Formation of the insulin-containing secretory granule core occurs within immature beta-granules.
Xue Fen Huang , P. Arvan
Journal of Biological Chemistry 269 ( 33) 20838 -20844
68
1994
Polarized targeting of epithelial cell proteins in thyrocytes and MDCK cells.
J.W. Harney , R.S. Ahima , D. Prabakaran , P.R. Larsen
Journal of Cell Science 112 ( 8) 1247 -1256
20
1999
Protein Production and Secretion in Exocrine Cells
J. D. Castle , P. Arvan , R. Cameron
Journal of Dental Research 66 ( 1_suppl) 633 -637
15
1987
Constitutive protein secretion from the exocrine pancreas of fetal rats.
P. Arvan , A. Chang
Journal of Biological Chemistry 262 ( 8) 3886 -3890
23
1987
New Insights into Thyroglobulin Pathophysiology Revealed by the Study of a Family with Congenital Goiter
D. Peteiro-Gonzalez , J. Lee , J. Rodriguez-Fontan , I. Castro-Piedras
The Journal of Clinical Endocrinology and Metabolism 95 ( 7) 3522 -3526
20
2010
Protein discharge from immature secretory granules displays both regulated and constitutive characteristics.
P. Arvan , R. Kuliawat , D. Prabakaran , A.M. Zavacki
Journal of Biological Chemistry 266 ( 22) 14171 -14174
122
1991
Folding and assembly of newly synthesized thyroglobulin occurs in a pre-Golgi compartment.
P.S. Kim , P. Arvan
Journal of Biological Chemistry 266 ( 19) 12412 -12418
73
1991
Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants
T. J. Nicolson , E. A. Bellomo , N. Wijesekara , M. K. Loder
Diabetes 58 ( 9) 2070 -2083
408
2009
In Vivo Misfolding of Proinsulin Below the Threshold of Frank Diabetes
I. Hodish , A. Absood , L. Liu , M. Liu
Diabetes 60 ( 8) 2092 -2101
30
2011
Impaired Cleavage of Preproinsulin Signal Peptide Linked to Autosomal-Dominant Diabetes
M. Liu , R. Lara-Lemus , S.-o. Shan , J. Wright
Diabetes 61 ( 4) 828 -837
37
2012
Inhibitors of membrane transport reduce lysosomal enzyme secretion from dogfish phagocytes and their killing of sea urchin eggs
P. Dunham , P. Arvan , S. Falkow , S. Hoffstein
Proceedings of the National Academy of Sciences of the United States of America 76 ( 4) 1873 -1877
2
1979
Disulfide-linked aggregation of thyroglobulin normally occurs during nascent protein folding
P. S. Kim , K. R. Kim , P. Arvan
American Journal of Physiology-cell Physiology 265 ( 3)
37
1993
Proinsulin maturation, misfolding, and proteotoxicity
M. Liu , I. Hodish , C. J. Rhodes , P. Arvan
Proceedings of the National Academy of Sciences of the United States of America 104 ( 40) 15841 -15846
126
2007
Intracellular iodination of thyroglobulin in filter-polarized thyrocytes leads to the synthesis and basolateral secretion of thyroid hormone.
R. Kuliawat , P. Arvan
Journal of Biological Chemistry 269 ( 7) 4922 -4927
13
1994
Polarized secretion of thrombospondin is opposite to thyroglobulin in thyroid epithelial cells
D. Prabakaran , P. Kim , K.R. Kim , P. Arvan
Journal of Biological Chemistry 268 ( 12) 9041 -9048
24
1993
Hormonal regulation of thyroglobulin export from the endoplasmic reticulum of cultured thyrocytes.
P.S. Kim , P. Arvan
Journal of Biological Chemistry 268 ( 7) 4873 -4879
47
1993
A novel transgenic mouse model of growth plate dysplasia reveals that decreased chondrocyte proliferation due to chronic ER stress is a key factor in reduced bone growth.
B. Gualeni , M. H. Rajpar , A. Kellogg , P. A. Bell
Disease Models & Mechanisms 6 ( 6) 1414 -1425
19
2013
Islet Autoantigens: Structure, Function, Localization, and Regulation
P. Arvan , M. Pietropaolo , D. Ostrov , C. J. Rhodes
Cold Spring Harbor Perspectives in Medicine 2 ( 8)
65
2012
A SINGLE AMINO ACID CHANGE IN THE ACETYLCHOLINESTERASE-LIKE DOMAIN OF THYROGLOBULIN CAUSES CONGENITAL GOITER WITH HYPOTHYROIDISM IN THE COG/COG MOUSE : A MODEL OF HUMAN ENDOPLASMIC RETICULUM STORAGE DISEASES
P. S. Kim , S. A. Hossain , Y.-N. Park , I. Lee
Proceedings of the National Academy of Sciences of the United States of America 95 ( 17) 9909 -9913
105
1998
Folding of thyroglobulin in the calnexin/calreticulin pathway and its alteration by loss of Ca2+ from the endoplasmic reticulum.
Bruno DI JESO , Luca ULIANICH , Francesco PACIFICO , Antonio LEONARDI
Biochemical Journal 370 ( 2) 449 -458
45
2003