From Adaptive Design to Modern Protocol Design for Drug Development: Part II. Success Probabilities and Effect Estimates for Phase 3 Development Programs
Frank Brefz , Sue-Jane Wang
Drug Information Journal 44 ( 3) 333 -342
9
2010
Multiple Comparisons Using R
Torsten Hothorn , Peter H. Westfall , Frank Bretz
1,445
2010
Recent developments in multiple comparison procedures
Yoav Benjamini , Sanat Sarkar , Frank Bretz
Institute of Mathematical Statistics
9
2004
Computation of Multivariate Normal and t Probabilities
Frank Bretz , Alan Genz
424
2009
Efficient two-sample designs for microarray experiments with biological replications.
Jobst Landgrebe , Edgar Brunner , Frank Bretz
in Silico Biology 4 ( 4) 461 -470
20
2004
On the efficiency of adaptive designs
Björn Bornkamp , Holger Dette , Frank Bretz
1
2010
Interview with Editor of Statistics in Biopharmaceutical Research
Frank Bretz
AMSTAT news: the membership magazine of the American Statistical Association ( 479) 9
2017
Model Selection versus Model Averaging in Dose Finding Studies
Kirsten Schorning , Björn Bornkamp , Holger Dette , Frank Bretz
arXiv: Applications
56
2015
Equivalence tests for binary efficacy-toxicity responses
Holger Dette , Frank Bretz , Kathrin Möllenhoff
arXiv: Methodology
1
2019
A unified framework for weighted parametric multiple test procedures.
Ekkehard Glimm , Ekkehard Glimm , Dong Xi , Frank Bretz
Biometrical Journal 59 ( 5) 918 -931
10
2017
Model‐based dose finding under model uncertainty using general parametric models
Björn Bornkamp , Frank Bretz , José Pinheiro , Ekkehard Glimm
Statistics in Medicine 33 ( 10) 1646 -1661
74
2014
Estimands-What they are and why they are important for pharmacometricians.
Mouna Akacha , Michael Looby , Björn Bornkamp , Heinz Schmidli
CPT: Pharmacometrics & Systems Pharmacology 10 ( 4) 279 -282
1
2021
Statistics in Biopharmaceutical Research Best Papers Award
Toshimitsu Hamasaki , Frank Bretz
Statistics in Biopharmaceutical Research 13 ( 2) 129 -130
2021
Statistical analysis of monotone or non-monotone dose-response data from in vitro toxicological assays.
Frank Bretz , Ludwig A. Hothorn
Atla-alternatives To Laboratory Animals 31 81 -96
47
2003
Dose-response and thresholds in mutagenicity studies: a statistical testing approach.
Ludwig A. Hothorn , Frank Bretz
Atla-alternatives To Laboratory Animals 31 97 -103
3
2003
Methods That Approximate the Problem
Alan Genz , Frank Bretz , Alan Genz , Frank Bretz
Computation of Multivariate Normal and t Probabilities 21 -27
1
2009
Methods That Approximate the Integral
Alan Genz , Frank Bretz , Alan Genz , Frank Bretz
Computation of Multivariate Normal and t Probabilities 29 -54
1
2009
Special Cases
Alan Genz , Frank Bretz , Alan Genz , Frank Bretz
Computation of Multivariate Normal and t Probabilities 7 -20
2009
Further Topics
Alan Genz , Frank Bretz , Alan Genz , Frank Bretz
Computation of Multivariate Normal and t Probabilities 55 -69
2009
Analysis of Dose–Response Studies—Modeling Approaches
José C. Pinheiro , Frank Bretz , Michael Branson
Springer, New York, NY 146 -171
47
2006