Moduladores alostéricos de GSK-3 de naturaleza heterocíclica
Valle Palomo , Daniel Ignacio Pérez Fernández , Carmen Gil , María Concepción Pérez Martín
2013
1,2,4-tiadiazoles-5-imino sustituidos útiles en el tratamiento de enfermedades neurodegenerativas
José Brea Floriani , Valle Palomo , Ana Pérez Castillo , María Concepción Pérez Martín
2011
Inhibition of glycogen synthase kinase 3 prevents synaptic long-term depression and facilitates cognition in C57BL/6J mice
Tatiana V. Lipina , John C Roder , Valle Palomo , Ana Martinez
Opera Medica et Physiologica 2 ( 2) 87 -102
3
2016
Optimización de la estrategia de unión en el diseño de compuestos multidiana prometedores para el tratamiento de la enfermedad de Alzheimer
Valle Palomo , Concepción Pérez , Ana Martínez , Vanesa Nozal
Anales De La Real Academia Nacional De Farmacia 85 ( 3) 260 -273
2019
Improved linkage design for the discovery of multitarget ligands as powerful drugs for Alzheimer’s disease
Valle Palomo , Concepción Pérez , V. Nozal , Alfonso García-Rubia
Real Academia Nacional de Farmacia (España)
2019
Multitarget triazoles: an innovative approach for the treatment of Alzheimer’s disease
Valle Palomo , Concepción Pérez , Carlos Roca , V. Nozal
European Federation for Medicinal Chemistry
2019
CdSe Quantum Dots in Human Models Derived from ALS Patients: Characterization, Nuclear Penetration Studies and Multiplexing
Angeles Martín-Requero , Valle Palomo , Gracia Porras , Alberto García-Redondo
Nanomaterials 11 ( 3) 671
2021
The new iminothiadiazole derivative VP1.14 ameliorates hippocampal damage after an excitotoxic injury.
Valle Palomo , Marina Sanz-Sancristobal , Sandra Alonso-Gil , Carmen Gil
Journal of Neurochemistry 122 ( 6) 1193 -1202
6
2012
Delivery and Tracking of Quantum Dot Peptide Bioconjugates in an Intact Developing Avian Brain
Rishabh Agarwal , Miriam S. Domowicz , Nancy B. Schwartz , Judy Henry
ACS Chemical Neuroscience 6 ( 3) 494 -504
47
2015
5-Imino-1,2-4-thiadiazoles and quinazolines derivatives as glycogen synthase kinase 3β (GSK-3β) and phosphodiesterase 7 (PDE7) inhibitors: determination of blood-brain barrier penetration and binding to human serum albumin.
Daniel I. Pérez , Marco Pistolozzi , Valle Palomo , Miriam Redondo
European Journal of Pharmaceutical Sciences 45 ( 5) 677 -684
15
2012
Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis
Eva María Medina-Rodríguez , Ana Bribián , Amanda Boyd , Valle Palomo
Scientific Reports 7 ( 1) 43545 -43545
22
2017
CdSe quantum dots evaluation in primary cellular models or tissues derived from patients.
Carlota Tosat-Bitrián , Valle Palomo
Nanomedicine: Nanotechnology, Biology and Medicine 30 102299
2
2020
Glycogen synthase kinase 3 inhibition promotes adult hippocampal neurogenesis in vitro and in vivo.
Jose A. Morales-Garcia , Rosario Luna-Medina , Sandra Alonso-Gil , Marina Sanz-SanCristobal
ACS Chemical Neuroscience 3 ( 11) 963 -971
86
2012
Identification in Silico and Experimental Validation of Novel Phosphodiesterase 7 Inhibitors with Efficacy in Experimental Autoimmune Encephalomyelitis Mice
Miriam Redondo , Valle Palomo , José Brea , Daniel I. Pérez
ACS Chemical Neuroscience 3 ( 10) 793 -803
17
2012
Crosstalk between phosphodiesterase 7 and glycogen synthase kinase-3: two relevant therapeutic targets for neurological disorders.
Jose A. Morales-Garcia , Valle Palomo , Miriam Redondo , Sandra Alonso-Gil
ACS Chemical Neuroscience 5 ( 3) 194 -204
11
2014
Switching reversibility to irreversibility in glycogen synthase kinase 3 inhibitors: clues for specific design of new compounds.
Daniel I. Perez , Valle Palomo , Concepción Pérez , Carmen Gil
Journal of Medicinal Chemistry 54 ( 12) 4042 -4056
53
2011
Exploring the binding sites of glycogen synthase kinase 3. identification and characterization of allosteric modulation cavities
Valle Palomo , Ignacio Soteras , Daniel I. Perez , Concepción Perez
Journal of Medicinal Chemistry 54 ( 24) 8461 -8470
63
2011
5-imino-1,2,4-thiadiazoles: first small molecules as substrate competitive inhibitors of glycogen synthase kinase 3
Valle Palomo , Daniel I. Perez , Concepcion Perez , Jose A. Morales-Garcia
Journal of Medicinal Chemistry 55 ( 4) 1645 -1661
53
2012
Purple-, Blue-, and Green-Emitting Multishell Alloyed Quantum Dots: Synthesis, Characterization, and Application for Ratiometric Extracellular pH Sensing
Kimihiro Susumu , Lauren D. Field , Eunkeu Oh , Michael Hunt
Chemistry of Materials 29 ( 17) 7330 -7344
34
2017
Dual inhibitor of PDE7 and GSK-3 – VP1.15 acts as antipsychotic and cognitive enhancer in C57BL/6J mice
Tatiana V. Lipina , Valle Palomo , Carmen Gil , Ana Martinez
Neuropharmacology 64 ( 64) 205 -214
32
2013