引用次数
引用: 37,485
H-指数: 91
I10-指数 : 183
出版物: 298
Exposure of Pancreatic β-Cells to Excess Glucose Results in Bimodal Activation of mTORC1 and mTOR-Dependent Metabolic Acceleration
Courtney Zasha Rumala , Juan Liu , Jason Wei Locasale , Barbara Ellen Corkey
iScience 23 ( 2) 100858
2020
mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation
Hu Zeng , Sivan Cohen , Cliff Guy , Sharad Shrestha
Immunity 45 ( 3) 540 -554
172
2016
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
Haoqiang Ying , Alec C. Kimmelman , Costas A. Lyssiotis , Sujun Hua
Cell 149 ( 3) 656 -670
1,723
2012
Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival.
Caroline H. Yi , Heling Pan , Jan Seebacher , Il-Ho Jang
Cell 146 ( 4) 607 -620
162
2011
Metabolic Flux and the Regulation of Mammalian Cell Growth
Jason W. Locasale , Lewis C. Cantley
Cell Metabolism 14 ( 4) 443 -451
268
2011
Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism
Samantha J. Mentch , Mahya Mehrmohamadi , Lei Huang , Xiaojing Liu
Cell Metabolism 22 ( 5) 861 -873
462
2015
AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival.
Rigel J. Kishton , Carson E. Barnes , Amanda G. Nichols , Sivan Cohen
Cell Metabolism 23 ( 4) 649 -662
105
2016
Metformin Targets Central Carbon Metabolism and Reveals Mitochondrial Requirements in Human Cancers
Xiaojing Liu , Iris L. Romero , Lacey M. Litchfield , Ernst Lengyel
Cell Metabolism 24 ( 5) 728 -739
130
2016
mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.
Daming Gao , Hiroyuki Inuzuka , Meng-Kwang Marcus Tan , Hidefumi Fukushima
Molecular Cell 44 ( 2) 290 -303
190
2011
The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Kazutaka Sumita , Yu-Hua Lo , Koh Takeuchi , Miki Senda
Molecular Cell 61 ( 2) 187 -198
32
2016
ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer.
Sunghee Park , Ching-Yi Chang , Rachid Safi , Xiaojing Liu
Cell Reports 15 ( 2) 323 -335
63
2016
Targeting One Carbon Metabolism with an Antimetabolite Disrupts Pyrimidine Homeostasis and Induces Nucleotide Overflow
Zheng Ser , Xia Gao , Christelle Johnson , Mahya Mehrmohamadi
Cell Reports 15 ( 11) 2367 -2376
38
2016
Characterization of the usage of the serine metabolic network in human cancer
Mahya Mehrmohamadi , Xiaojing Liu , Alexander A. Shestov , Jason W. Locasale
Cell Reports 9 ( 4) 1507 -1519
135
2014
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
Ping-Chih Ho , Jessica Dauz Bihuniak , Andrew N. Macintyre , Matthew Staron
Cell 162 ( 6) 1217 -1228
1,035
2015
A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect
Ziwei Dai , Alexander A. Shestov , Luhua Lai , Jason W. Locasale
Biophysical Journal 111 ( 5) 1088 -1100
30
2016
A Mass Spectrometry Platform to Quantitatively Profile Cancer Cell Metabolism from Cell Lines to Tissues.
J. Asara , N. Perrimon , J. Locasale , L. Cantley
Journal of biomolecular techniques 21
2010
Transcriptional regulation of prostate cancer metabolism
R.R. Gomis , J. Locasale , A. Carracedo , L. Valcarcel
European Journal of Cancer 61
2016
Sel1L is Indispensable for Mammalian ERAD, ER Homeostasis and Survival
Jason W. Locasale , Qiaoming Long , Shengyi Sun , John R. Yates Iii
Wageningen University
2013
Evolved resistance to GAPDH inhibition results in loss of the Warburg Effect but retains a different state of glycolysis
Jason W. Locasale , Kris C. Wood , Jun O. Liu , Maria V. Liberti
bioRxiv 602557
2019
The Na+/K+ ATPase Regulates Glycolysis and Defines Immunometabolism in Tumors
Jason W. Locasale , David G. Kirsch , Simon G. Gregory , Maria V. Liberti
bioRxiv
1
2020
Lewis Cantley Ziwei Dai Maria Liberti Sydney Sanderson Marc O. Warmoes Mahya Mehrmohamadi Andrew Macintyre Alexander A. Shestov Ahmad A. Cluntun Sailendra Nichenametla Atsuo T. Sasaki Valerie Gerriets Evan Dale Abel Gerhard Wagner Katherine R Mattaini Tamer T. Onder J.Wade Harper Gregory Stephanopoulos William Israelsen