Hugo Gutierrez-de-Teran
机构: Associate Professor, Department of Cell and molecular biology, Uppsala University
主页: gpcr-modsim.org
每年引用次数
引用次数
引用: 3,568
H-指数: 35
I10-指数 : 75
出版物: 124
X‐Ray Crystallography and Free Energy Calculations Reveal the Binding Mechanism of A2A Adenosine Receptor Antagonists.
Willem Jespers , Grégory Verdon , Jhonny Azuaje , Maria Majellaro
Angewandte Chemie 59 ( 38) 16536 -16543
6
2020
Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors.
Karin Engen , Sudarsana Reddy Vanga , Thomas Lundbäck , Faith Agalo
ChemistryOpen 9 ( 3) 325 -337
2
2020
Molecular Modelling of G Protein-Coupled Receptors Through the Web.
David Rodríguez , Xabier Bello , Hugo Gutiérrez‐de‐Terán ,
Molecular Informatics 31 ( 5) 334 -341
34
2012
Computational inhibitor design against malaria plasmepsins
S. Bjelic , M. Nervall , H. Gutiérrez-de-Terán , K. Ersmark
Cellular and Molecular Life Sciences 64 ( 17) 2285 -2305
43
2007
Pyrimidine Derivatives as Potent and Selective A3 Adenosine Receptor Antagonists
Vicente Yaziji , David Rodríguez , Hugo Gutiérrez-de-Terán , Alberto Coelho
Journal of Medicinal Chemistry 54 ( 2) 457 -471
44
2011
Recombinant plasmepsin 1 from the human malaria parasite Plasmodium falciparum: Enzymatic characterization, active site inhibitor design, and structural analysis
Peng Liu , Melissa R. Marzahn , Arthur H. Robbins , Hugo Gutiérrez-de-Terán
Biochemistry 48 ( 19) 4086 -4099
19
2009
Molecular dynamics simulations reveal insights into key structural elements of adenosine receptors.
David Rodríguez , Ángel Piñeiro , Hugo Gutiérrez-de-Terán
Biochemistry 50 ( 19) 4194 -4208
57
2011
Free energy calculations of RNA interactions
Christoffer Lind , Mauricio Esguerra , Willem Jespers , Priyadarshi Satpati
Methods 162-163 85 -95
3
2019
New selective A2A agonists and A3 antagonists for human adenosine receptors: synthesis, biological activity and molecular docking studies
Anna Rodriguez , Angel Guerrero , Hugo Gutierrez-de-Teran , David Rodriguez
MedChemComm 6 ( 6) 1178 -1185
7
2015
CONCISE ARTICLE
Anna Rodríguez , Angel Guerrero , Hugo Gutierrez-de-Terán , David Rodríguez
A Series of Analogues to the AT2R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode
Rebecka Isaksson , Jens Lindman , Johan Wannberg , Jessica Sallander
ChemistryOpen 8 ( 1) 114 -125
4
2019
Towards a MIP-based alignment and docking in computer-aided drug design.
Montserrat Barbany , Hugo Gutiérrez-de- Terán , Ferran Sanz , Jordi Villà-Freixa
Proteins 56 ( 3) 585 -594
6
2004
3-Oxopyridazin-5-yl-Chalcone Hybrids : Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation
Abdelaziz El Maatougui , Matilde Yáñez , Abel Crespo , Nuria Fraiz
CHEMISTRYSELECT 2 ( 17) 4920 -4933
1
2017
Visualizing the impact of disease-associated mutations on G protein–nucleotide interactions
Kara Anazia , Lucien Koenekoop , Guillaume Ferré , Enzo Petracco
bioRxiv 2024.01. 30.578006 -2024.01. 30.578006
2024
Structural insights into hA2B affinity and selectivity of 9-deazaxanthines from combined ligand-and structure-based approaches
Angela Stefanachi , Angelo Carotti , Jm Brea , Mi Cadavid
PURINERGIC SIGNALLING 2 S14 -S15
2006
Structural insights into hA2B affinity and selectivity of 9-deazaxanthines (9dAX) from combined ligand-and structure-based approaches
Angela Stefanachi , A Carotti , JM Brea , MI Cadavid
2006
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies
A Carotti , MI Cadavid , NB Centeno , C Esteve
XVIII International Symposium on Medicinal Chemistry
2004
Free Energy Calculations for Protein-Ligand Binding Prediction.
Johan Åqvist , Hugo Gutiérrez-de-Terán , Willem Jespers
Methods of Molecular Biology 2266 203 -226
14
2020
Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Benzopyran-Based Inhibitors.
Johan Åqvist , Hugo Gutiérrez-de-Terán , Hugo Gutiérrez-de-Terán , Anders Hallberg
Frontiers in Molecular Biosciences 8 625274 -625274
2021
Predicting conformational selectivity in a prototypical GPCR
Laura Heitman , Gerard van Westen , Hugo Gutiérrez-de-Terán , Adriaan IJzerman
2020
Johan Åqvist Eddy Sotelo, ORCID: 0000-0001-5571-2812 Willem Jespers Xerardo García Mera, ORCID 0000-0001-5218-6351 Jhonny Alberto Azuaje Guerrero David Rodriguez Diaz Maria Majellaro Laura Heitman Mats Larhed Raymond Stevens Prof. Gerard JP van Westen Rubén Prieto-Díaz Olga Caamaño Santos Vsevolod Katritch Carlos Carbajales orcid: 0000-0002-5177-3981 Sudarsana Reddy Vanga Ana Oliveira Manuel Pastor (ORCID: 0000-0001-8850-1341) Dan Larhammar