Human androgen receptor gene ligand-binding-domain mutations leading to disrupted interaction between the N- and C-terminal domains

J Jaaskelainen , A Deeb , JW Schwabe , NP Mongan
Journal of Molecular Endocrinology 36 ( 2) 361 -368

44
2006
The phantom ligand effect: allosteric control of transcription by the retinoid X receptor.

I G Schulman , C Li , J W Schwabe , R M Evans
web science 11 ( 3) 299 -308

152
1997
The cocrystal structures of two zinc-stabilized DNA-binding domains illustrate different ways of achieving sequence-specific DNA recognition.

J.W.R Schwabe , L. Fairall , L. Chapman , J.T. Finch
Cold Spring Harbor Symposia on Quantitative Biology 58 141 -147

10
1993
Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate.

Rebekah Jukes-Jones , John W R Schwabe , Louise Fairall , Michelle A Hughes
Nature Communications 12 ( 1) 819 -819

2
2021
The topology of chromatin-binding domains in the NuRD deacetylase complex.

Christopher J Millard , Louise Fairall , Timothy J Ragan , Christos G Savva
Nucleic Acids Research 48 ( 22) 12972 -12982

22
2020
An evolving understanding of nuclear receptor coregulator proteins

Christopher J Millard , Peter J Watson , Louise Fairall , John W R Schwabe
Journal of Molecular Endocrinology 51 ( 3)

99
2013
A de novo substitution in BCL11B leads to loss of interaction with transcriptional complexes and craniosynostosis

Jacqueline A C Goos , Walter K Vogel , Hana Mlcochova , Christopher J Millard
Human Molecular Genetics 28 ( 15) 2501 -2513

6
2019
Structural basis for the activation of PPARγ by oxidized fatty acids

Toshimasa Itoh , Louise Fairall , Kush Amin , Yuka Inaba
Nature Structural & Molecular Biology 15 ( 9) 924 -931

307
2008
Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

Jasmeen Oberoi , Louise Fairall , Peter J Watson , Ji-Chun Yang
Nature Structural & Molecular Biology 18 ( 2) 177 -184

116
2011
A specific mutation inTBL1XR1causes Pierpont syndrome

Charlotte A Heinen , Aldo Jongejan , Peter J Watson , Bert Redeker
Journal of Medical Genetics 53 ( 5) 330 -337

37
2016
Complex behaviour

Daniela Rhodes , John W R Schwabe
Nature 352 ( 6335) 478 -479

5
1991
A Dominant-negative Peroxisome Proliferator-activated Receptor γ (PPARγ) Mutant Is a Constitutive Repressor and Inhibits PPARγ-mediated Adipogenesis

Mark Gurnell , John M. Wentworth , Maura Agostini , Maria Adams
Journal of Biological Chemistry 275 ( 8) 5754 -5759

250
2000
Residual activity of mutant androgen receptors explains wolffian duct development in the complete androgen insensitivity syndrome.

Sabine E. Hannema , Ian S. Scott , John Hodapp , Howard Martin
The Journal of Clinical Endocrinology and Metabolism 89 ( 11) 5815 -5822

63
2004
Two de novo mutations in the AR gene cause the complete androgen insensitivity syndrome in a pair of monozygotic twins.

Nigel P. Mongan , Jarmo Jääskeläinen , Katherine Green , John W. Schwabe
The Journal of Clinical Endocrinology and Metabolism 87 ( 3) 1057 -1061

23
2002
Mechanism of corepressor binding and release from nuclear hormone receptors.

L. Nagy , H.-Y. Kao , J. D. Love , C. Li
Genes & Development 13 ( 24) 3209 -3216

376
1999
St John's wort, a herbal antidepressant, activates the steroid X receptor.

JM Wentworth , M Agostini , J Love , JW Schwabe
Journal of Endocrinology 166 ( 3)

210
2000
Activated platelets regulate monocyte tfpi gene expression through the nuclear transcription factor PPAR Gamma

RE Turnbull , KN Sander , PJ Watson , DA Barrett
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 13 466 -466

2015
2002
Human androgen receptor gene ligand-binding-domain mutations leading to disrupted interaction between the N- and C-terminal domains

J Jaaskelainen , A Deeb , JW Schwabe , NP Mongan
Journal of Molecular Endocrinology 36 ( 2) 361 -368

44
2006
A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death

Laura S. Dickens , Robert S. Boyd , Rebekah Jukes-Jones , Michelle A. Hughes
Molecular Cell 47 ( 2) 291 -305

214
2012