Manish Shah
机构: Albany College of Pharmacy and Health Sciences
每年引用次数
引用次数
引用: 882
H-指数: 16
I10-指数 : 21
出版物: 25
The 1.8 Å Crystal Structure of PA2412, an MbtH-like Protein from the Pyoverdine Cluster of Pseudomonas aeruginosa
Eric J. Drake , Jin Cao , Jun Qu , Manish B. Shah
Journal of Biological Chemistry 282 ( 28) 20425 -20434
48
2007
Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4
Jyothi C. Talakad , Manish B. Shah , Gregory S. Walker , Cathie Xiang
Drug Metabolism and Disposition 39 ( 3) 539 -550
17
2011
A Structural Snapshot of CYP2B4 in Complex with Paroxetine Provides Insights into Ligand Binding and Clusters of Conformational States
Manish B. Shah , Irina Kufareva , Jaime Pascual , Qinghai Zhang
Journal of Pharmacology and Experimental Therapeutics 346 ( 1) 113 -120
12
2013
Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9
Keiko Maekawa , Motoyasu Adachi , Yumiko Matsuzawa , Qinghai Zhang
Biochemistry 56 ( 41) 5476 -5480
25
2017
Structural and thermodynamic basis of (+)-α-pinene binding to human cytochrome P450 2B6.
P. Ross Wilderman , Manish B. Shah , Hyun-Hee Jang , C. David Stout
Journal of the American Chemical Society 135 ( 28) 10433 -10440
27
2013
Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations.
Jingbao Liu , Manish B. Shah , Qinghai Zhang , C. David Stout
Biochemistry 55 ( 13) 1997 -2007
7
2016
Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity.
Manish B. Shah , Jingbao Liu , Qinghai Zhang , C. David Stout
ACS Chemical Biology 12 ( 5) 1204 -1210
19
2017
Structure of Cytochrome P450 2C9*2 in Complex with Losartan: Insights into the Effect of Genetic Polymorphism.
Sonia J. Parikh , Chiara M. Evans , Juliet O. Obi , Qinghai Zhang
Molecular Pharmacology 98 ( 5) 529 -539
2020
Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry
Manish B. Shah , Hyun-Hee Jang , P. Ross Wilderman , David Lee
Biophysical Chemistry 216 1 -8
8
2016
Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains
Qinghai Zhang , C. David Stout , James R. Halpert , Manish B. Shah
Molecular Pharmacology 80 ( 6) 1047 -1055
35
2011
Structural and Biophysical Characterization of Human Cytochromes P450 2B6 and 2A6 Bound to Volatile Hydrocarbons: Analysis and Comparison.
Manish B. Shah , P. Ross Wilderman , Jingbao Liu , Hyun-Hee Jang
Molecular Pharmacology 87 ( 4) 649 -659
5
2015
Conformational Adaptation of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 Revealed Upon Binding Multiple Amlodipine Molecules
Manish B. Shah , P. Ross Wilderman , Jaime Pascual , Qinghai Zhang
Biochemistry 51 ( 37) 7225 -7238
51
2012
Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray Crystallography
P. Ross Wilderman , Manish B. Shah , Tong Liu , Sheng Li
Journal of Biological Chemistry 285 ( 49) 38602 -38611
48
2010
X-ray crystal structure of the cytochrome P450 2B4 active site mutant F297A in complex with clopidogrel: insights into compensatory rearrangements of the binding pocket.
Manish B. Shah , Hyun-Hee Jang , Qinghai Zhang , C. David Stout
Archives of Biochemistry and Biophysics 530 ( 2) 64 -72
6
2013
Four decades of cytochrome P450 2B research: from protein adducts to protein structures and beyond
Arthur G Roberts , Jeffrey C Stevens , Grazyna D Szklarz , Emily E Scott
Drug Metabolism and Disposition 51 ( 1) 111 -122
1
2023
The 2.1 Å crystal structure of an acyl‐CoA synthetase from Methanosarcina acetivorans reveals an alternate acyl‐binding pocket for small branched acyl substrates
Manish B Shah , Cheryl Ingram‐Smith , Leroy L Cooper , Jun Qu
Proteins: Structure, Function, and Bioinformatics 77 ( 3) 685 -698
27
2009
Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl) imidazole at 2.0-Å resolution
Sean C Gay , Manish B Shah , Jyothi C Talakad , Keiko Maekawa
Molecular pharmacology 77 ( 4) 529 -538
105
2010
Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism.
Manish B Shah , Jingbao Liu , Lu Huo , Qinghai Zhang
Molecular Pharmacology 89 ( 4) 435 -445
12
2016
Insights into the genetic variations of human cytochrome P450 2C9: structural analysis, characterization and comparison
Sonia J Parikh , Sumit Kamat , Margaret Phillips , Samuel P Boyson
International Journal of Molecular Sciences 22 ( 19) 10206 -10206
11
2021
Inhibition of CYP2C8 by acyl glucuronides of gemfibrozil and clopidogrel: pharmacological significance, progress and challenges
Manish B Shah
Biomolecules 12 ( 9) 1218 -1218
4
2022