C-terminal mutation induces a folding defect in the serotonin transporter

Ali Elkasaby , Subhodeep Sarker , Herwig Just
BMC Pharmacology 8 ( 1) 1 -1

2008
An Ionic Lock Between Intracellular Loop 1 and a C‐terminal Amphipathic Helix Stabilizes the Serotonin Transporter Along its Folding Trajectory

Sonja Sucic , Ali El‐Kasaby , Florian Koban , Michael Freissmuth
The FASEB Journal 29 566.11 -566.11

2015
Probing binding and occlusion of substrate in the human creatine transporter‐1 by computation and mutagenesis

Amy Clarke , Clemens V Farr , Ali El‐Kasaby , Daniel Szöllősi
Protein Science: a Publication of the Protein Society 33 ( 1)

2024
Rescueing sleepless flies–Pharmacochaperoning of folding-deficient dopamine transporters, which give rise to infantile dystonia/Parkinsonism

M Freissmuth , A El-Kasaby , A Kasture , HMM Asjad
Acta Neurobiologiae Experimentalis 77 ( Suppl. 1)

2017
1
2018
Dopamine 2016

Carina KERN , Fatma Aslı ERDEM , Ali EL-KASABY , Walter SANDTNER

2016
24th Scientific Symposium of the Austrian Pharmacological Society

Sonja SUCIC , Ali EL-KASABY , Michael FREISSMUTH

Binding and neutralization of C. difficile toxins A and B by purified clinoptilolite-tuff.

Michael Freissmuth , Ali El-Kasaby , Carmen Ranftler , Florian Koban
PLOS ONE 16 ( 5)

2021
Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.

Ali El-Kasaby , Herwig Just , Elisabeth Malle , Peggy C. Stolt-Bergner
Journal of Biological Chemistry 285 ( 50) 39201 -39210

52
2010
The role of the carboxyl terminus in folding of the serotonin transporter

Ali El-Kasaby , Herwig Just , Harald Sitte , Oliver Kudlacek
BMC Pharmacology 10 ( 1) 1 -2

2010
Concentrative ER export of the serotonin transporter relies exclusively on an interaction with Sec24C

Sonja Sucic , Ali El-Kasaby , Subhodeep Sarker , Harald H Sitte
BMC Pharmacology 10 ( 1) 1 -1

2010
ABC transporters of Fasciola hepatica as putative drug targets

Ali El-Kasaby , Thomas Stockner , Oliver Kudlacek
BMC Pharmacology 11 ( 2) 1 -1

2011
2009
How does the carboxyl terminus assist folding and ER export of the serotonin transporter

Ali El-Kasaby , Florian Koban , Michael Freissmuth , Sonja Sucic
BMC Clinical Pharmacology 13 ( 1) 1 -1

2012
Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome.

Ali El-Kasaby , Ameya Kasture , Florian Koban , Matej Hotka
Neuropharmacology 161 107572

7
2019
Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits.

Shreyas Bhat , Ali El-Kasaby , Michael Freissmuth , Sonja Sucic
Pharmacology & Therapeutics 222 107785 -107785

2
2021
A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter.

Florian Koban , Ali El-Kasaby , Cornelia Häusler , Thomas Stockner
Journal of Biological Chemistry 290 ( 21) 13263 -13278

32
2015