Gerard Drewes
机构: Cellzome/GlaxoSmithKline R&D
每年引用次数
引用次数
引用: 31,491
H-指数: 61
I10-指数 : 108
出版物: 174
Discovery of small-molecule compounds targeting c-MYC using a novel cell-based screen
Biju Mangatt , Anthony D Pietra , Anna Waszkiewicz , Jon-Paul Jaworski
Cancer Research 78 ( 13_Supplement) 2919 -2919
2018
Interchain and intrachain crosslinking of actin thiols by a bifunctional thiol reagent
Heinz Faulstich , Daniela Heintz , Gerard Drewes
FEBS Letters 302 ( 3) 201 -205
11
1992
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immuno-inflammation.
Omer Gilan , Inmaculada Rioja , Kathy Knezevic , Matthew J Bell
Science 368 ( 6489) 387 -394
219
2020
Probing the phalloidin binding site of actin
Heinz Faulstich , Susanne Zobeley , Daniela Heintz , Gerard Drewes
FEBS Letters 318 ( 3) 218 -222
33
1993
Chemoproteomic approaches to drug target identification and drug profiling
Marcus Bantscheff , Gerard Drewes
Bioorganic & Medicinal Chemistry 20 ( 6) 1973 -1978
75
2012
Biological plasticity rescues target activity in CRISPR knock outs.
Arne H Smits , Frederik Ziebell , Gerard Joberty , Nico Zinn
Nature Methods 16 ( 11) 1087 -1093
77
2019
Collaborative approaches for Target ID in neglected diseases: identifying new antimalarial targets
Maria Jose Lafuente , Sonja Guidelli-Disse , Carolyn Selenski , Joel Lelievre
Malaria Journal 13 ( 1) 54
2014
Identification of Plasmodium PI4 kinase as target of MMV390048 by chemoproteomics
Sonja Ghidelli-Disse , Maria Jose Lafuente-Monasterio , David Waterson , Michael Witty
Malaria Journal 13 ( 1) 38
16
2014
Click chemistry enables preclinical evaluation of targeted epigenetic therapies
Dean S. Tyler , Johanna Vappiani , Tatiana Cañeque , Enid Y. N. Lam
Science 356 ( 6345) 1397 -1401
110
2017
Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites.
Alexios N. Matralis , Adnan Malik , Maria Penzo , Inmaculada Moreno
Journal of Medicinal Chemistry 62 ( 20) 9217 -9235
11
2019
New Allosteric Inhibitors of Mutant IDH1 in Acute Myeloid Leukemia
Ujunwa Cynthia Okoye-Okafor , Boris Bartholdy , Jessy Cartier , Enoch Gao
Blood 126 ( 23) 787 -787
1
2015
Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics
Armin Haupt , Gerard Joberty , Marcus Bantscheff , Holger Fröhlich
BMC Cancer 12 ( 1) 38 -38
36
2012
MARK, a Novel Family of Protein Kinases That Phosphorylate Microtubule-Associated Proteins and Trigger Microtubule Disruption
Gerard Drewes , Andreas Ebneth , Ute Preuss , Eva-Maria Mandelkow
Cell 89 ( 2) 297 -308
722
1997
Pathway proteomics and chemical proteomics team up in drug discovery.
Carsten Hopf , Marcus Bantscheff , Gerard Drewes
Neurodegenerative Diseases 4 270 -280
13
2007
Proteome survey reveals modularity of the yeast cell machinery
Anne-Claude Gavin , Patrick Aloy , Paola Grandi , Roland Krause
Nature 440 ( 7084) 631 -636
3,013
2006
Cell Penetrant Inhibitors of the Kdm4 and Kdm5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-Pyridine Carboxylate Derivatives.
Susan M Westaway , Alex GS Preston , Michael D Barker , Fiona Brown
Journal of Medicinal Chemistry 59 ( 4) 1357 -1369
48
2016
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.
Susan M Westaway , Alex GS Preston , Michael D Barker , Fiona Brown
Journal of Medicinal Chemistry 59 ( 4) 1370 -1387
46
2016
The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold
Elena Sandoval , María José Lafuente-Monasterio , Maria J Almela , Pablo Castaneda
Journal of Medicinal Chemistry 60 ( 16) 6880 -6896
4
2017
Discovery of a Highly Selective Tankyrase Inhibitor Displaying Growth Inhibition Effects against a Diverse Range of Tumor Derived Cell Lines.
Douglas W. Thomson , Anne J. Wagner , Marcus Bantscheff , R. Edward Benson
Journal of Medicinal Chemistry 60 ( 13) 5455 -5471
17
2017
O4-04-02: Identification of proteins that form complexes with tau in mouse brain
Diederik Moechars , Joris Winderickx , Frank Fischer , Melanie Jundt
Alzheimer's & Dementia 6 ( 4) S155 -S155
2010
Marcus Bantscheff Bernhard Kuster Mikhail Savitski Friedrich Reinhard Susanne Illenberger Rab Prinjha Yann Abraham Isabelle Becher Holger Wille Wolfgang Huber Nico Zinn David Harold Drewry Par Nordlund Daniel Martinez Molina Susan Klaeger kouzarides Johan Van Lint Andrew J Bannister Yanmin Chen Qingjie Wang