Kathleen R Chirco
机构: Assistant Professor, OHSU Department of Ophthalmology
每年引用次数
引用次数
引用: 897
H-指数: 12
I10-指数 : 16
出版物: 36
Monomeric C-reactive protein (mCRP) in human donor choroids: relationship with CFH genotype and effects on endothelial cell function
Miles Flamme-Wiese , Kathleen R Chirco , Robert F Mullins , Grefachew Workalemahu
Investigative Ophthalmology & Visual Science 56 ( 7) 2368 -2368
2015
The human RPE-choroid in short term organ culture: evaluation of gene expression changes
Kathleen R Chirco , Robert F Mullins , Grefachew Workalemahu , Adam P DeLuca
Investigative Ophthalmology & Visual Science 58 ( 8) 619 -619
2017
Preparation of Human Choroidal ECM Scaffolds to Study Cell Replacement Strategies
Miles Flamme-Wiese , Beatrix Ueberheide , Allison E Songstad , Kathleen R Chirco
Investigative Ophthalmology & Visual Science 58 ( 8) 4586 -4586
2017
Using CRISPR/Cas9 to achieve allele-specific editing of mutant Crx in a mouse model of Leber congenital amaurosis
Kathleen R Chirco , Deepak A Lamba , Deepak A Lamba , Jacque L Duncan
Investigative Ophthalmology & Visual Science 60 ( 9) 4956 -4956
2019
Monomeric C‐reactive protein and inflammation in age‐related macular degeneration
Kathleen R Chirco , S Scott Whitmore , Kai Wang , Lawrence A Potempa
The Journal of Pathology 240 ( 2) 173 -183
28
2016
Clinicopathological correlation in a patient with previously treated birdshot chorioretinopathy
Elliott H Sohn , Kathleen R Chirco , James C Folk , Robert F Mullins
Retinal Cases and Brief Reports 11 ( 4) 344 -347
12
2017
Development and Characterization of a Novel Choroidal Endothelial Cell Line for Studying Age-Related Macular Degeneration (Amd)
Robert F Mullins , Joseph C Giacalone , Kathleen R Chirco , Grefachew Workalemahu
MOLECULAR THERAPY 26 ( 5) 268 -268
2018
Single cell multiome analysis in 240-day old LCA7 human retinal organoids
Kathleen R Chirco , Nathaniel Kevin Mullin , Martha Neuringer , Budd A Tucker
Investigative Ophthalmology & Visual Science 64 ( 8) 2853 -2853
2023
Allele-specific gene editing to rescue dominant CRX-associated LCA7 phenotypes in a retinal organoid model
Kathleen R Chirco , Shereen Chew , Anthony T Moore , Jacque L Duncan
Stem cell reports 16 ( 11) 2690 -2702
27
2021
Timed notch inhibition drives photoreceptor fate specification in human retinal organoids
Shereen H Chew , Cassandra Martinez , Kathleen R Chirco , Sangeetha Kandoi
Investigative Ophthalmology & Visual Science 63 ( 10) 12 -12
12
2022
Immunological considerations for retinal stem cell therapy
Joshua Kramer , Kathleen R Chirco , Deepak A Lamba
Pluripotent Stem Cells in Eye Disease Therapy 99 -119
11
2019
Advancements in pre-clinical development of gene editing-based therapies to treat inherited retinal diseases
Kathleen R Chirco , Cassandra Martinez , Deepak A Lamba
Vision Research 209 108257 -108257
4
2023
Preformed Vesicle Approach to LNP Manufacturing Enhances Retinal mRNA Delivery
Yulia Eygeris , Michael I Henderson , Allison G Curtis , Antony Jozić
Small 2400815 -2400815
2024
Using human LCA7 retinal organoids to establish allele-specific editing as a therapy
Kathleen R Chirco , Shereen Chew , Anthony T Moore , Jacque L Duncan
Investigative Ophthalmology & Visual Science 63 ( 7) 81–A0054 -81–A0054
2022
Timed Notch signaling inhibition drives cone or rod photoreceptor differentiation in human retinal organoids
Shereen Hilan Chew , Cassandra Martinez , Kathleen R Chirco , Sangeetha Kandoi
Investigative Ophthalmology & Visual Science 63 ( 7) 3729–F0335 -3729–F0335
2022
Establishing an in vitro human Leber congenital amaurosis model system
Kathleen R Chirco , Shereen Chew , Jacque L Duncan , Anthony T Moore
Investigative Ophthalmology & Visual Science 62 ( 8) 1693 -1693
2021
Creating an in vitro Leber congenital amaurosis model to investigate disease mechanisms
Kathleen R Chirco , Shereen Chew , Jacque L Duncan , Anthony Moore
Investigative Ophthalmology & Visual Science 61 ( 7) 3803 -3803
2020
Structural and molecular changes in the aging choroid: implications for age-related macular degeneration
KR Chirco , EH Sohn , EM Stone , BA Tucker
Eye 31 ( 1) 10 -25
68
2017
MMP19 expression in the human optic nerve.
Kathleen R. Chirco , John H. Fingert , Robert F. Mullins , Ralph J. Hazlewood
Molecular Vision 22 ( 7) 1429 -1436
2
2016
Choroidal Endothelial cells synthesize CFH locally to protect against complement mediated injury.
Allison E. Songstad , Kathleen R. Chirco , Kelly Mulfaul , Robert F Mullins
Investigative Ophthalmology & Visual Science 60 ( 9) 1244 -1244
2019