引用次数
引用: 22,886
H-指数: 68
I10-指数 : 128
出版物: 346
Head-to-Head Evaluation of 18F-FES and 18F-FDG PET/CT in Metastatic Invasive Lobular Breast Cancer.
Gary A. Ulaner , Komal Jhaveri , Sarat Chardarlapaty , Vaios Hatzoglou
The Journal of Nuclear Medicine 62 ( 3) 326 -331
37
2021
Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis.
Sunyana Gadal , Andre Levchenko , Neal Rosen , Sarat Chandarlapaty
Molecular Cell 81 ( 4)
3
2021
Unlocking the potential of antibody-drug conjugates for cancer therapy.
Sarat Chandarlapaty , Sarat Chandarlapaty , Shanu Modi , Shanu Modi
Nature Reviews Clinical Oncology 18 ( 6) 327 -344
299
2021
Abstract PD8-08: A phase 1/2 study of SAR439859, an oral selective estrogen receptor (ER) degrader (SERD), as monotherapy and in combination with other anti-cancer therapies in postmenopausal women with ER-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer (mBC): AMEERA-1
Mario Campone , Aditya Bardia , Gary A Ulaner , Sarat Chandarlapaty
Cancer Research 81
2021
Genomic Alterations in PIK3CA-Mutated Breast Cancer Result in mTORC1 Activation and Limit the Sensitivity to PI3Kα Inhibitors.
Maurizio Scaltriti , Jorge S. Reis-Filho , Pau Castel , Sarat Chandarlapaty
Cancer Research 81 ( 9) 2470 -2480
2021
Clinical Experience of Cerebrospinal Fluid-Based Liquid Biopsy Demonstrates Superiority of Cell-Free DNA over Cell Pellet Genomic DNA for Molecular Profiling.
Mark G. Kris , Matthias A. Karajannis , Ingo Mellinghoff , Igor Gavrilovic
The Journal of Molecular Diagnostics 23 ( 6) 742 -752
2021
Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer.
Funda Meric-Bernstam , Udai Banerji , Gerald Batist , Elza C de Bruin
NPJ breast cancer 7 ( 1) 44 -44
11
2021
TERT promoter hotspot mutations and gene amplification in metaplastic breast cancer
Britta Weigelt , Jorge S Reis-Filho , Sarat Chandarlapaty , Edi Brogi
npj Breast Cancer 7 ( 1) 43 -43
2021
A Phase I study of alpelisib in combination with trastuzumab and LJM716 in patients with PIK3CA-mutated HER2-positive metastatic breast cancer.
Neal Rosen , Sarat Chandarlapaty , Shanu Modi , Komal Jhaveri
Clinical Cancer Research
2021
Independent real-world application of a clinical-grade automated prostate cancer detection system.
Carlos Gil Ferreira , Emilio M Pereira , Jillian Sue , Christopher Kanan
The Journal of Pathology 254 ( 2) 147 -158
2021
Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer.
Emad Tajkhorshid , Benita S. Katzenellenbogen , John A. Katzenellenbogen , Weiyi Toy
Molecular Cancer Research
2021
AKT Inhibition in Solid Tumors With AKT1 Mutations
David M. Hyman , Lillian M. Smyth , Mark T.A. Donoghue , Shannon N. Westin
Journal of Clinical Oncology 35 ( 20) 2251 -2259
243
2017
Correlation of PIK3CA mutations in cell-free DNA (cfDNA) and efficacy of everolimus (EVE) in metastatic breast cancer: Results from BOLERO-2.
Francois Philippe Ringeisen , Gabriel N. Hortobagyi , Jose Baselga , Sarat Chandarlapaty
Journal of Clinical Oncology 34 ( 15_suppl) 519 -519
5
2016
HER2-amplified breast cancer: mechanisms of trastuzumab resistance and novel targeted therapies
Devika Gajria , Sarat Chandarlapaty
Expert Review of Anticancer Therapy 11 ( 2) 263 -275
500
2011
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors.
Neil Vasan , Pedram Razavi , Jared L. Johnson , Hong Shao
Science 366 ( 6466) 714 -723
161
2019
Feasibility, safety, and efficacy of aerobic training in pretreated patients with metastatic breast cancer: A randomized controlled trial.
Jessica M. Scott , Neil M. Iyengar , Tormod S. Nilsen , Meghan Michalski
Cancer 124 ( 12) 2552 -2560
32
2018
AKT Inhibition Relieves Feedback Suppression of Receptor Tyrosine Kinase Expression and Activity
Sarat Chandarlapaty , Ayana Sawai , Maurizio Scaltriti , Vanessa Rodrik-Outmezguine
Cancer Cell 19 ( 1) 58 -71
1,015
2011
Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer
Brett S. Carver , Caren Chapinski , John Wongvipat , Haley Hieronymus
Cancer Cell 19 ( 5) 575 -586
1,211
2011
Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas
Piro Lito , Christine A. Pratilas , Eric W. Joseph , Madhavi Tadi
Cancer Cell 22 ( 5) 668 -682
546
2012
Abstract OT1-04-05: Phase 1/2 dose-escalation and expansion study investigating SAR439859, a potent, oral, selective estrogen receptor degrader, +/- palbociclib in metastatic breast cancer
Mario Campone , Aditya Bardia , Gary A Ulaner , Sarat Chandarlapaty
Cancer Research 80
2020