IL-18 promotes wound healing and has anti-angiogenic properties in the eye

Peter Humphries , Sarah Doyle , Sarah Doyle , Francisco J Lopez
Investigative Ophthalmology & Visual Science 56 ( 7) 2462 -2462

2015
AAV Mediated Systemic Low Molecular Weight Drug Delivery To The Retina

Peter Humphries , Paul F. Kenna , Anna-Sophia Kiang , Anh T. Nguyen
Investigative Ophthalmology & Visual Science 53 ( 14) 4162 -4162

2012
Claudin5 Mediates Lrp5-regulated Retinal Blood Vessel Growth

Lois E. Smith , Molly R. Seaward , Aimee M. Juan , Colman J. Hatton
Investigative Ophthalmology & Visual Science 52 ( 14) 4358 -4358

2011
2013
NLRP3 independent mechanisms of RPE cell death

Peter Humphries , Sarah L Doyle , Ema Ozaki , Peter S Adamson
Investigative Ophthalmology & Visual Science 55 ( 13) 1318 -1318

2014
Deletion of interleukin-33 (IL33) results in persistent Müller cell activation during retinal detachment

Alan W Stitt , Sarah Doyle , Heping Xu , Sofia Pavlou
Investigative Ophthalmology & Visual Science 57 ( 12) 5383 -5383

2016
Investigating a role for Toll like receptor signaling in the pathogenesis of Age Related Macular Degeneration (AMD).

Kelly Mulfaul , Kiva Brennan , Kiva Brennan , Sarah Doyle
Investigative Ophthalmology & Visual Science 57 ( 12) 5010 -5010

2016
Interleukin-33 deficiency resulted in severe neuroretinal degeneration in retinal detachment

Mei Chen , Josy Augustine , Sofia Pavlou , Imran Ali
Investigative Ophthalmology & Visual Science 59 ( 9) 3942 -3942

2018
INDUCIBLE MMP-3 EXPRESSION IN A STEROID-INDUCED MURINE MODEL OF GLAUCOMA

Jeffrey O'Callaghan , Paul S Cassidy , Ester Reina-Torres , Joseph Sherwood
Investigative Ophthalmology & Visual Science 59 ( 9) 3505 -3505

2018
TLR2 bridges oxidative damage and complement-associated pathology and is a therapeutic target for age-related macular degeneration.

Kathleen Chirco , Kelly Mulfaul , Arvydas Maminishkis , Robert F Mullins
Investigative Ophthalmology & Visual Science 59 ( 9) 3475 -3475

2018
Variability in therapeutic outcome due to age of P23H rhodopsin mice at time of dosing can be reduced by enhanced retinal drug delivery.

Peter Humphries , Paul Kenna , James Keaney , Jane G Farrar
Investigative Ophthalmology & Visual Science 59 ( 9) 1013 -1013

2018
Aberrant BMAL1 dependent claudin-5 cycling induces geographic atrophy

Lucia Celkova , Sarah Doyle , Sarah Doyle , Natalie Hudson
Investigative Ophthalmology & Visual Science 59 ( 9) 3469 -3469

1
2018
Fundus fluorescein angiography (FFA) in human subjects displays circadian variation

Sarah Doyle , Alan Hopkins , Alan Hopkins , Natalie Hudson
Investigative Ophthalmology & Visual Science 60 ( 9) 5268 -5268

2019
AAV-BASED GENE THERAPY FOR GLAUCOMA

Peter Humphries , Jeffrey O'callaghan , Matthew Campbell

2019
The presence of ADAMs in the eye: Exploring a promising therapeutic target for age-related macular degeneration

Joanne A Matsubara , Mackenzie Ann Campbell , Matthew Campbell , Jing Z Cui
Investigative Ophthalmology & Visual Science 60 ( 9) 1239 -1239

2019
Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy.

Amaya Sanz-Rodriguez , Niamh M.C. Connolly , Vamshidhar R. Vangoor , Brenton L. Cavanagh
Molecular Therapy 29 ( 6) 2041 -2052

1
2021
Interleukin-33 regulates metabolic reprogramming of the retinal pigment epithelium in response to immune stressors

Andrew P. Halestrap , Ed C. Lavelle , Nicholas Jones , Andrew D. Dick
JCI insight 6 ( 8) 129429

2021
Vascular expression of permeability-resistant occludin mutant preserves visual function in diabetes.

Alyssa Dreffs , Jason Keil , David A. Antonetti , Sarah Sheskey
Diabetes

2021
Advanced late-onset retinitis pigmentosa with dominant-acting D477G RPE65 mutation is responsive to oral synthetic retinoid therapy

Paul F Kenna , Marian M Humphries , Anna-Sophia Kiang , Philippe Brabet
BMJ Open Ophthalmology 5 ( 1)

6
2020
Protection of Photoreceptors in a Mouse Model of RP10

Lawrence C.S. Tam , Anna-Sophia Kiang , Naomi Chadderton , Paul F. Kenna
Retinal Degenerative Diseases 664 559 -565

5
2010