Ian J Groves
机构: Assistant Professor, Cleveland Clinic Lerner College of Medicine
每年引用次数
引用次数
引用: 1,500
H-指数: 19
I10-指数 : 25
出版物: 50
HPV16 oncogene expression levels during early cervical carcinogenesis are determined by the balance of epigenetic chromatin modifications at the integrated virus genome
I J Groves , E L A Knight , Q Y Ang , C G Scarpini
Oncogene 35 ( 36) 4773 -4786
18
2016
Bromodomain proteins regulate human cytomegalovirus latency and reactivation allowing epigenetic therapeutic intervention
Rab K Prinjha , Mark R Wills , Ian J Groves , Michal Schwartz
Proceedings of the National Academy of Sciences of the United States of America 118 ( 9)
16
2021
Latent Cytomegalovirus-Driven Recruitment of Activated CD4+ T Cells Promotes Virus Reactivation.
Charlotte J Houldcroft , Mark R Wills , Ian J Groves , John H Sinclair
Frontiers in Immunology 12 657945
2021
A BMPR2/YY1 Signaling Axis Is Required for Human Cytomegalovirus Latency in Undifferentiated Myeloid Cells.
Mark Wills , Ian J Groves , Maria Cristina Carlan da Silva , John Sinclair
Mbio
2021
Increased Epstein-Barr virus C-promoter activity with CTCF-binding site deletion is associated with elevated EBNA2 recruitment.
Ian J Groves , Martin J Allday
bioRxiv 442186
2018
Depletion of polycistronic transcripts using short interfering RNAs: cDNA synthesis method affects levels of non-targeted genes determined by quantitative PCR.
Jennifer E Hanning , Ian J Groves , Mark R Pett , Nicholas Coleman
Virology Journal 10 ( 1) 159 -159
5
2013
Depletion of HPV16 early genes induces autophagy and senescence in a cervical carcinogenesis model, regardless of viral physical state
Jennifer E Hanning , Harpreet K Saini , Matthew J Murray , Maria M Caffarel
The Journal of Pathology 231 ( 3) 354 -366
27
2013
Virus transcript levels and cell growth rates after naturally occurring HPV16 integration events in basal cervical keratinocytes.
Cinzia G Scarpini , Ian J Groves , Mark R Pett , Dawn Ward
The Journal of Pathology 233 ( 3) 281 -293
16
2014
Pathogenesis of human papillomavirus‐associated mucosal disease
Ian J Groves , Nicholas Coleman
The Journal of Pathology 235 ( 4) 527 -538
160
2015
Human papillomavirus genome integration in squamous carcinogenesis: what have next-generation sequencing studies taught us?
Ian J Groves , Nicholas Coleman
The Journal of Pathology 245 ( 1) 9 -18
20
2018
Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies
Timo WM De Groof , Elizabeth G Elder , Eleanor Y Lim , Raimond Heukers
Nature Communications 12 ( 1) 4436
14
2021
Short-and long-range cis interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis
Ian J Groves , Emma LA Drane , Marco Michalski , Jack M Monahan
PLoS pathogens 17 ( 8) e1009875 -e1009875
23
2021
Cytomegalovirus US28 regulates cellular EphA2 to maintain viral latency
Amanda B Wass , Benjamin A Krishna , Laura E Herring , Thomas SK Gilbert
Science Advances 8 ( 43) eadd1168 -eadd1168
7
2022
CTCF association with episomal HPV16 genomes regulates viral oncogene transcription and splicing
Ian J Groves , George Tang , Ieisha Pentland , Joanna L Parish
bioRxiv
2021
Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naive B cells, and facilitates recruitment of transcription factors to the viral genome
Agnieszka Szymula , Richard D Palermo , Amr Bayoumy , Ian J Groves
PLoS pathogens 14 ( 2) e1006890 -e1006890
63
2018
Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naive B cells, and facilitates recruitment of transcription factors to the viral genome (vol 14, e1006890, 2018)
Agnieszka Szymula , Richard D Palermo , Amr Bayoumy , Ian J Groves
PLOS PATHOGENS 15 ( 2)
2019
Disruption of CTCF-YY1–dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcription
Ieisha Pentland , Karen Campos-León , Marius Cotic , Kelli-Jo Davies
PLOS Biology 16 ( 10) e2005752
29
2018
Chromatin control of human cytomegalovirus infection
Stephen M Matthews , Ian J Groves , Christine M O'Connor
Mbio 14 ( 4) e00326 -23
6
2023
Host-encoded CTCF regulates human cytomegalovirus latency via chromatin looping
Ian J Groves , Stephen M Matthews , Christine M O’Connor
Proceedings of the National Academy of Sciences 121 ( 10) e2315860121 -e2315860121
3
2024
Loopy virus or controlled contortionist? 3D regulation of HCMV gene expression by CTCF-driven chromatin interactions
Ian J Groves , Christine M O’Connor
Journal of Virology e01148 -24
2024