Antonina Roll-Mecak
机构: Senior Investigator and Chief, Cell Biology and Biophysics Unit
主页: nih.gov
每年引用次数
引用次数
引用: 5,296
H-指数: 37
I10-指数 : 45
出版物: 90
Universal translation initiation factor IF2/eIF5B.
TE Dever , A Roll-Mecak , SK Choi , JH Lee
Cold Spring Harbor Symposia on Quantitative Biology 66 417 -424
11
2001
A conserved GTP hydrolysis step in translation initiation: Structural and functional studies of universal translation initiation factor IF2/eIF5B
Antonina Ilaria Roll-Mecak
The Rockefeller University
2002
α-tubulin tail modifications regulate microtubule stability through selective effector recruitment, not changes in intrinsic polymer dynamics
Nikita Gudimchuk , Nikita Gudimchuk , Antonina Roll-Mecak , Ilya Kovalenko
Developmental Cell
33
2021
An allosteric network in spastin couples multiple activities required for microtubule severing.
Colby R. Sandate , Agnieszka Szyk , Elena A. Zehr , Gabriel C. Lander
Nature Structural & Molecular Biology 26 ( 8) 671 -678
18
2019
Author Correction: An allosteric network in spastin couples multiple activities required for microtubule severing.
Colby R. Sandate , Agnieszka Szyk , Elena A. Zehr , Gabriel C. Lander
Nature Structural & Molecular Biology 27 ( 4) 400 -400
2020
Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Kishore K. Mahalingan , E. Keith Keenan , Madeleine Strickland , Yan Li
Nature Structural & Molecular Biology 27 ( 9) 802 -813
6
2020
Tubulin tyrosine ligase and stathmin compete for tubulin binding in vitro.
Agnieszka Szyk , Grzegorz Piszczek , Antonina Roll-Mecak
Journal of Molecular Biology 425 ( 14) 2412 -2414
11
2013
Microtubule dynamics: 50 years after the discovery of tubulin and still going strong.
Gaia Pigino , Antonina Roll-Mecak
Molecular Biology of the Cell 28 ( 6) 705 -706
2017
Tubulin isoform composition tunes microtubule dynamics
Annapurna Vemu , Joseph Atherton , Jeffrey O. Spector , Carolyn A. Moores
Molecular Biology of the Cell 28 ( 25) 3564 -3572
80
2017
Crystal Structures of Tubulin Acetyltransferase Reveal a Conserved Catalytic Core and the Plasticity of the Essential N Terminus
Vasilisa Kormendi , Agnieszka Szyk , Grzegorz Piszczek , Antonina Roll-Mecak
Journal of Biological Chemistry 287 ( 50) 41569 -41575
30
2012
Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin
Annapurna Vemu , Joseph Atherton , Jeffrey O. Spector , Agnieszka Szyk
Journal of Biological Chemistry 291 ( 25) 12907 -12915
99
2016
Mechanisms of microtubule dynamics and force generation examined with computational modeling and electron cryotomography.
Nikita B. Gudimchuk , Evgeni V. Ulyanov , Eileen O’Toole , Cynthia L. Page
Nature Communications 11 ( 1) 3765 -3765
49
2020
Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity.
Byung-Sik Shin , David Maag , Antonina Roll-Mecak , M.Shamsul Arefin
Cell 111 ( 7) 1015 -1025
97
2002
Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin.
Antonina Roll-Mecak , Ronald D. Vale
Nature 451 ( 7176) 363 -367
232
2008
Intrinsically disordered tubulin tails: complex tuners of microtubule functions?
Antonina Roll-Mecak
Seminars in Cell & Developmental Biology 37 11 -19
67
2015
The Tubulin Code in Microtubule Dynamics and Information Encoding.
Antonina Roll-Mecak
Developmental Cell 54 ( 1) 7 -20
120
2020
Physical and functional interaction between the eukaryotic orthologs of prokaryotic translation initiation factors IF1 and IF2.
Sang Ki Choi , DeAnne S. Olsen , Antonina Roll-Mecak , Agnes Martung
Molecular and Cellular Biology 20 ( 19) 7183 -7191
70
2000
Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules
Elena A. Zehr , Agnieszka Szyk , Ewa Szczesna , Antonina Roll-Mecak
Developmental Cell 52 ( 1)
14
2020
The chemical complexity of cellular microtubules: tubulin post-translational modification enzymes and their roles in tuning microtubule functions
Christopher P. Garnham , Antonina Roll-Mecak
Cytoskeleton 69 ( 7) 442 -463
114
2012
Microtubule chemical complexity: mechanism of tubulin modification enzymes
Antonina Roll-Mecak , Agnieszka Szyk , Vasilisa Kormendi
Acta Crystallographica Section A 70
2014