ENGINEERED ANTI-IL-23p19 ANTIBODIES

Brian M. Beyer , Richard N. Ingram , Leonard G. Presta , Peter Orth

146
2008
56
2005
Über Nutzen und Perspektiven eines gedruckten Initien-Verzeichnisses

Peter Orth
Deutsches Archiv für Erforschung des Mittelalters 63 ( 1) 125 -134

2007
Structural optimization of cyclic sulfonamide based novel HIV-1 protease inhibitors to picomolar affinities guided by X-ray crystallographic analysis

Ashit K. Ganguly , Sesha S. Alluri , Chih-Hung Wang , Alyssa Antropow
Tetrahedron 70 ( 18) 2894 -2904

20
2014
Der Tetracyclin‐Repressor – das Musterbeispiel für einen biologischen Schalter

Wolfram Saenger , Peter Orth , Caroline Kisker , Wolfgang Hillen
Angewandte Chemie 112 ( 12) 2122 -2133

6
2000
Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.

Wolfram Saenger , Winfried Hinrichs , Peter Orth , Dirk Schnappinger
Nature Structural & Molecular Biology 7 ( 3) 215 -219

380
2000
Fused bi-heteroaryl substituted hydantoin compounds as TACE inhibitors

Ling Tong , Seong Heon Kim , Kristin Rosner , Wensheng Yu
Bioorganic & Medicinal Chemistry Letters 27 ( 14) 3037 -3042

4
2017
The Tetracycline Repressor-A Paradigm for a Biological Switch.

Wolfram Saenger , Peter Orth , Caroline Kisker , Wolfgang Hillen
Angewandte Chemie 39 ( 12) 2042 -2052

105
2000
Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibody

Brian M. Beyer , Richard Ingram , Lata Ramanathan , Paul Reichert
Journal of Molecular Biology 382 ( 4) 942 -955

63
2008
Correction to Design, Synthesis, and X-ray Crystallographic Analysis of a Novel Class of HIV-1 Protease Inhibitors

Ashit K. Ganguly , Sesha S. Alluri , Danielle Caroccia , Dipshikha Biswas
Journal of Medicinal Chemistry 55 ( 11) 5647 -5647

2012
Design, synthesis, and X-ray crystallographic analysis of a novel class of HIV-1 protease inhibitors.

Sesha S. Alluri , Danielle Caroccia , Dipshikha Biswas , Chih-Hung Wang
Journal of Medicinal Chemistry 54 ( 20) 7176 -7183

38
2011
Specific binding of divalent metal ions to tetracycline and to the Tet repressor/tetracycline complex.

Gottfried J. Palm , Thomas Lederer , Peter Orth , Wolfram Saenger
Journal of Biological Inorganic Chemistry 13 ( 7) 1097 -1110

51
2008
Novel TNF-α converting enzyme (TACE) inhibitors as potential treatment for inflammatory diseases

Vinay M. Girijavallabhan , Lei Chen , Chaoyang Dai , Robert J. Feltz
Bioorganic & Medicinal Chemistry Letters 20 ( 24) 7283 -7287

18
2010
Design and synthesis of potent Gram-negative specific LpxC inhibitors.

U. Faruk Mansoor , Dilrukshi Vitharana , Panduranga Adulla Reddy , Dayna L. Daubaras
Bioorganic & Medicinal Chemistry Letters 21 ( 4) 1155 -1161

40
2011
2-(2-Aminothiazol-4-yl)pyrrolidine-based tartrate diamides as potent, selective and orally bioavailable TACE inhibitors.

Chaoyang Dai , Dansu Li , Janeta Popovici-Muller , Lianyun Zhao
Bioorganic & Medicinal Chemistry Letters 21 ( 10) 3172 -3176

17
2011
Structure and activity relationships of tartrate-based TACE inhibitors.

Dansu Li , Janeta Popovici-Muller , David B Belanger , John Caldwell
Bioorganic & Medicinal Chemistry Letters 20 ( 16) 4812 -4815

10
2010
Biaryl substituted hydantoin compounds as TACE inhibitors

Aneta Kosinski , Razia Rizvi , Dansu Li , Robert J. Feltz
Bioorganic & Medicinal Chemistry Letters 20 ( 17) 5286 -5289

22
2010
Crystallization and preliminary X-ray analysis of the acyl carrier protein synthase (AcpS) from Staphylococcus aureus.

Dayna L. Daubaras , Eileen M. Wilson , Todd Black , Corey Strickland
Acta Crystallographica Section D-biological Crystallography 60 ( 4) 773 -774

2
2004
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates

Mihirbaran Mandal , Yusheng Wu , Jeffrey Misiaszek , Guoqing Li
Journal of Medicinal Chemistry 59 ( 7) 3231 -3248

24
2016