Methods and compositions in checkpoint signaling

Stephen J Elledge , David K Cortez , Lee Zou

13
2006
1999
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

Stephen J. Elledge , Parvin Yazdi , Jun Qin , David Cortez
Genes & Development 14 ( 8) 927 -939

1,583
2000
Chk1 is an essential kinase that is regulated by Atr and required for the G2/M DNA damage checkpoint

Stephen J. Elledge , Sandra Carattini-Rivera , Shuhei Matsuoka , Allan Bradley
Genes & Development 14 ( 12) 1448 -1459

2,064
2000
RADX controls RAD51 filament dynamics to regulate replication fork stability.

Walter J. Chazin , Mauro Modesti , Eric C. Greene , Madison B. Adolph
Molecular Cell 81 ( 5)

1
2021
ATR activation is regulated by dimerization of ATR activating proteins.

David Cortez , Vaughn Thada
Journal of Biological Chemistry 296 100455 -100455

2021
A Synthetic Lethal Screen Identifies DNA Repair Pathways that Sensitize Cancer Cells to Combined ATR Inhibition and Cisplatin Treatments

Kareem N. Mohni , Petria S. Thompson , Jessica W. Luzwick , Gloria G. Glick
PLOS ONE 10 ( 5) e0125482

73
2015
Characterization of stable high molecular weight mutagenic product(s) of plant-activated m-phenylenediamine

Kwang-Young Seo , Joan Riley , David Cortez , Elizabeth D. Wagner
Mutation Research\/genetic Toxicology 299 ( 2) 111 -120

25
1993
Sensitivity to Poly(ADP-ribose) Polymerase (PARP) Inhibition Identifies Ubiquitin-specific Peptidase 11 (USP11) as a Regulator of DNA Double-strand Break Repair

Timothy D. Wiltshire , Courtney A. Lovejoy , Tong Wang , Fen Xia
Journal of Biological Chemistry 285 ( 19) 14565 -14571

106
2010
116
2015
Common mechanisms of PIKK regulation

Courtney A. Lovejoy , David Cortez
DNA Repair 8 ( 9) 1004 -1008

339
2009
A role for CDK9-cyclin K in maintaining genome integrity.

David S. Yu , David Cortez
Cell Cycle 10 ( 1) 28 -32

33
2011
Maintenance of Genome Stability and Breast Cancer: Molecular Analysis of DNA Damage-Activated Kinases

Heather L. Ball , Mark Ehrhardt , Daniel Mordes , David Cortez
Defense Technical Information Center

2007
RPA and RAD51: fork reversal, fork protection, and genome stability

Kamakoti P. Bhat , David Cortez
Nature Structural & Molecular Biology 25 ( 6) 446 -453

241
2018
An intrinsic S/G2 checkpoint enforced by ATR

Joshua C Saldivar , Stephan Hamperl , Michael J Bocek , Mingyu Chung
Science 361 ( 6404) 806 -810

108
2018
Common motifs in ETAA1 and TOPBP1 required for ATR kinase activation

Vaughn Thada , David Cortez
Journal of Biological Chemistry 294 ( 21) 8395 -8402

15
2019
A novel splice site mutation in SMARCAL1 results in aberrant exon definition in a child with Schimke immunoosseous dysplasia.

Clinton Carroll , Tracy E. Hunley , Yan Guo , David Cortez
American Journal of Medical Genetics Part A 167 ( 10) 2260 -2264

10
2015
ATRIP oligomerization is required for ATR-dependent checkpoint signaling

Heather L. Ball , David Cortez
Journal of Biological Chemistry 280 ( 36) 31390 -31396

69
2005