Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.

Richard U. Rymer , Francisco A. Solorio , Ashley K. Tehranchi , Clement Chu
Structure 20 ( 9) 1478 -1489

56
2012
Decoding a Chain Letter for Degradation

Christian N. Cunningham , Jacob E. Corn
Structure 21 ( 7) 1068 -1070

2013
A De Novo Protein Binding Pair By Computational Design and Directed Evolution

John Karanicolas , Jacob E. Corn , Irwin Chen , Lukasz A. Joachimiak
Molecular Cell 42 ( 2) 250 -260

192
2011
Genome editing to model and reverse a prevalent mutation associated with myeloproliferative neoplasms.

Jacob E. Corn , Stacia K. Wyman , Ron Baik , Ron Baik
PLOS ONE 16 ( 3)

2021
PnB Designer: a web application to design prime and base editor guide RNAs for animals and plants.

Zacharias Kontarakis , Jacob E. Corn , Mehmet E. Karasu , Markus S. Schröder
BMC Bioinformatics 22 ( 1) 101 -101

2021
Molecular determinants of origin discrimination by Orc1 initiators in archaea

Erin C. Dueber , Alessandro Costa , Jacob E. Corn , Stephen D. Bell
Nucleic Acids Research 39 ( 9) 3621 -3631

40
2011
Hotspot-centric de novo design of protein binders.

Sarel J. Fleishman , Jacob E. Corn , Eva-Maria Strauch , Timothy A. Whitehead
Journal of Molecular Biology 413 ( 5) 1047 -1062

53
2011
Community-wide assessment of protein-interface modeling suggests improvements to design methodology

Sarel J Fleishman , Timothy A Whitehead , Eva-Maria Strauch , Jacob E Corn
Journal of Molecular Biology 414 ( 2) 289 -302

151
2011
Suppression of unwanted CRISPR-Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs

Jacob E. Corn , Dustin J. Maly , Douglas M. Fowler , John C. Rose
Nature Communications 11 ( 1) 2697 -2697

43
2020
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair.

Beeke Wienert , David N. Nguyen , Alexis Guenther , Sharon J. Feng
Nature Communications 11 ( 1) 2109

64
2020
ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules.

Andrew Leaver-Fay , Michael Tyka , Steven M. Lewis , Oliver F. Lange
Methods in Enzymology 487 545 -574

1,757
2011
Enhancer connectome in primary human cells reveals target genes of disease-associated DNA elements

Maxwell R. Mumbach , Ansuman T. Satpathy , Evan A. Boyle , Chao Dai
bioRxiv 178269

2
2017
Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms.

Behnom Farboud , Erin Jarvis , Theodore L. Roth , Jiyung Shin
Journal of Visualized Experiments 2018 ( 135) 57350

23
2018
CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells.

Jennifer E. Chung , Wendy Magis , Jonathan Vu , Seok-Jin Heo
PLOS ONE 14 ( 1) 0208237

14
2019
Cornerstones of CRISPR-Cas in drug discovery and therapy

Christof Fellmann , Benjamin G. Gowen , Pei-Chun Lin , Jennifer A. Doudna
Nature Reviews Drug Discovery 16 ( 2) 89 -100

409
2017
A prudent path forward for genomic engineering and germline gene modification

David Baltimore , Paul Berg , Michael Botchan , Dana Carroll
Science 348 ( 6230) 36 -38

385
2015
The Histone Chaperone FACT Induces Cas9 Multi-turnover Behavior and Modifies Genome Manipulation in Human Cells

Alan S. Wang , Leo C. Chen , R. Alex Wu , Yvonne Hao
Molecular Cell 79 ( 2)

12
2020
Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye.

Devin Tesar , Jacob Luoma , Emily A. Wyatt , Catherine Shi
mAbs 9 ( 8) 1297 -1305

10
2017
Genome editing via delivery of Cas9 ribonucleoprotein

Mark A. DeWitt , Jacob E. Corn , Dana Carroll
Methods 121-122 9 -15

135
2017