引用次数
引用: 3,517
H-指数: 23
I10-指数 : 31
出版物: 51
MECHANISM OF ACTION DERIVATION FOR DRUG CANDIDATE ADVERSE DRUG REACTION PREDICTIONS
Heng Luo , Jianying Hu , Janu Verma , Ping Zhang
2019
Drug Repurposing Hypothesis Generation Using Clinical Drug-Drug Interaction Information
Heng Luo , Ping Zhang
2020
Combining Docking Pose Rank and Structure with Deep Learning Improves Protein–Ligand Binding Mode Prediction over a Baseline Docking Approach
Tien Huynh , Jeffrey K. Weber , Wendy D. Cornell , Joseph A. Morrone
Journal of Chemical Information and Modeling 60 ( 9) 4170 -4179
59
2020
DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical–protein interactome
Heng Luo , Jian Chen , Leming Shi , Mike Mikailov
Nucleic Acids Research 39 492 -498
145
2011
Molecular Docking for Identification of Potential Targets for Drug Repurposing.
Heng Luo , William Mattes , Donna L Mendrick , Huixiao Hong
Current Topics in Medicinal Chemistry 16 ( 30) 3636 -3645
13
2016
Development and Validation of Decision Forest Model for Estrogen Receptor Binding Prediction of Chemicals Using Large Data Sets
Hui Wen Ng , Stephen W. Doughty , Heng Luo , Hao Ye
Chemical Research in Toxicology 28 ( 12) 2343 -2351
25
2015
Estrogenic activity data extraction and in silico prediction show the endocrine disruption potential of bisphenol A replacement compounds.
Hui Wen Ng , Mao Shu , Heng Luo , Hao Ye
Chemical Research in Toxicology 28 ( 9) 1784 -1795
72
2015
SePreSA: a server for the prediction of populations susceptible to serious adverse drug reactions implementing the methodology of a chemical–protein interactome
Lun Yang , Heng Luo , Jian Chen , Qinghe Xing
Nucleic Acids Research 37 406 -412
47
2009
sNebula, a network-based algorithm to predict binding between human leukocyte antigens and peptides.
Heng Luo , Hao Ye , Hui Wen Ng , Sugunadevi Sakkiah
Scientific Reports 6 ( 1) 32115 -32115
14
2016
Machine-Learning Prediction of Oral Drug-Induced Liver Injury (DILI) via Multiple Features and Endpoints.
Xiaobin Liu , Danhua Zheng , Yi Zhong , Zhaofan Xia
BioMed Research International 2020 4795140
2020
Applying network analysis and Nebula (neighbor-edges based and unbiased leverage algorithm) to ToxCast data.
Hao Ye , Heng Luo , Hui Wen Ng , Joe Meehan
Environment International 89 81 -92
4
2016
Comparison of RNA-seq and microarray-based models for clinical endpoint prediction
Wenqian Zhang , Ying Yu , Falk Hertwig , Jean Thierry-Mieg
Genome Biology 16 ( 1) 133 -133
330
2015
Molecular docking to identify associations between drugs and class I human leukocyte antigens for predicting idiosyncratic drug reactions.
Heng Luo , Tingting Du , Peng Zhou , Lun Yang
Combinatorial Chemistry & High Throughput Screening 18 ( 3) 296 -304
65
2015
Molecular Docking for Prediction and Interpretation of Adverse Drug Reactions.
Achille Fokoue-Nkoutche , Nalini Singh , Lun Yang , Jianying Hu
Combinatorial Chemistry & High Throughput Screening 21 ( 5) 314 -322
6
2018
DDI-CPI, a server that predicts drug–drug interactions through implementing the chemical–protein interactome
Heng Luo , Ping Zhang , Hui Huang , Jialiang Huang
Nucleic Acids Research 42 46 -52
73
2014
Exploring Off-Targets and Off-Systems for Adverse Drug Reactions via Chemical-Protein Interactome — Clozapine-Induced Agranulocytosis as a Case Study
Lun Yang , Kejian Wang , Jian Chen , Anil G. Jegga
PLoS Computational Biology 7 ( 3) e1002016
111
2011
FOLDNA, a Web Server for Self-Assembled DNA Nanostructure Autoscaffolds and Autostaples
Chensheng Zhou , Heng Luo , Xiaolu Feng , Xingwang Li
Journal of Nanotechnology 2012 453 -457
4
2012
DrugPathSeeker: Interactive UI for exploring drug-ADR relation via pathways
Janu Verma , Heng Luo , Jianying Hu , Ping Zhang
ieee pacific visualization symposium 260 -264
2
2017
Predicting adverse drug reactions through interpretable deep learning framework
Sanjoy Dey , Heng Luo , Achille Fokoue , Jianying Hu
BMC Bioinformatics 19 ( 21) 1 -13
96
2018
Homology Model and Ligand Binding Interactions of the Extracellular Domain of the Human α4β2 Nicotinic Acetylcholine Receptor
Shu Mao , Hui Wen Ng , Michael Orr , Heng Luo
Journal of Biomedical Science and Engineering 09 ( 1) 41 -100
3
2016