupiáñez , Katerina Kraft , Verena Heinrich , Peter Krawitz
Cell 161 ( 5) 1012 -1025
1,136
2015
Identifying cis Elements for Spatiotemporal Control of Mammalian DNA Replication.
Jiao Sima , Abhijit Chakraborty , Vishnu Dileep , Marco Michalski
Cell 176 ( 4) 816
77
2019
Identification of cis elements for spatio-temporal control of DNA replication
Benoit G. Bruneau , Mats Ljungman , Peter Fraser , Ferhat Ay
bioRxiv 285650
2018
Single-cell multiome of the human retina and deep learning nominate causal variants in complex eye diseases
Sean K Wang , Surag Nair , Rui Li , Katerina Kraft
Cell genomics 2 ( 8)
5
2022
Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis
Robert Schöpflin , Andrea Esposito , Carlo Annunziatella , Simona Bianco
3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma
Konstantin Okonechnikov , Aylin Camgöz , Owen Chapman , Sameena Wani
Nature Communications 14 ( 1) 2300 -2300
3
2023
Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation
Katerina Kraft , Kathryn E Yost , Sedona E Murphy , Andreas Magg
Proceedings of the National Academy of Sciences 119 ( 22) e2201883119 -e2201883119
48
2022
Chromosome conformation analysis of ependymoma tumors identifies putative target genes activated by distal oncogenic enhancers
Konstantin Okonechnikov , Jens-Martin Hübner , Katerina Kraft , Rocio Acuna Hidalgo
Bidirectional epigenetic editing reveals hierarchies in gene regulation
Naomi M Pacalin , Zachary Steinhart , Quanming Shi , Julia A Belk
Nature Biotechnology 1 -14
2024
Xist ribonucleoproteins promote female sex-biased autoimmunity
Diana R Dou , Yanding Zhao , Julia A Belk , Yang Zhao
Cell 187 ( 3) 733 -749. e16
30
2024