Nigel Scrutton
机构: Professor of Enzymology, Manchester Institute of Biotechnology (MIB) and School of Chemistry
主页: manchester.ac.uk
每年引用次数
引用次数
引用: 22,348
H-指数: 77
I10-指数 : 374
出版物: 612
Pentaerythritol tetranitrate reductase: reaction with NADPH, steroids, 2-cyclohexenone, nitroesters and nitroaromatic explosives
Nigel Scrutton , RJ Harris , SK Chapman , AW Munro
In: Chapman SK, Perham RN, Scrutton NS, editor(s). Flavins and Flavoproteins. Weber; 2002. p. 247-252. 247 -252
2002
Probing of small molecules and proteins low frequency vibrations using Terahertz radiation at SRS Daresbury laboratory
Fersi , Gardner , Surman , Scutliffe
international conference on infrared, millimeter, and terahertz waves 393 -394
2007
Purification and characterization of glutathione reductase encoded by a cloned and over-expressed gene in Escherichia coli.
N S Scrutton , A Berry , R N Perham
Biochemical Journal 245 ( 3) 875 -880
49
1987
Altering kinetic mechanism and enzyme stability by mutagenesis of the dimer interface of glutathione reductase
A Bashir , R N Perham , N S Scrutton , A Berry
Biochemical Journal 312 ( 2) 527 -533
24
1995
Excited State Dynamics Can Be Used to Probe Donor-Acceptor Distances for H-Tunneling Reactions Catalyzed by Flavoproteins
Samantha J.O. Hardman , Christopher R. Pudney , Sam Hay , Nigel S. Scrutton
Biophysical Journal 105 ( 11) 2549 -2558
15
2013
Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation
Sam Hay , Christopher Pudney , Parvinder Hothi , Linus O. Johannissen
Biochemical Society Transactions 36 ( 1) 16 -21
19
2008
Enzyme mechanisms: fast reaction and computational approaches.
Andrew W. Munro , Nigel S. Scrutton
Biochemical Society Transactions 37 ( 2) 333 -335
2
2009
Conformational changes in the catalytic cycle of protochlorophyllide oxidoreductase: what lessons can be learnt from dihydrofolate reductase?
Derren J. Heyes , Nigel S. Scrutton
Biochemical Society Transactions 37 ( 2) 354 -357
9
2009
Time-resolved studies of radical pairs
Jonathan R. Woodward , Timothy J. Foster , Alex R. Jones , Adrian T. Salaoru
Biochemical Society Transactions 37 ( 2) 358 -362
16
2009
SYNBIOCHEM - A SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals.
Pablo Carbonell , Andrew Currin , Mark Dunstan , Donal Fellows
Biochemical Society Transactions 44 ( 3) 675 -677
6
2016
Comprehensive Analysis of the Green-to-Blue Photoconversion of Full-Length Cyanobacteriochrome Tlr0924
Samantha J.O. Hardman , Anna F.E. Hauck , Ian P. Clark , Derren J. Heyes
Biophysical Journal 107 ( 9) 2195 -2203
9
2014
Trp359 regulates flavin thermodynamics and coenzyme selectivity in Mycobacterium tuberculosis FprA
Rajasekhar Neeli , Muna Sabri , Kirsty J. McLean , Adrian J. Dunford
Biochemical Journal 411 ( 3) 563 -570
5
2008
Characterization of coenzyme binding and selectivity determinants in Mycobacterium tuberculosis flavoprotein reductase A: analysis of Arg199 and Arg200 mutants at the NADP(H) 2′-phosphate binding site
Muna Sabri , Adrian J. Dunford , Kirsty J. McLean , Rajasekhar Neeli
Biochemical Journal 417 ( 1) 103 -114
8
2009
Kinetic isotope effects and ligand binding in PQQ-dependent methanol dehydrogenase
Parvinder HOTHI , Michael J. SUTCLIFFE , Nigel S. SCRUTTON
Biochemical Journal 388 ( 1) 123 -133
15
2005
SYNBIOCHEM Synthetic Biology Research Centre, Manchester - A UK foundry for fine and speciality chemicals production
Le Feuvre RA , Carbonell P , Currin A , Dunstan M
Synthetic and Systems Biotechnology 1 ( 4) 271 -275
7
2016
NADPH generation in Aspergillus nidulans: is the mannitol cycle involved?
M. SINGH , N. S. SCRUTTON , M. C. SCRUTTON
Microbiology 134 ( 3) 643 -654
38
1988
Homodimeric and expanded behaviour of trimethylamine dehydrogenase in solution at different temperatures
Helmut C�lfen , StephenE. Harding , EmmaK. Wilson , LenC. Packman
European Biophysics Journal 24 ( 3) 159 -164
7
1996
Asymmetric Reduction of Activated Alkenes by Pentaerythritol Tetranitrate Reductase: Specificity and Control of Stereochemical Outcome by Reaction Optimisation
Anna Fryszkowska , Helen Toogood , Michiyo Sakuma , Johnâ
M. Gardiner
Advanced Synthesis & Catalysis 351 ( 17) 2976 -2990
99
2009
Recombinant two-iron rubredoxin of Pseudomonas oleovorans: overexpression, purification and characterization by optical, CD and 113Cd NMR spectroscopies
Ho Joon LEE , Lu-Yun LIAN , S. Nigel SCRUTTON
Biochemical Journal 328 ( 1) 131 -136
17
1997
Kinetics of CO binding and CO photodissociation in Pseudomonas stutzeri cd1 nitrite reductase: probing the role of extended N-termini in fast structural relaxation upon CO photodissociation
E.K. WILSON , A. BELLELLI , F. CUTRUZZOLÀ , W.G. ZUMFT
Biochemical Journal 356 ( 3) 911 -911
8
2001