Loren D. Walensky
机构: Professor of Pediatrics, Dana-Farber Cancer Institute and Harvard Medical School
主页: walenskylab.org
每年引用次数
引用次数
引用: 19,610
H-指数: 65
I10-指数 : 122
出版物: 283
Inositol 1,4,5-trisphosphate receptors selectively localized to the acrosomes of mammalian sperm.
L D Walensky , S H Snyder
Journal of Cell Biology 130 ( 4) 857 -869
242
1995
Brain and testicular tumors in mice with progenitor cells lacking BAX and BAK
S G Katz , J K Fisher , M Correll , R T Bronson
Oncogene 32 ( 35) 4078 -4085
6
2013
Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting
F Wachter , A M Morgan , M Godes , R Mourtada
Oncogene 36 ( 15) 2184 -2190
22
2017
Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia
C Reynolds , J E Roderick , J L LaBelle , G Bird
Leukemia 28 ( 9) 1819 -1827
42
2014
BCL-2 in the crosshairs: tipping the balance of life and death.
L D Walensky
Cell Death & Differentiation 13 ( 8) 1339 -1350
198
2006
Evaluation and critical assessment of putative MCL-1 inhibitors.
S Varadarajan , M Vogler , M Butterworth , D Dinsdale
Cell Death & Differentiation 20 ( 11) 1475 -1484
81
2013
Stemming danger with Golgified BAX.
Loren D. Walensky
Molecular Cell 46 ( 5) 554 -556
2
2012
Inhibition of Pro-Apoptotic BAX by a Noncanonical Interaction Mechanism
Lauren A. Barclay , Thomas E. Wales , Thomas P. Garner , Franziska Wachter
Molecular Cell 57 ( 5) 873 -886
137
2015
Phospho-BAD BH3 Mimicry Protects β Cells and Restores Functional β Cell Mass in Diabetes
Sanda Ljubicic , Klaudia Polak , Accalia Fu , Jessica Wiwczar
Cell Reports 10 ( 4) 497 -504
22
2015
A Competitive Stapled Peptide Screen Identifies a Selective Small Molecule that Overcomes MCL-1-Dependent Leukemia Cell Survival
Nicole A. Cohen , Michelle L. Stewart , Evripidis Gavathiotis , Jared L. Tepper
Chemistry & Biology 19 ( 9) 1175 -1186
117
2012
Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3.
Amanda L. Edwards , Evripidis Gavathiotis , James L. LaBelle , Craig R. Braun
Chemistry & Biology 20 ( 7) 888 -902
52
2013
Selective Covalent Targeting of Anti-Apoptotic BFL-1 by Cysteine-Reactive Stapled Peptide Inhibitors
Annissa J. Huhn , Rachel M. Guerra , Edward P. Harvey , Gregory H. Bird
Chemistry & Biology 23 ( 9) 1123 -1134
39
2016
464 Regulation of apoptosis by synthetic helices of the BCL-2 family
L. Walensky , A. Kung , I. Escher , T. Malia
Ejc Supplements 2 ( 8) 141
1
2004
20 Direct Targeting of Pro-apoptotic BAX for Cancer Therapy
D. Reyna , J. Bellairs , L. Walensky , E. Gavathiotis
European Journal of Cancer 48 10
2
2012
Péptidos alfa helicoidales adecuados para activar o inhibir la muerte celular
Loren D Walenski , Gregory Verdine , Stanley J Korsmeyer
2016
Alpha-helix peptides suitable for activating or inhibiting cell death
Loren D Walenski , Gregory Verdine , Stanley J Korsmeyer
2016
Alpha-helical peptides suitable for activating or inhibiting cell death
Loren D Walenski , Gregory Verdine , Stanley J Korsmeyer
2016
A family of distinct protein 4.1 genes is expressed in human tissues
M Parra , P Gascard , L Walensky , S Snyder
MOLECULAR BIOLOGY OF THE CELL 8 1023 -1023
6
1997
Cloning of a novel human gene with high homology to the erythroid membrane skeletal protein 4.1
M Parra , P Gascard , L Walensky , S Snyder
MOLECULAR BIOLOGY OF THE CELL 7 3213 -3213
2
1996
Dissecting the BCL‐2 family interaction network with stapled peptides: mechanistic insights and pharmacologic opportunities
Loren David Walensky
The FASEB Journal 26 220.1 -220.1
2012