Digestibility of resistant starch type 3 is affected by crystal type, molecular weight and molecular weight distribution.
J.H. Bitter , P.L. Buwalda , C.E. Klostermann , H.A. Schols
Carbohydrate Polymers 265 118069
2021
New genotype-phenotype linkages for directed evolution of functional proteins
H LEEMHUIS , V STEIN , A GRIFFITHS , F HOLLFELDER
Current Opinion in Structural Biology 15 ( 4) 472 -478
154
2005
Patent 2761257 Summary
LUBBERT DIJKHUIZEN , JOHANNIS PAULUS KAMERLING , REINDER JOHANNES LEEMHUIS , SLAVKO KRALJ
Glucooligosaccharides comprising (alpha 1-> 4) and (alpha 1-> 6) glycosidic bonds, use thereof, and methods for providing them
L. Dijkhuizen , M.J.E.C. van der Maarel , J.P. Kamerling , R.J. Leemhuis
18
2017
Fiber supplemented acidified dairy products and methods for providing the same
A.A.C.M. Oudhuis , R.J. Leemhuis , P.L. Buwalda
2023
Characterization of a GH57 4-α-glucanotransferase from a thermophilic archaeal strain with potential for alkyl glycosides production.
Justyna Dobruchowska , Linda Önnby , Lubbert Dijkhuizen , Catherine Paul
Applied Microbiology and Biotechnology
2015
Evolution toward small molecule inhibitor resistance affects native enzyme function and stability, generating acarbose-insensitive cyclodextrin glucanotransferase variants
Ronan M. Kelly , Hans Leemhuis , Linda Gätjen , Lubbert Dijkhuizen
Journal of Biological Chemistry 283 ( 16) 10727 -10734
10
2008
Directed evolution of a histone acetyltransferase – enhancing thermostability, whilst maintaining catalytic activity and substrate specificity
Hans Leemhuis , Karl P. Nightingale , Florian Hollfelder
FEBS Journal 275 ( 22) 5635 -5647
9
2008
The evolution of cyclodextrin glucanotransferase product specificity
Ronan M. Kelly , Lubbert Dijkhuizen , Hans Leemhuis
Applied Microbiology and Biotechnology 84 ( 1) 119 -133
84
2009
Engineering of cyclodextrin glucanotransferases and the impact for biotechnological applications.
Hans Leemhuis , Ronan M. Kelly , Lubbert Dijkhuizen
Applied Microbiology and Biotechnology 85 ( 4) 823 -835
204
2010
Hydrolysis and Transglycosylation Reaction Specificity of Cyclodextrin Glycosyltransferases
Hans Leemhuis , Lubbert Dijkhuizen
Journal of applied glycoscience 50 ( 2) 263 -271
6
2003
4,6-α-Glucanotransferase activity occurs more widespread in Lactobacillus strains and constitutes a separate GH70 subfamily
Hans Leemhuis , Willem P. Dijkman , Justyna M. Dobruchowska , Tjaard Pijning
Applied Microbiology and Biotechnology 97 ( 1) 181 -193
36
2013
A GH57 4-α-glucanotransferase of hyperthermophilic origin with potential for alkyl glycoside production.
Catherine J. Paul , Hans Leemhuis , Justyna M. Dobruchowska , Carl Grey
Applied Microbiology and Biotechnology 99 ( 17) 7101 -7113
7
2015
Crystal Structure of Inulosucrase from Lactobacillus: Insights Into the Substrate Specificity and Product Specificity of Gh68 Fructansucrases.
Tjaard Pijning , Munir A. Anwar , Markus Böger , Justyna M. Dobruchowska
Journal of Molecular Biology 412 ( 1) 80 -93
68
2011
Directed evolution of enzymes: Library screening strategies.
Hans Leemhuis , Ronan M. Kelly , Lubbert Dijkhuizen
Iubmb Life 61 ( 3) 222 -228
164
2009
Characterization of the Gene Cluster Involved in Isoprene Metabolism in Rhodococcus sp. Strain AD45
Johan E. T. van Hylckama Vlieg , Hans Leemhuis , Jeffrey H. Lutje Spelberg , Dick B. Janssen
Journal of Bacteriology 182 ( 7) 1956 -1963
69
2000
Conversion of cyclodextrin glycosyltransferase into a starch hydrolase by directed evolution: the role of alanine 230 in acceptor subsite +1.
Hans Leemhuis , Henriëtte J. Rozeboom , Maarten Wilbrink , Gert-Jan W. Euverink
Biochemistry 42 ( 24) 7518 -7526
74
2003
Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution
Ronan M. Kelly , Hans Leemhuis , Henriëtte J. Rozeboom , Niels van Oosterwijk
Biochemical Journal 413 ( 3) 517 -525
45
2008
The role of conserved inulosucrase residues in the reaction and product specificity of Lactobacillus reuteri inulosucrase
Munir A. Anwar , Hans Leemhuis , Tjaard Pijning , Slavko Kralj
FEBS Journal 279 ( 19) 3612 -3621
16
2012
Characterization of the GH13 and GH57 glycogen branching enzymes from Petrotoga mobilis SJ95 and potential role in glycogen biosynthesis.
Xuewen Zhang , Hans Leemhuis , Marc J. E. C. van der Maarel
PLOS ONE 14 ( 7)
2
2019
L. Dijkhuizen Bauke Dijkstra Marc Van der Maarel Justyna M. Dobruchowska, Ph.D. Joost Uitdehaag Sander S. van Leeuwen Munir Ahmad Anwar buwalda, p. Florian Hollfelder G.J. Gerwig karl nightingale Gert-Jan Euverink paul de vos Viktor Stein Katja Loos Antoni Planas Dick B. Janssen J.E.T van Hylckama Vlieg Jeffrey Lutje Spelberg Willem P. Dijkman