引用次数
引用: 79,323
H-指数: 129
I10-指数 : 267
出版物: 488
The activation of phosphatidylinositol 3-kinase by Ras
Tsutomu Kodaki , Rüdiger Woscholski , Bengt Hallberg , Pablo Rodriguez-Viciana Julian Downward
Current Biology 4 ( 9) 798 -806
298
1994
A novel complex comprising BRaf, PKCϵ and S6K2 mediates the pro-survival effects of FGF-2 in small cell lung cancer cells
Richard Marias , Neil Sebire , Ivan Gout , Michael Seckl
Cancer Research 67 2522 -2522
2007
Identification of Novel Gene Expression Targets for the Ras Association Domain Family 1 (RASSF1A) Tumor Suppressor Gene in Non-Small Cell Lung Cancer and Neuroblastoma
Barbara Nicke , John D. Minna , Julian Downward , Reinhard Dammann
Cancer Research 63 ( 17) 5344 -5351
83
2003
The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner
Julian Downward , Nicholas R. Lemoine , Luis M. Martins , Jian Zhao
Journal of Cell Science 113 ( 23) 4363 -4371
242
2000
Ras induces NBT-II epithelial cell scattering through the coordinate activities of Rac and MAPK pathways.
Natacha Edme , Julian Downward , Jean-Paul Thiery , Brigitte Boyer
Journal of Cell Science 115 ( 12) 2591 -2601
77
2002
Abstract #LB-277: An siRNA screen identifies RSK family members as key regulator of lung cancer metastasis
Michael Seckl , Daniel Zicha , Julian Downward , Romain Lara
Cancer Research 69
2009
Chromosomal instability determines taxane sensitivity - supplementary materials
Maik Kschischo , Barbara Nicke , Thomas Ried , Julian Downward
2009
Abstract B26: The SHOC2 phosphatase complex as a therapeutic target for ERK-pathway inhibition in RAS-driven tumors
Pablo Rodriguez-Viciana , Miriam Molina-Arcas , Julian Downward , Mona A. El-Bahrawy
Molecular Cancer Research 18
2020
Abstract B11: RAS orchestrates the increase of interstitial adenosine in lung adenocarcinoma to promote immune evasion
Julian Downward , Chris Moore , Sophie de Carné , Philip East
Cancer immunology research 8
2020
Abstract B19: New tools to study the role of RAS/CRAF interaction in RAS-driven lung cancer
Miriam Molina-Arcas , Julian Downward , Ian Rosewell , David Hancock
Molecular Cancer Research 18
2020
Abstract IA06: Oncogenic Ras control of the tumor immune microenvironment
Julian Downward
Molecular Cancer Research 18
2020
Characterisation of tumour immune microenvironment remodelling following oncogene inhibition in preclinical studies using an optimised imaging mass cytometry workflow
Febe van Maldegem , Miriam Molina-Arcas , Julian Downward , Julian Downward
bioRxiv
1
2021
Quantitative Proteomic Analysis in Alveolar Type II Cells Reveals the Different Capacities of RAS and TGF-β to Induce Epithelial–Mesenchymal Transition
Julian Downward , Mark G. Jones , Paul Skipp , Donna E. Davies
Frontiers in Molecular Biosciences 8 595712 -595712
2021
Correction: WDHD1 is essential for the survival of PTEN-inactive triple-negative breast cancer.
Marcin R Przewloka , Julian Downward , Paul Skipp , Rob M Ewing
Cell Death and Disease 12 ( 3) 269 -269
2021
Clinical impact of subclonal EGFR T790M mutations in advanced-stage EGFR-mutant non-small-cell lung cancers
Julian Downward , Aleksandra Markovets , Elza C de Bruin , Kenneth S Thress
Nature Communications 12 ( 1) 1780 -1780
2021
Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies
Michael Steckel , Miriam Molina-Arcas , Britta Weigelt , Michaela Marani
Cell Research 22 ( 8) 1227 -1245
196
2012
Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer
Rebecca Roylance , David Endesfelder , Patricia Gorman , Rebecca A Burrell
Cancer Epidemiology, Biomarkers & Prevention 20 ( 10) 2183 -2194
107
2011
Interleukin (IL)-2 activation of p21ras in murine myeloid cells transfected with human IL-2 receptor β chain
Warren J. Leonard , Doreen A. Cantrell , Manuel Izquierdo , Julian Downward
European Journal of Immunology 22 ( 3) 817 -821
24
1992
How BAD phosphorylation is good for survival.
Julian Downward
Nature Cell Biology 1 ( 2)
210
1999
Matrix detachment induces caspase-dependent cytochrome c release from mitochondria: inhibition by PKB/Akt but not Raf signalling.
Marjatta Rytömaa , Kerstin Lehmann , Julian Downward
Oncogene 19 ( 39) 4461 -4468
124
2000