Charles Sawyers
机构: Memorial Sloan Kettering Cancer Center
每年引用次数
引用次数
引用: 125,104
H-指数: 139
I10-指数 : 332
出版物: 673
2043 Mechanisms of therapeutic synergy between radiation treatment and adenoviral gene therapy with the replication competent PSA-specific vector CN706 in the LAPC-4 and LnCaP prostate cancer cell lines
N.R. Ramakrishna , N. Rioseco-Camacho , C.L. Sawyers , D.C. Yu
International Journal of Radiation Oncology Biology Physics 45 ( 3) 300
1999
GENETIC APPROACHES TO DEFINING SIGNALING BY THE CML-ASSOCIATED TYROSINE KINASE BCR-ABL
D.E.H. Afar , A. Goga , L. Cohen , C.L. Sawyers
Cold Spring Harbor Symposia on Quantitative Biology 59 589 -594
10
1994
Towards a global cancer knowledge network: dissecting the current international cancer genomic sequencing landscape.
D.J. Vis , J. Lewin , R.G. Liao , M. Mao
Annals of Oncology 28 ( 5) 1145 -1151
9
2017
p53 dependent growth suppression by the c-Abl nuclear tyrosine kinase.
C. L. Sawyers , A. Goga , O. N. Witte , T. M. Hambuch
Oncogene 11 ( 4) 791 -799
122
1995
Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia
K. Shuai , J. Ten Hoeve , C. L. Sawyers , J. Halpern
Oncogene 13 ( 2) 247 -254
580
1996
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia: Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lympoblastic leukemia with the philadelphia chromosome
Geoffrey Zubay , C. L. Sawyers , Hagop M Kantarjian , S. Ohno-Jones
Chemtracts 14 ( 13) 733 -738
12
2001
Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction.
C. L. Sawyers , L. Timson , E. S. Kawasaki , S. S. Clark
Proceedings of the National Academy of Sciences of the United States of America 87 ( 2) 563 -567
123
1990
Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
P. A. Watson , Y. F. Chen , M. D. Balbas , J. Wongvipat
Proceedings of the National Academy of Sciences of the United States of America 107 ( 39) 16759 -16765
707
2010
Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
C. Tran , S. Ouk , N. J. Clegg , Y. Chen
Science 324 ( 5928) 787 -790
2,425
2009
Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases
T. A. Carter , L. M. Wodicka , N. P. Shah , A. M. Velasco
Proceedings of the National Academy of Sciences of the United States of America 102 ( 31) 11011 -11016
543
2005
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
X. Wu , K. Senechal , M. S. Neshat , Y. E. Whang
Proceedings of the National Academy of Sciences of the United States of America 95 ( 26) 15587 -15591
859
1998
Identification of an Oncogenic RAB Protein
D. B. Wheeler , R. Zoncu , D. E. Root , D. M. Sabatini
Science 350 ( 6257) 211 -217
78
2015
A Model for Predicting Nephrotoxicity in Patients Treated with Aminoglycosides
C. L. Sawyers , R. D. Moore , S. A. Lerner , C. R. Smith
The Journal of Infectious Diseases 153 ( 6) 1062 -1068
79
1986
Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance.
M. R. Burgess , B. J. Skaggs , N. P. Shah , F. Y. Lee
Proceedings of the National Academy of Sciences of the United States of America 102 ( 9) 3395 -3400
299
2005
A phase I study of BMS-354825 in patients with imatinib-resistant and intolerant accelerated and blast phase chronic myeloid leukemia (CML): Results from CA180002
C. L. Sawyers , N. P. Shah , H. M. Kantarjian , J. Cortes
Journal of Clinical Oncology 23 6520 -6520
33
2005
Correlation of clinical response to BMS-354825 with BCR-ABL mutation status in imatinib-resistant patients with chronic myeloid leukemia (CML) and Philadelphia chromosome-associated acute lymphoblastic leukemia (Ph+ ALL)
N. Shah , C. L. Sawyers , H. M. M. Kantarjian , N. Donato
Journal of Clinical Oncology 23 6521 -6521
9
2005
A phase I study of BMS-354825 in patients with imatinib-resistant and intolerant chronic phase chronic myeloid leukemia (CML): Results from CA180002
M. Talpaz , H. M. Kantarjian , R. Paquette , N. Shah
Journal of Clinical Oncology 23 6519 -6519
35
2005
Imaging Tumor Burden in the Brain with 89Zr-Transferrin
M. J. Evans , J. P. Holland , S. L. Rice , M. G. Doran
The Journal of Nuclear Medicine 54 ( 1) 90 -95
31
2013
Isolation of unknown genes from human bone marrow by differential screening and single-pass cDNA sequence determination.
S. L. Orr , T. P. Hughes , C. L. Sawyers , R. M. Kato
Proceedings of the National Academy of Sciences of the United States of America 91 ( 25) 11869 -11873
14
1994
Research on Resistance to Cancer Drug Gleevec
C. L. Sawyers
Science 294 ( 5548) 1834b -1834
41
2001