Activation of the S100A7/RAGE Pathway by IGF-1 Contributes to Angiogenesis in Breast Cancer

Rosamaria Lappano , Marcello Maggiolini , Veronica Vella , Livia Manzella
Cancers 13 ( 4) 621

2021
Copper activates HIF-1α/GPER/VEGF signalling in cancer cells

Damiano Cosimo Rigiracciolo , Andrea Scarpelli , Rosamaria Lappano , Assunta Pisano
Oncotarget 6 ( 33) 34158 -34177

66
2015
GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells

Damiano Cosimo Rigiracciolo , Andrea Scarpelli , Rosamaria Lappano , Assunta Pisano
Oncotarget 7 ( 1) 94 -111

41
2016
GPER Mediates Cardiotropic Effects in Spontaneously Hypertensive Rat Hearts

Ernestina Marianna De Francesco , Tommaso Angelone , Teresa Pasqua , Marco Pupo
PLoS ONE 8 ( 8) e69322

34
2013
A mitochondrial based oncology platform for targeting cancer stem cells (CSCs): MITO-ONC-RX.

Federica Sotgia , Bela Ozsvari , Marco Fiorillo , Ernestina Marianna De Francesco
Cell Cycle 17 ( 17) 2091 -2100

26
2018
Microenvironmental Determinants of Breast Cancer Metastasis: Focus on the Crucial Interplay Between Estrogen and Insulin/Insulin-Like Growth Factor Signaling.

Veronica Vella , Ernestina Marianna De Francesco , Rosamaria Lappano , Maria Grazia Muoio
Frontiers in Cell and Developmental Biology 8 608412

1
2020
SLC37A1 Gene expression is up-regulated by epidermal growth factor in breast cancer cells

Domenico Iacopetta , Rosamaria Lappano , Anna Rita Cappello , Marianna Madeo
Breast Cancer Research and Treatment 122 ( 3) 755 -764

23
2010
NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting “stemness”

Gloria Bonuccelli , Ernestina Marianna De Francesco , Rianne de Boer , Herbert B. Tanowitz
Oncotarget 8 ( 13) 20667 -20678

70
2017
Niacin activates the G protein estrogen receptor (GPER)-mediated signalling

Maria Francesca Santolla , Ernestina Marianna De Francesco , Rosamaria Lappano , Camillo Rosano
Cellular Signalling 26 ( 7) 1466 -1475

30
2014
The G protein estrogen receptor (GPER) is regulated by endothelin-1 mediated signaling in cancer cells.

Viviana Bartella , Ernestina Marianna De Francesco , Maria Grazia Perri , Rosita Curcio
Cellular Signalling 28 ( 2) 61 -71

19
2016
Bisphenol A induces gene expression changes and proliferative effects through GPER in breast cancer cells and cancer-associated fibroblasts.

Marco Pupo , Assunta Pisano , Rosamaria Lappano , Maria Francesca Santolla
Environmental Health Perspectives 120 ( 8) 1177 -1182

284
2012
Estriol acts as a GPR30 antagonist in estrogen receptor-negative breast cancer cells.

Rosamaria Lappano , Camillo Rosano , Paola De Marco , Ernestina Marianna De Francesco
Molecular and Cellular Endocrinology 320 ( 1) 162 -170

87
2010
The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes

Rosamaria Lappano , Anna Grazia Recchia , Ernestina Marianna De Francesco , Tommaso Angelone
PLOS ONE 6 ( 1)

74
2011
HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)

Ernestina Marianna De Francesco , Rosamaria Lappano , Maria Francesca Santolla , Stefania Marsico
Breast Cancer Research 15 ( 4) 1 -18

216
2013
GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response

Paola De Marco , Rosamaria Lappano , Ernestina Marianna De Francesco , Francesca Cirillo
Scientific Reports 6 ( 1) 24354 -24354

34
2016
Mitochondrial Fission Factor (MFF) Inhibits Mitochondrial Metabolism and Reduces Breast Cancer Stem Cell (CSC) Activity.

Rosa Sánchez-Alvarez , Ernestina Marianna De Francesco , Marco Fiorillo , Federica Sotgia
Frontiers in Oncology 10 1776 -1776

19
2020
Cross-talk between GPER and growth factor signaling.

Rosamaria Lappano , Paola De Marco , Ernestina Marianna De Francesco , Adele Chimento
The Journal of Steroid Biochemistry and Molecular Biology 137 50 -56

54
2013
Recent Advances on the Role of G Protein-Coupled Receptors in Hypoxia-Mediated Signaling

Rosamaria Lappano , Damiano Rigiracciolo , Paola De Marco , Silvia Avino
Aaps Journal 18 ( 2) 305 -310

16
2016
Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs)

Ernestina Marianna De Francesco , Gloria Bonuccelli , Marcello Maggiolini , Federica Sotgia
Oncotarget 8 ( 40) 67269 -67286

42
2017
GPER Mediates Activation of HIF1α/VEGF Signaling by Estrogens

Ernestina Marianna De Francesco , Michele Pellegrino , Maria Francesca Santolla , Rosamaria Lappano
Cancer Research 74 ( 15) 4053 -4064

72
2014