Mapping the metabolism of five amino acids in bloodstream form Trypanosoma brucei using U- 13C-labelled substrates and LC–MS

Katharina Johnston , Dong-Hyun Kim , Eduard J. Kerkhoven , Richard Burchmore
Bioscience Reports 39 ( 5)

6
2019
FALCONET: an R package to accelerate automatic visualisation of genome scale metabolic models

Hongzhong Lu , Zhengming Zhu , Eduard J Kerkhoven , Jens Nielsen
bioRxiv 662056

2019
Improving the phenotype predictions of a yeast genome‐scale metabolic model by incorporating enzymatic constraints

Benjamín J Sánchez , Cheng Zhang , Avlant Nilsson , Petri‐Jaan Lahtvee
Molecular Systems Biology 13 ( 8) 935 -935

155
2017
Trypanosoma brucei: meet the system

Fiona Achcar , Eduard J Kerkhoven , Michael P Barrett
Current Opinion in Microbiology 20 162 -169

10
2014
Regulation of amino-acid metabolism controls flux to lipid accumulation in Yarrowia lipolytica

Eduard J Kerkhoven , Kyle R Pomraning , Scott E Baker , Jens Nielsen
npj Systems Biology and Applications 2 ( 1) 16005 -16005

96
2016
Multiscale models quantifying yeast physiology: towards a whole-cell model

Hongzhong Lu , Eduard J Kerkhoven , Jens Nielsen
Trends in Biotechnology 40 ( 3) 291 -305

15
2022
Adaptations in metabolism and protein translation give rise to the Crabtree effect in yeast

Carl Malina , Rosemary Yu , Johan Björkeroth , Eduard J Kerkhoven
Proceedings of the National Academy of Sciences 118 ( 51) e2112836118

20
2021
HGTphyloDetect: facilitating the identification and phylogenetic analysis of horizontal gene transfer

Le Yuan , Hongzhong Lu , Feiran Li , Jens Nielsen
Briefings in Bioinformatics 24 ( 2) bbad035

2023
Validated growth rate-dependent regulation of lipid metabolism in Yarrowia lipolytica

Naghmeh Poorinmohammad , Jing Fu , Bob Wabeke , Eduard J Kerkhoven
International Journal of Molecular Sciences 23 ( 15) 8517

1
2022
Deep learning-based k cat prediction enables improved enzyme-constrained model reconstruction

Feiran Li , Le Yuan , Hongzhong Lu , Gang Li
Nature Catalysis 5 ( 8) 662 -672

33
2022
Improving recombinant protein production by yeast through genome-scale modeling using proteome constraints

Feiran Li , Yu Chen , Qi Qi , Yanyan Wang
Nature Communications 13 ( 1) 2969

5
2022
Multi-Omics Technologies for Optimizing Synthetic Biomanufacturing

Young-Mo Kim , Christopher J Petzold , Eduard J Kerkhoven , Scott E Baker
Frontiers in Bioengineering and Biotechnology 9 818010 -818010

2
2021
standard-GEM: standardization of open-source genome-scale metabolic models

Mihail Anton , Eivind Almaas , Rui Benfeitas , Sara Benito-Vaquerizo
bioRxiv 2023.03. 21.512712 -2023.03. 21.512712

3
2023
Probing the Metabolic Network in Bloodstream-Form Trypanosoma brucei Using Untargeted Metabolomics with Stable Isotope Labelled Glucose

Darren J Creek , Muriel Mazet , Fiona Achcar , Jana Anderson
PLOS Pathogens 11 ( 3) e1004689 -25

87
2015
The silicon trypanosome: a test case of iterative model extension in systems biology

Fiona Achcar , Abeer Fadda , Jurgen R Haanstra , Eduard J Kerkhoven
Advances in microbial physiology 64 115 -143

8
2014
Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0

Iván Domenzain , Benjamín Sánchez , Mihail Anton , Eduard J Kerkhoven
Nature communications 13 ( 1) 3766 -3766

76
2022
Generation and analysis of context-specific genome-scale metabolic models derived from single-cell RNA-Seq data

Johan Gustafsson , Mihail Anton , Fariba Roshanzamir , Rebecka Jörnsten
Proceedings of the National Academy of Sciences 120 ( 6) e2217868120 -e2217868120

19
2023
Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection

Hongzhong Lu , Feiran Li , Le Yuan , Iván Domenzain
Molecular Systems Biology 17 ( 10) e10427 -e10427

19
2021
Reconstruction, simulation and analysis of enzyme-constrained metabolic models using GECKO Toolbox 3.0

Yu Chen , Johan Gustafsson , Albert Tafur Rangel , Mihail Anton
Nature Protocols 1 -39

6
2024
Constraint-based modeling of yeast mitochondria reveals the dynamics of protein import and iron-sulfur cluster biogenesis

Carl Malina , Francesca Di Bartolomeo , Eduard J Kerkhoven , Jens Nielsen
Iscience 24 ( 11)

6
2021