Adam Durbin
机构: Assistant Member, Department of Oncology, St. Jude Children's Research Hospital
每年引用次数
引用次数
引用: 2,906
H-指数: 22
I10-指数 : 30
出版物: 97
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism
Achille Iolascon , Hakon Hakonarson , Adam D. Durbin , John M. Maris
PMC
267
2015
c-MYC drives a subset of high-risk pediatric neuroblastomas and is activated through mechanisms including enhancer hijacking and focal enhancer amplification
Adam D. Durbin , Mark W. Zimmerman , Brian J. Abraham , Jinghui Zhang
PMC
2018
Targeting ganglioneuromas with mTOR inhibitors.
Hui Shi , Hui Shi , A. Thomas Look , Ting Tao
Molecular and Cellular Oncology 8 ( 1) 1856621 -1856621
2021
A Resident-Led Virtual Journal Club to Educate Pediatric Residents About Coronavirus Disease 2019.
Joseph A. Majzoub , Joseph A. Majzoub , Ariel S. Winn , Ariel S. Winn
Academic Pediatrics 21 ( 4) 759 -761
2021
Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma
Teru Hideshima , Udo Oppermann , Udo Oppermann , Shannon Lauberth
Blood Cancer Discovery
12
2021
ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression
Hui Shi , Ting Tao , Brian J. Abraham , Adam D. Durbin
Science Advances 6 ( 29)
12
2020
Mechanisms underlying synergy between DNA topoisomerase I-targeted drugs and mTOR kinase inhibitors in NF1-associated malignant peripheral nerve sheath tumors.
Dong Hyuk Ki , Felix Oppel , Adam D. Durbin , A. Thomas Look
Oncogene 38 ( 39) 6585 -6598
8
2019
The CXCR4-SDF1α axis is a critical mediator of rhabdomyosarcoma metastatic signaling induced by bone marrow stroma
Brigitte Strahm , Adam D. Durbin , Elizabeth Sexsmith , David Malkin
Clinical & Experimental Metastasis 25 ( 1) 1 -10
29
2008
MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification
Mark W. Zimmerman , Yu Liu , Shuning He , Adam D. Durbin
Cancer Discovery 8 ( 3) 320 -335
147
2017
Recurrent focal copy-number changes and loss of heterozygosity implicate two noncoding RNAs and one tumor suppressor gene at chromosome 3q13.31 in osteosarcoma.
Ivan Pasic , Adam Shlien , Adam D. Durbin , Dimitrios J. Stavropoulos
Cancer Research 70 ( 1) 160 -171
132
2010
Using Chemical Epigenetics to Target Cancer
Virangika K. Wimalasena , Tingjian Wang , Logan H. Sigua , Adam D. Durbin
Molecular Cell 78 ( 6) 1086 -1095
5
2020
Expression of insulin-like growth factor pathway proteins in rhabdomyosarcoma: IGF-2 expression is associated with translocation-negative tumors.
Shalini Makawita , Michael Ho , Adam D. Durbin , Paul S. Thorner
Pediatric and Developmental Pathology 12 ( 2) 127 -135
31
2009
Abstract B22: Cell state and lineage specification are controlled by epigenetic landscapes regulating the core transcriptional regulatory circuitry in pediatric neuroblastoma
Mark W. Zimmerman , Adam D. Durbin , Brian J. Abraham , Alla Berezovskaya
Cancer Research 80
2020
Abstract B10: Rhabdomyosarcoma requires MYC family genomic events to pathogenically subvert core-regulatory circuitry
Adam D. Durbin , Guillaume Kugener , Mark W. Zimmerman , Chuan Yan
Cancer Research 80
2020
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry.
Adam D. Durbin , Mark W. Zimmerman , Neekesh V. Dharia , Brian J. Abraham
Nature Genetics 50 ( 9) 1240 -1246
65
2018
LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors.
Ting Tao , Hui Shi , Luca Mariani , Brian J. Abraham
Proceedings of the National Academy of Sciences of the United States of America 117 ( 28) 16516 -16526
6
2020
JNK1 determines the oncogenic or tumor-suppressive activity of the integrin-linked kinase in human rhabdomyosarcoma
Adam D. Durbin , Gino R. Somers , Michael Forrester , Malgorzata Pienkowska
Journal of Clinical Investigation 119 ( 6) 1558 -1570
35
2009
The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma
Myron S. Ignatius , Madeline N. Hayes , Riadh Lobbardi , Eleanor Y. Chen
Cell Reports 19 ( 11) 2304 -2318
33
2017
ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry
Lu Wang , Tze King Tan , Adam D. Durbin , Mark W. Zimmerman
Nature Communications 10 ( 1) 5622
2019
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Jasper E. Neggers , Brenton R. Paolella , Adhana Asfaw , Michael V. Rothberg
Cell Reports 33 ( 11) 108493
18
2020