Oscar Vadas
机构: Postdoc at the Medical Research Council - Laboratory of Molecular Biology, Cambridge, UK
每年引用次数
引用次数
引用: 2,619
H-指数: 20
I10-指数 : 27
出版物: 53
Deciphering the dynamic regulation of phosphoinositide 3-kinases downstream of G-protein coupled receptors and receptor tyrosine kinases (1008.1)
Olga Perisic , John Burke , Oscar Vadas , Roger L Williams
The FASEB Journal 28
2014
Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Dominique Soldati-Favre , Christopher L. King , Christopher L. King , Wai-Hong Tham
Nature Communications 12 ( 1) 1538 -1538
2021
Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA)
John E. Burke , Olga Perisic , Glenn R. Masson , Oscar Vadas
Proceedings of the National Academy of Sciences of the United States of America 109 ( 38) 15259 -15264
162
2012
Multimeric peptides as agonists of the erythropoietin receptor
Oscar Vadas , Keith Rose
Advances in Experimental Medicine and Biology 611 505 -506
2
2009
Probing the dynamic regulation of peripheral membrane proteins using hydrogen deuterium exchange–MS (HDX–MS)
Oscar Vadas , John E. Burke
Biochemical Society Transactions 43 ( 5) 773 -786
37
2015
Auxiliary domains of the HrpB bacterial DExH-box helicase shape its RNA preferences.
Stéphane Hausmann , Johan Geiser , Oscar Vadas , Verena Ducret
RNA Biology 17 ( 5) 637 -650
2
2020
A Coincidence Detection Mechanism Controls PX-BAR Domain-Mediated Endocytic Membrane Remodeling via an Allosteric Structural Switch
Wen-Ting Lo , Andreja Vujičić Žagar , Fabian Gerth , Martin Lehmann
Developmental Cell 43 ( 4) 522 -529
19
2017
Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain Module.
Haibin Wang , Wen-Ting Lo , Andreja Vujičić Žagar , Federico Gulluni
Molecular Cell 71 ( 2) 343
20
2018
Multivalency—a way to enhance binding avidities and bioactivity—preliminary applications to EPO
Oscar Vadas , Keith Rose
Journal of Peptide Science 13 ( 9) 581 -587
11
2007
Dynamics of the Phosphoinositide 3-Kinase p110δ Interaction with p85α and Membranes Reveals Aspects of Regulation Distinct from p110α
John E. Burke , Oscar Vadas , Alex Berndt , Tara Finegan
Structure 19 ( 8) 1127 -1137
64
2011
SUV39 SET domains mediate crosstalk of heterochromatic histone marks
Alessandro Stirpe , Nora Guidotti , Sarah Northall , Sinan Kilic
bioRxiv
11
2020
Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism
Xuxiao Zhang , Oscar Vadas , Olga Perisic , Karen E. Anderson
Molecular Cell 41 ( 5) 567 -578
130
2011
Abstract IA02: G-proteins regulating PI3Ks and PI4KIIIβ regulating a G-protein
John E. Burke , Alison J. Inglis , Oscar Vadas , Olga Perisic
Molecular Cancer Therapeutics 14
2015
Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma.
Lluc Farrera-Soler , Jean-Pierre Daguer , Sofia Barluenga , Oscar Vadas
PLOS ONE 15 ( 9)
26
2020
Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity.
Aliaksei Shymanets , Prajwal , Oscar Vadas , Cornelia Czupalla
Biochemical Journal 469 ( 1) 59 -69
9
2015
Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1
Gillian L. Dornan , Braden D. Siempelkamp , Meredith L. Jenkins , Oscar Vadas
Proceedings of the National Academy of Sciences of the United States of America 114 ( 8) 1982 -1987
60
2017
PI3Kβ downstream of GPCRs - crucial partners in oncogenesis.
Hashem A Dbouk , Oscar Vadas , Roger L Williams , Jonathan M Backer
Oncotarget 3 ( 12) 1485 -1486
4
2012
Structural Basis for Activation and Inhibition of Class I Phosphoinositide 3-Kinases
Oscar Vadas , John E. Burke , Xuxiao Zhang , Alex Berndt
Science Signaling 4 ( 195) 2002165
202
2011
Gβγ is a direct regulator of endogenous p101/p110γ and p84/p110γ PI3Kγ complexes in mouse neutrophils
Natalie K. Rynkiewicz , Karen E. Anderson , Sabine Suire , Daniel M. Collins
Science Signaling 13 ( 656)
1
2020
PICarver: a software tool and strategy for peptides isoelectric focusing.
Ali R. Vaezzadeh , Céline Hernandez , Oscar Vadas , Jacques J. M. Deshusses
Journal of Proteome Research 7 ( 10) 4336 -4345
8
2008