Philip Cole
机构: Professor, Harvard Medical School and Brigham and Women's Hospital
主页: harvard.edu
每年引用次数
引用次数
引用: 36,080
H-指数: 95
I10-指数 : 246
出版物: 396
Chemical approaches to protein phosphorylation
P A Cole
Cellular & Molecular Biology Letters 06
2001
The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.
G Giotopoulos , W-I Chan , S J Horton , D Ruau
Oncogene 35 ( 3) 279 -289
44
2016
Evaluation of the catalytic mechanism of recombinant human Csk (C-terminal Src kinase) using nucleotide analogs and viscosity effects.
P A Cole , P Burn , B Takacs , C T Walsh
Journal of Biological Chemistry 269 ( 49) 30880 -30887
121
1994
Conversion of 19-oxo[2β-2H]androgens into oestrogens by human placental aromatase. An unexpected stereochemical outcome
P A Cole , C H Robinson
Biochemical Journal 268 ( 3) 553 -561
42
1990
Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation
Y Zhang , S Dayalan Naidu , K Samarasinghe , G C Van Hecke
British Journal of Cancer 110 ( 1) 71 -82
24
2014
Acetylation of RNA polymerase II regulates growth-factor-induced gene transcription in mammalian cells.
Sebastian Schröder , Eva Herker , Friederike Itzen , Daniel He
Molecular Cell 52 ( 3) 314 -324
77
2013
Development of Neh2-Luciferase Reporter and Its Application for High Throughput Screening and Real-Time Monitoring of Nrf2 Activators
Natalya A. Smirnova , Renee E. Haskew-Layton , Manuela Basso , Dmitry M. Hushpulian
Chemistry & Biology 18 ( 6) 752 -765
80
2011
HSF1-dependent upregulation of Hsp70 by sulfhydryl-reactive inducers of the KEAP1/NRF2/ARE pathway.
Ying Zhang , Young-Hoon Ahn , Ivor J. Benjamin , Tadashi Honda
Chemistry & Biology 18 ( 11) 1355 -1361
108
2011
Reader's block
Sean D. Taverna , PhiliP A. Cole
Nature 468 ( 7327) 1050 -1051
7
2010
Epigenetic Silencing of BMP6 by the SIN3A–HDAC1/2 Repressor Complex Drives Melanoma Metastasis via FAM83G/PAWS1
Dongkook Min , Jaemin Byun , Eun-Joon Lee , Abdul A Khan
Molecular Cancer Research 20 ( 2) 217 -230
6
2022
A chemical portrait of and inhibitor development for cytochrome P-450 aromatase
Philip Arthur Cole
The Johns Hopkins University
1991
A FACILE SYNTHETIC METHOD FOR PRODUCING STEROIDAL 4-ENE-3-ONE SYSTEMS
PA COLE , WE CHILDERS , E SAFI , CH ROBINSON
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 197 114 -MEDI
1989
19-HYDROPEROXIDE ANDROSTENEDIONE DERIVATIVES-TRANSITION-STATE MODELS FOR PLACENTAL AROMATASE
PA COLE , CH ROBINSON
FEDERATION PROCEEDINGS 46 ( 6) 2042 -2042
1987
HYALURONIDASE PREVENTS EDEMA AND REDUCES CORONARY VASCULAR-RESISTANCE BUT NOT PERMEABILITY INCREASES DURING REPERFUSION FOLLOWING NO-FLOW ISCHEMIA
RG TILTON , PA COLE , SM KRAFT , KB LARSON
INTERNATIONAL JOURNAL OF MICROCIRCULATION-CLINICAL AND EXPERIMENTAL 3 ( 3-4) 441 -441
1984
Real-time imaging and quantification of p300/CBP acetyltransferase inhibition using a FRET-based reporter in living mammalian cells
Jef D. Boeke , Beverley Marie Dancy , Philip A. Cole , Minoru Yoshida
The FASEB Journal 25
2011
Identification and characterization of a novel p300 HAT inhibitor
Andrew Orry , Cecilia Larocca , David J. Meyers , Chandrani Mukherjee
The FASEB Journal 23
2009
Structure and chemistry of the human p300/CBP and yeast Rtt109 histone acetyltransferase
Yong Tang , Xin Liu , Ling Wang , Marc A Holbert
The FASEB Journal 23
2009
Drosophila CBP cooperates with GAGA factor to induce high levels of Pol II promoter-proximal pausing
Mattias Mannervik , Per-Henrik Holmqvist , Ann Boija , David J. Meyers
2014
Down-Regulation of p300/CBP Histone Acetyltransferase Activates a Senescence Checkpoint in Human Melanocytes
Elise Bales , Debdutta Bandyopadhyay , Estela E. Medrano , Philip A. Cole
Cancer Research 62 ( 21) 6231 -6239
200
2002
Retinoids and Carnosol Suppress Cyclooxygenase-2 Transcription by CREB-binding Protein/p300-dependent and -independent Mechanisms
Kotha Subbaramaiah , Philip A. Cole , Andrew J. Dannenberg
Cancer Research 62 ( 9) 2522 -2530
126
2002