Model systems with GPCRs embedded in multicomponent membranes

Ramon Guixà-González , Jana Selent , Matti Javanainen , Hector Martinez-Seara

2015
Martini 3: a general purpose force field for coarse-grained molecular dynamics.

Sebastian Thallmair , Sebastian Thallmair , D. Peter Tieleman , Valentina Corradi
Nature Methods 18 ( 4) 382 -388

295
2021
Enzymatic Oxidation of Cholesterol: Properties and Functional Effects of Cholestenone in Cell Membranes

Maarit Neuvonen , Moutusi Manna , Sini Mokkila , Matti Javanainen
PLoS ONE 9 ( 8) e103743

36
2014
Arginine-rich cell-penetrating peptides induce membrane multilamellarity and subsequently enter via formation of a fusion pore.

Christoph Allolio , Aniket Magarkar , Piotr Jurkiewicz , Katarína Baxová
Proceedings of the National Academy of Sciences of the United States of America 115 ( 47) 11923 -11928

55
2018
Protocol to Avoid Possible Artifacts in Atomistic Simulation of GPCR Proteins whose Crystal Structure is Heavily Engineered

Moutusi Manna , Waldemar Kulig , Matti Javanainen , Joona Tynkkynen
Biophysical Journal 110 ( 3)

2016
Structural Effects of Cation Binding to DPPC Monolayers.

Matti Javanainen , Wei Hua , Ondrej Tichacek , Pauline Delcroix
Langmuir 36 ( 50) 15258 -15269

1
2020
Multiscale Simulations of Biological Membranes: The Challenge To Understand Biological Phenomena in a Living Substance.

Giray Enkavi , Matti Javanainen , Waldemar Kulig , Tomasz Róg
Chemical Reviews 119 ( 9) 5607 -5774

188
2019
Understanding the Functional Properties of Lipid Heterogeneity in Pulmonary Surfactant Monolayers at the Atomistic Level.

Juho Liekkinen , Berta de Santos Moreno , Riku O. Paananen , Ilpo Vattulainen
Frontiers in Cell and Developmental Biology 8 581016

2020
Toward Atomistic Resolution Structure of Phosphatidylcholine Headgroup and Glycerol Backbone at Different Ambient Conditions

Alexandru Botan , Fernando Favela-Rosales , Patrick F. J. Fuchs , Matti Javanainen
Journal of Physical Chemistry B 119 ( 49) 15075 -15088

74
2015
How well does cholesteryl hemisuccinate mimic cholesterol in saturated phospholipid bilayers

Waldemar Kulig , Joona Tynkkynen , Matti Javanainen , Moutusi Manna
Journal of Molecular Modeling 20 ( 2) 2121

50
2014
Cationic Au Nanoparticle Binding with Plasma Membrane-like Lipid Bilayers: Potential Mechanism for Spontaneous Permeation to Cells Revealed by Atomistic Simulations

Elena Heikkilä , Hector Martinez-Seara , Andrey A. Gurtovenko , Matti Javanainen
Journal of Physical Chemistry C 118 ( 20) 11131 -11141

50
2014
On Atomistic Models for Molecular Oxygen.

Matti Javanainen , Ilpo Vattulainen , Luca Monticelli
Journal of Physical Chemistry B 121 ( 3) 518 -528

12
2017
Flip-Flops of Lipids in the Absence of Atp: Role of Membrane Proteins

Tuomo Nieminen , Matti Javanainen , Reinis Danne , Tomasz Rog
Biophysical Journal 106 ( 2) 705a

1
2014
What Happens for Sterol Dynamics When Cholesterol is Enzymatically Oxidized?

Moutusi Manna , Sini Mokkila , Matti Javanainen , Tomasz Rog
Biophysical Journal 106 ( 2) 704a

2014
Characterisation of Coexisting Liquid Phases in Mixtures of Dipalmitoylphosphatidylcholine and Cholesterol

Matti Javanainen , Hector Martinez-Seara , Ilpo Vattulainen
Biophysical Journal 106 ( 2) 709a -710a

2014
Dynamics and energetics of the mammalian phosphatidylinositol transfer protein phospholipid exchange cycle

Aby Grabon , Adam Orłowski , Ashutosh Tripathi , Joni Vuorio
Journal of Biological Chemistry 292 ( 35) 14438 -14455

14
2017
Molecular electrometer and binding of cations to phospholipid bilayers

Andrea Catte , Mykhailo Girych , Matti Javanainen , Claire Loison
Physical Chemistry Chemical Physics 18 ( 47) 32560 -32569

32
2016
Protein Crowding in Lipid Bilayers Gives Rise to Non-Gaussian Anomalous Lateral Diffusion of Phospholipids and Proteins

Jae-Hyung Jeon , Matti Javanainen , Hector Martinez-Seara , Ralf Metzler
Physical Review X 6 ( 2) 021006

138
2016
Universal Method for Embedding Proteins into Complex Lipid Bilayers for Molecular Dynamics Simulations.

Matti Javanainen
Journal of Chemical Theory and Computation 10 ( 6) 2577 -2582

41
2014