NOTCH1 Regulates Osteoclastogenesis Directly in Osteoclast Precursors and Indirectly via Osteoblast Lineage Cells
Shuting Bai , Raphael Kopan , Wei Zou , Matthew J. Hilton
Journal of Biological Chemistry 283 ( 10) 6509 -6518
258
2008
Increased intron retention is a post‐transcriptional signature associated with progressive aging and Alzheimer’s disease
Swarnaseetha Adusumalli , Zhen‐Kai Ngian , Wei‐Qi Lin , Touati Benoukraf
Aging Cell 18 ( 3)
24
2019
Enhancers: emerging roles in cell fate specification
Chin‐Tong Ong , Victor G Corces
EMBO Reports 13 ( 5) 423 -430
99
2012
NELF-A controls Drosophila healthspan by regulating heat-shock protein-mediated cellular protection and heterochromatin maintenance.
Chin-Tong Ong , Zhen-Kai Ngian , Wei-Qi Lin
Aging Cell 20 ( 5)
2021
Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability.
Chin-Tong Ong , Hui-Teng Cheng , Li-Wei Chang , Toshiyuki Ohtsuka
Journal of Biological Chemistry 281 ( 8) 5106 -5119
244
2006
Insulators as mediators of intra- and inter-chromosomal interactions: a common evolutionary theme.
Chin-Tong Ong , Victor G Corces
Journal of Biology 8 ( 8) 73 -73
20
2009
CTCF: an architectural protein bridging genome topology and function
Chin-Tong Ong , Victor G. Corces
Nature Reviews Genetics 15 ( 4) 234 -246
1,145
2014
Enhancer function: new insights into the regulation of tissue-specific gene expression
Chin-Tong Ong , Victor G. Corces
Nature Reviews Genetics 12 ( 4) 283 -293
961
2011
Poly(ADP-ribosyl)ation of OVOL2 regulates aneuploidy and cell death in cancer cells.
Rui Zhang , Jing-Jing Hong , Qiaoyun Yang , Chin-Tong Ong
Oncogene 38 ( 15) 2750 -2766
3
2019
Notch and Presenilin Regulate Cellular Expansion and Cytokine Secretion but Cannot Instruct Th1/Th2 Fate Acquisition
Chin-Tong Ong , John R. Sedy , Kenneth M. Murphy , Raphael Kopan
PLoS ONE 3 ( 7) e2823
81
2008
Insulator function and topological domain border strength scale with architectural protein occupancy.
Kevin Van Bortle , Michael H Nichols , Li Li , Chin-Tong Ong
Genome Biology 15 ( 6) 1 -18
285
2014
Modulation of CTCF Insulator Function by Transcription of a Noncoding RNA
Chin-Tong Ong , Victor G. Corces
Developmental Cell 15 ( 4) 489 -490
11
2008
Widespread rearrangement of 3D chromatin organization underlies polycomb-mediated stress-induced silencing.
Li Li , Xiaowen Lyu , Chunhui Hou , Naomi Takenaka
Molecular Cell 58 ( 2) 216 -231
226
2015
Phosphorylation of Tet3 by cdk5 is critical for robust activation of BRN2 during neuronal differentiation.
Vinay Kumar Rao , Adusumalli Swarnaseetha , Guo-Hong Tham , Wei-Qi Lin
Nucleic Acids Research 48 ( 3) 1225 -1238
3
2020
Increased intron retention is linked to Alzheimer’s disease
Chin-Tong Ong , Swarnaseetha Adusumalli
Neural Regeneration Research 15 ( 2) 259 -260
3
2020
Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment
Jennifer E. Phillips-Cremins , Michael E.G. Sauria , Amartya Sanyal , Tatiana I. Gerasimova
Cell 153 ( 6) 1281 -1295
1,180
2013
Poly(ADP-ribosyl)ation Regulates Insulator Function and Intrachromosomal Interactions in Drosophila
Chin-Tong Ong , Kevin Van Bortle , Edward Ramos , Victor G. Corces
Cell 155 ( 1) 148 -159
55
2013
CDK5-mediated phosphorylation of CP190 may regulate locomotor activity in adult female Drosophila.
Chin-Tong Ong , Wei-Qi Lin
Journal of Genetics and Genomics 45 ( 3) 177 -181
2017
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE
Marc Vooijs , Chin-Tong Ong , Brandon Hadland , Stacey Huppert
Oxford University Press for The Company of Biologists Limited 134 ( 3) 535 -544
168
2007
Truncated Tau caused by intron retention is enriched in Alzheimer’s disease cortex and exhibits altered biochemical properties
Zhen-Kai Ngian , Yow-Yong Tan , Ching-Thong Choo , Wei-Qi Lin
Proceedings of the National Academy of Sciences 119 ( 37) e2204179119 -e2204179119
15
2022