Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis.

Diana Jurk , Derek A. Mann , Michele Vacca , João F. Passos
Journal of Immunology 206 ( 4) 904 -916

17
2021
Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice

Thomas von Zglinicki , Tamar Pirtskhalava , Nathan K. LeBrasseur , Diana Jurk
Aging Cell 20 ( 2)

115
2021
Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner.

Mathias Heikenwalder , Petra Hirsova , Thomas von Zglinicki , Kevin D Pavelko
The EMBO Journal 40 ( 9)

52
2021
Telmisartan prevents high-fat diet-induced neurovascular impairments and reduces anxiety-like behavior.

Olga Will , Urte Matschl , Gianna Huber , Lukas Huber
Journal of Cerebral Blood Flow and Metabolism

1
2021
Quantitative assessment of markers for cell senescence.

Conor Lawless , Chunfang Wang , Diana Jurk , Alina Merz
Experimental Gerontology 45 ( 10) 772 -778

178
2010
A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations

Conor Lawless , Diana Jurk , Colin S. Gillespie , Daryl Shanley
PLoS ONE 7 ( 2) e32117

45
2012
SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair

Graeme Hewitt , Bernadette Carroll , Rezazadeh Sarallah , Clara Correia-Melo
Autophagy 12 ( 10) 1917 -1930

73
2016
Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis.

Bernadette Carroll , Elsje G. Otten , Diego Manni , Rhoda Stefanatos
Nature Communications 9 ( 1) 256 -256

81
2018
Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

Maria Grazia Vizioli , Tianhui Liu , Karl N Miller , Neil A Robertson
Genes & Development 34 ( 5) 428 -445

142
2020
A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

Mariana G. Tarragó , Claudia C.S. Chini , Karina S. Kanamori , Gina M. Warner
Cell Metabolism 27 ( 5) 1081 -1095.e10

94
2018
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

Mikolaj Ogrodnik , Yi Zhu , Larissa G.P. Langhi , Tamar Tchkonia
Cell Metabolism 29 ( 5) 1233

305
2019
Length-independent telomere damage drives cardiomyocyte senescence

Rhys Anderson , Anthony Lagnado , Damien Maggiorani , Anna Walaszczyk
bioRxiv 394809

2018
Senolytics improve physical function and increase lifespan in old age

Ming Xu , Tamar Pirtskhalava , Joshua N. Farr , Bettina M. Weigand
Nature Medicine 24 ( 8) 1246 -1256

1,190
2018
Sustained telomere length in hepatocytes and cholangiocytes with increasing age in normal liver

Suman Verma , Phaedra Tachtatzis , Sue Penrhyn-Lowe , Cinzia Scarpini
Hepatology 56 ( 4) 1510 -1520

41
2012
Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice

Carolyn M. Roos , Bin Zhang , Allyson K. Palmer , Mikolaj B. Ogrodnik
Aging Cell 15 ( 5) 973 -977

539
2016
Rapamycin improves healthspan but not inflammaging in nfκb1−/− mice

Clara Correia-Melo , Jodie Birch , Edward Fielder , Dina Rahmatika
Aging Cell 18 ( 1)

21
2019
Targeting senescent cells alleviates obesity‐induced metabolic dysfunction

Allyson K Palmer , Ming Xu , YI Zhu , Tamar Pirtskhalava
Aging Cell 18 ( 3) 12950

322
2019
Amelioration of age-related brain function decline by Bruton's tyrosine kinase inhibition.

Akang E. Ekpenyong‐Akiba , Marta Poblocka , Mohammad Althubiti , Miran Rada
Aging Cell 19 ( 1) 1 -11

11
2020
Anti-inflammatory treatment rescues memory deficits during aging in nfkb1−/− mice

Edward Fielder , Clare Tweedy , Caroline Wilson , Fiona Oakley
Aging Cell 19 ( 10)

3
2020
DNA damage response and cellular senescence in tissues of aging mice

Chunfang Wang , Diana Jurk , Mandy Maddick , Glyn Nelson
Aging Cell 8 ( 3) 311 -323

673
2009