引用次数
引用: 44,659
H-指数: 104
I10-指数 : 218
出版物: 343
Spatial Separation of Plk1 Phosphorylation and Activity
Wytse Bruinsma , Melinda Aprelia , Jolanda Kool , Libor Macurek
Frontiers in Oncology 5 132 -132
24
2015
Fundamentele aspecten van kanker
R.H. Medema , J.H.J.M. van Krieken
Velde, C.J.H. van de (ed.), Leerboek oncologie 3 -28
2017
Interaction between the p21ras GTPase activating protein and the insulin receptor
G.J. Pronk , R.H. Medema , B.M. Burgering , R Clark
Journal of Biological Chemistry 267 ( 33) 24058 -24063
41
1992
Life in the (Pluripotent) Fast Lane: Cdk1 Preserves the Epigenome to Maintain Pluripotency
J.A. Raaijmakers , R.H. Medema
Molecular Cell 78 ( 3) 374 -375
2020
Relation between the insulin receptor number in cells, autophosphorylation and insulin-stimulated Ras.GTP formation.
A.P. Osterop , R.H. Medema , J.L. Bos , G.C. vd Zon
Journal of Biological Chemistry 267 ( 21) 14647 -14653
53
1992
Insulin-induced p21ras activation does not require protein kinase C, but a protein sensitive to phenylarsine oxide.
R.H. Medema , B.M. Burgering , J.L. Bos
Journal of Biological Chemistry 266 ( 31) 21186 -21189
39
1991
Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model
A.R.R. Maia , J. de Man , U. Boon , A. Janssen
Annals of Oncology 26 ( 10) 2180 -2192
96
2015
Knockdown of Polo-like kinase-1 prevents centrosome separation and leads to a spindle checkpoint arrest.
Matm van Vugt , RH Medema
Cytoskeleton 54 ( 2) 189 -189
2003
Synthetic lethal genetic interactions in spindle assembly checkpoint (SAC)-deficient human cells.
JA Raaijmakers , R Van Heesbeen , V Blomen , L Janssen
MOLECULAR BIOLOGY OF THE CELL 27
2016
Wip1 phosphatase is associated with chromatin and dephosphorylates γH2AX to promote checkpoint inhibition
L Macůrek , A Lindqvist , O Voets , J Kool
Oncogene 29 ( 15) 2281 -2291
182
2010
Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for APC/Cdc20 activation and initiation of cytokinesis
MA Van Vugt , BC Van De Weerdt , G Vader , H Janssen
J. Biol. Chem 279 36841 -36854
6
2004
Molecular basis underlying resistance against Mps1/TTK inhibitors.
A Koch , RH Medema
MOLECULAR BIOLOGY OF THE CELL 25
2014
Cdk4/6-dependent activation of FOXM1 controls recovery from DNA damage in G1
IA Shaltiel , M Aprelia , A Llopis , EE Voest
MOLECULAR BIOLOGY OF THE CELL 25
2014
Hypersensitivity to DNA double strand breaks in late G2 protects against checkpoint adaptation
L Krenning , FM Feringa , RH Medema
MOLECULAR BIOLOGY OF THE CELL 25
2014
HC StratoMineR: A web-based data mining tool for the rapid analysis of high content data sets.
WA Omta , RG van Heesbeen , RJ Pagliero , D Lelieveld
MOLECULAR BIOLOGY OF THE CELL 25
2014
Consequences of a prolonged mitosis.
L Krenning , RH Medema
MOLECULAR BIOLOGY OF THE CELL 22
2011
Succesful donor leukocyte infusions (DLI) for relapsed leukemia after bone marrow transplantation abrogate tolerance by inducing a skewing in the anti-leukemic cytokine response profile.
BL Herpers , RH Medema , G Rijksen , GJ Boonen
BLOOD 98 ( 11) 325B -325B
2001
Negative growth regulation of leukemic T cells by T cell receptor activation is associated with down-regulation of cyclin D3.
GJJC Boonen , G Rijksen , LF Verdonck , RH Medema
BLOOD 92 ( 10) 192B -192B
1998
Growth control in normal and leukemic T lymphocytes
GJJC Boonen , G Rijksen , LF Verdonck , RH Medema
BRITISH JOURNAL OF HAEMATOLOGY 102 ( 1) 31 -31
1998
Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids
Jeanine M.L. Roodhart , Laura G.M. Daenen , Edwin C.A. Stigter , Henk-Jan Prins
Cancer Cell 20 ( 3) 370 -383
226
2011