Brad S. Rothberg
机构: Professor of Medical Genetics & Molecular Biochemistry, Temple University School of Medicine
每年引用次数
引用次数
引用: 3,918
H-指数: 26
I10-指数 : 40
出版物: 78
Investigating single-channel gating mechanisms through analysis of two-dimensional dwell-time distributions.
Brad Srothberg , Karl L. Magleby
Methods in Enzymology 293 437 -456
6
1998
Crystal Structure of a Ba2+-Bound Gating Ring Reveals Elementary Steps in RCK Domain Activation
Frank J. Smith , Victor P.T. Pau , Gino Cingolani , Brad S. Rothberg
Structure 20 ( 12) 2038 -2047
13
2012
MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.
Karthik Mallilankaraman , Patrick Doonan , César Cárdenas , Harish C. Chandramoorthy
Cell 151 ( 3) 630 -644
599
2012
High Ca2+ concentrations induce a low activity mode and reveal Ca2(+)-independent long shut intervals in BK channels from rat muscle.
B S Rothberg , R A Bello , L Song , K L Magleby
The Journal of Physiology 493 ( 3) 673 -689
36
1996
Mechanism of
Fen Wang , XU Bing , Kun-feng Zhang , Mao-rui Yang
10
2006
Cooperative allosteric gating for voltage-and Ca2+-activation of large conductance Ca2+-activated KC (BK) channels.
KL Magleby , BS Rothberg
BIOPHYSICAL JOURNAL 80 ( 1) 222A -222A
6
2001
Voltage-dependent steps in the gating of single BK channels
BS Rothberg , KL Magleby
Biophys. J 76 A333 -A333
2
1999
Analysis of the calcium-dependent gating of single BK channels with 2-D dwell-time distributions suggests additional gating steps.
BS Rothberg , KL Magleby
BIOPHYSICAL JOURNAL 74 ( 2) A240 -A240
1
1998
Gating mechanisms for single BK channels determined using Q-matrix fitting of two-dimensional dwell-time distributions
BS Rothberg , RA Bello , KL Magleby
BIOPHYSICAL JOURNAL 72 ( 2) TUPM2 -TUPM2
1
1997
A two-tiered allosteric mechanism describes both the calcium-and voltage-dependent gating of single calcium-activated K channels
BS Rothberg , KL Magleby
BIOPHYSICAL JOURNAL 78 ( 1) 92A -92A
2000
CORRECTION The Journal of General Physiology
BS Rothberg , KL Magleby
The Journal of General Physiology 114 ( 1) 93 -124
1999
Kinetic schemes derived form Q-matrix fitting of two-dimensional dwell-time distributions suggest gating mechanisms for dSlo and mSlo BK channels.
BL Moss , SD Silberberg , BS Rothberg , RA Bello
BIOPHYSICAL JOURNAL 72 ( 2) MPO23 -MPO23
1997
Hidden components and hidden dependencies determined from two-dimensional (2-D) dwell-time distributions from single BK channels in rat skeletal muscle
KL Magleby , RA Bello , BS Rothberg
BIOPHYSICAL JOURNAL 72 ( 2) TUPM1 -TUPM1
1997
High calcium induces a low activity mode and reveals calcium-independent long shut intervals in BK channels.
BS Rothberg , RA Bello , L Song , KL Magleby
BIOPHYSICAL JOURNAL 70 ( 2) TUAM2 -TUAM2
1996
Gated access to the pore of a hyperpolarization-activated (Ih) cation channel
BS Rothberg , P Phale , KS Shin , G Yellen
BIOPHYSICAL JOURNAL 80 ( 1) 16A -16A
2001
Mechanism Of Increased Bk Channel Activation From A Channel Mutation That Causes Epilepsy
Bin Wang , Brad S. Rothberg , Robert Brenner
Biophysical Journal 96 ( 3)
2009
Molecular Architecture and Divalent Cation Activation of TvoK, a Prokaryotic Potassium Channel
Lyubov V. Parfenova , Karin Abarca-Heidemann , Brittany M. Crane , Brad S. Rothberg
Journal of Biological Chemistry 282 ( 33) 24302 -24309
13
2007
Sterol hindrance of Orai activation.
Robert Hooper , Brad S. Rothberg , Jonathan Soboloff
Science Signaling 9 ( 418)
1
2016
A slick, slack pathway through the pore.
Brad S. Rothberg
The Journal of Physiology 595 ( 7) 2337 -2338
1
2017
Blocker state dependence and trapping in hyperpolarization-activated cation channels: evidence for an intracellular activation gate.
Ki Soon Shin , Brad S. Rothberg , Gary Yellen
The Journal of General Physiology 117 ( 2) 91 -102
153
2001