引用次数
引用: 3,258
H-指数: 29
I10-指数 : 45
出版物: 99
The IκB-Protein BCL-3 Controls MAPK Activity by Promoting TPL-2 Degradation in the Nucleus
Patricia E. Collins , Domenico Somma , David Kerrigan , Felicity Herrington
bioRxiv 373209
2018
Pharmacological impact of FLT3 mutations on receptor activity and responsiveness to tyrosine kinase inhibitors.
Vanessa Marensi , Karen R. Keeshan , David J. MacEwan
Biochemical Pharmacology 183 114348 -114348
1
2021
Diagnostic and Therapeutic Utility of Tribbles-2 in Human Cancers
Warren S. Pear , Karen Keeshan , Yiping He
1
2011
TRIB2 Transformed GMP is the Myeloid Leukaemia Initiating Cell
Karen Keeshan , Krishna Yalla , Caitriona O'Connor , Joana Campos
2016
TRIB2 Regulates the Cell Cycle Under Stress Conditions in a Murine Cell Model of Leukaemia
Karen Keeshan , Mara Salomè
2016
A Synthetic Lethal Approach to Eradicate AML Via Synergistic Activation of Pro-Apoptotic p53 By MDM2 and BET Inhibitors
Tessa L. Holyoake , Karen Keeshan , Timothy Chevassut , Mhairi Copland
Blood 136 14 -14
2020
Functional SCD1 Is Critical for Acute Lymphoblastic Leukaemia Maintenance in the Central Nervous System
Karen Keeshan , Pawel Herzyk , Sergey Tumanov , Jurre Kamphorst
Blood 130 2608 -2608
2017
BRD4-mediated repression of p53 is a target for combination therapy in AML
Tessa Holyoake , Karen Keeshan , Timothy J T Chevassut , Kathryn Gilroy
Nature Communications 12 ( 1) 241
30
2021
Superenhancing AML with Trib1
Karen Keeshan
Blood 137 ( 1) 8 -9
2021
Insights into the molecular profiles of adult and paediatric acute myeloid leukaemia.
Karen Keeshan , Joana Bittencourt‐Silvestre , Megan L. Mills , Myint Myat Khine Aung
Molecular Oncology
2021
Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease
Patrick A. Eyers , Karen Keeshan , Natarajan Kannan
Trends in Cell Biology 27 ( 4) 284 -298
88
2017
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias
Shahzya Chaudhury , Caitríona O’Connor , Ana Cañete , Joana Bittencourt-Silvestre
Nature Communications 9 ( 1) 5280 -5280
16
2018
Regulation of NF-κB by PML and PML-RARα
Abrar Ahmed , Xiaochun Wan , Izaskun Mitxitorena , Andrew J. Lindsay
Scientific Reports 7 ( 1) 44539
8
2017
Leukemogenesis induced by wild type and STI571-resistant BCR/ABL is potently suppressed by C/EBPα.
Giovanna Ferrari-Amorotti , Karen Keeshan , Michela Zattoni , Clara Guerzoni
Blood 108 ( 4) 1353 -1362
35
2006
Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation
Loveena Rishi , Maura Hannon , Mara Salomè , Marie Hasemann
Blood 123 ( 15) 2389 -2400
40
2014
Tribbles in acute leukemia
Kai Ling Liang , Loveena Rishi , Karen Keeshan
Blood 121 ( 21) 4265 -4270
40
2013
Dual inhibition of MDM2 and BET cooperate to eradicate acute myeloid leukemia
Anne-Louise Latif , John J Cole , Joana Monteiro Campos , William Clark
Blood 126 ( 23) 674 -674
2
2015
The Bone Marrow Niche Distinguishes Young and Old Leukemia
Shahzya S Chaudhury , Helen Wheadon , Brenda Gibson , Karen Keeshan
Blood 128 ( 22) 1548 -1548
2016
TRIB2 regulates normal and stress-induced thymocyte proliferation
Kai Ling Liang , Caitriona O’Connor , J Pedro Veiga , Tommie V McCarthy
Cell discovery 2 ( 1) 15050 -15050
27
2016
The functionally diverse roles of tribbles.
Fiona Lohan , Karen Keeshan
Biochemical Society Transactions 41 ( 4) 1096 -1100
52
2013