Site-Directed Spin Labeling Studies of Nucleic Acid Dependent Conformational Changes in CRISPR-Cas9

Carolina Vazquez Reyes , Peter Zhifeng Qin
Biophysical Journal 110 ( 3)

2016
Site-specific labeling of RNA with fluorophores and other structural probes.

Peter Zhifeng Qin , Anna Marie Pyle
Methods 18 ( 1) 60 -70

76
1999
SEQUENCE SPECIFICITY OF A GROUP II INTRON RIBOZYME : MULTIPLE MECHANISMS FOR PROMOTING UNUSUALLY HIGH DISCRIMINATION AGAINST MISMATCHED TARGETS

Qing Xiang , Peter Zhifeng Qin , William J. Michels , Keri Freeland
Biochemistry 37 ( 11) 3839 -3849

48
1998
Reduced Expression of VEGF-A in Human Retinal Pigment Epithelial Cells and Human Muller Cells Following CRISPR-Cas9 Ribonucleoprotein-Mediated Gene Disruption.

Hossein Ameri , Christopher Murat , Amirmohsen Arbabi , Wei Jiang
Translational Vision Science & Technology 9 ( 8) 23 -23

1
2020
Antagonistic substrate binding by a group II intron ribozyme.

Peter Zhifeng Qin , Anna Marie Pyle
Journal of Molecular Biology 291 ( 1) 15 -27

18
1999
The architectural organization and mechanistic function of group II intron structural elements

Peter Zhifeng Qin , Anna Marie Pyle
Current Opinion in Structural Biology 8 ( 3) 301 -308

197
1998
Theory and simulation

Steven J Gamblin , Stephen J Smerdon , Michael J Bailey , Peter Zhifeng Qin

Studying RNA folding by fluorescence spectroscopy

Peter Zhifeng Qin
Columbia University

2
1999
Measuring nanometer distances in nucleic acids using a sequence-independent nitroxide probe.

Peter Z Qin , Ian S Haworth , Qi Cai , Ana K Kusnetzow
Nature Protocols 2 ( 10) 2354 -2365

82
2007
A nucleotide-independent cyclic nitroxide label for monitoring segmental motions in nucleic acids

Phuong H Nguyen , Anna M Popova , Kálmán Hideg , Peter Z Qin
BMC Biophysics 8 ( 1) 6 -6

16
2015
Application of NMR and EPR methods to the study of RNA.

Peter Z Qin , Thorsten Dieckmann
Current Opinion in Structural Biology 14 ( 3) 350 -359

69
2004
Guiding ribozyme cleavage through motif recognition: the mechanism of cleavage site selection by a group II intron ribozyme

Linhui Julie Su , Peter Z Qin , William J Michels , Anna Marie Pyle
Journal of Molecular Biology 306 ( 4) 655 -668

50
2001
DNA mini-circles reveal effects of DNA topology on CRISPR-Cas9 functions

Yukang Liu , Peter Z Qin
Biophysical Journal 122 ( 3) 72a

2023
CRISPR-Cas9 activities with truncated 16-nucleotide RNA guides are tuned by target duplex stability beyond the RNA/DNA hybrid

Yue Li , Brendon H Cooper , Yukang Liu , Difei Wu
Biochemistry 62 ( 17) 2541–2548 -2541–2548

2023
Generation of tamoxifen‐inducible Tfap2b‐CreERT2 mice using CRISPR‐Cas9

Mingyi Zhang , Jifan Feng , Yue Li , Peter Z Qin
genesis 62 ( 1) e23582 -e23582

1
2024
Coordinated actions of Cas9 HNH and RuvC nuclease domains are regulated by the bridge helix and the target DNA sequence

Kesavan Babu , Venkatesan Kathiresan , Pratibha Kumari , Sydney Newsom
Biochemistry 60 ( 49) 3783 -3800

15
2021
Differential Divalent Metal Binding by SpyCas9's RuvC Active Site Contributes to Nonspecific DNA Cleavage

Sydney N Newsom , Duen-Shian Wang , Saadi Rostami , Isabelle Schuster
The CRISPR Journal 6 ( 6) 527 -542

2023