Catalysis in the Total Synthesis of Bryostatin 16

Aubry K. Miller
Angewandte Chemie 48 ( 18) 3221 -3223

4
2009
Katalyse in der Totalsynthese von Bryostatin 16

Aubry K. Miller
Angewandte Chemie 121 ( 18) 3268 -3271

1
2009
D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma.

Stefan Pusch , Leonille Schweizer , Ann-Christin Beck , Johanna-Marie Lehmler
Acta neuropathologica communications 2 ( 1) 19 -19

54
2014
Development of novel lewis acid catalyzed cycloisomerizations: synthesis of bicyclo[3.1.0]hexenes and cyclopentenones

Aubry K Miller , Matthew R Banghart , Christopher M Beaudry , Judy M Suh
Tetrahedron 59 ( 45) 8919 -8930

33
2003
A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl

Gianna Triller , Evi P Vlachou , Hamidreza Hashemi , Monique van Straaten
Cell reports 42 ( 2)

2023
Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target

Severin Lechner , Martin Ian P Malgapo , Christian Grätz , Raphael R Steimbach
Nature Chemical Biology 18 ( 8) 812 -820

13
2022
Commonly used alkylating agents limit persulfide detection by converting protein persulfides into thioethers

Danny Schilling , Uladzimir Barayeu , Raphael R Steimbach , Deepti Talwar
Angewandte Chemie 134 ( 30) e202203684

5
2022
Bioinspired Asymmetric Total Synthesis of Emeriones A--C

Sven Jänner , Daniel Isak , Yuli Li , Kendall N Houk
Angewandte Chemie 134 ( 32) e202205878

2
2022
Histone deacetylase-10 liberates spermidine to support polyamine homeostasis and tumor cell growth

Tracy Murray Stewart , Jackson R Foley , Cassandra E Holbert , Glynis Klinke
Journal of Biological Chemistry 298 ( 10)

2022
Aza-SAHA derivatives are selective histone deacetylase 10 chemical probes that inhibit polyamine deacetylation and phenocopy HDAC10 knockout

Raphael R Steimbach , Corey J Herbst-Gervasoni , Severin Lechner , Tracy Murray Stewart
Journal of the American Chemical Society 144 ( 41) 18861 -18875

3
2022
Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins

Hana Nůsková , Marina V Serebryakova , Anna Ferrer-Caelles , Timo Sachsenheimer
Nature communications 12 ( 1) 4590

10
2021
A KLK6 activity-based probe reveals a role for KLK6 activity in pancreatic cancer cell invasion

Leran Zhang , Scott Lovell , Elena De Vita , Pravin Kumar Ankush Jagtap
Journal of the American Chemical Society 144 ( 49) 22493 -22504

8
2022
Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid

Severin Lechner , Raphael R Steimbach , Longlong Wang , Marshall L Deline
Nature Communications 14 ( 1) 3548 -3548

7
2023
Decrypting lysine deacetylase inhibitor action and protein modifications by dose-resolved proteomics

Yun-Chien Chang , Christian Gnann , Raphael R Steimbach , Florian P Bayer
Cell Reports 43 ( 6)

2024
Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target (Apr, 10.1038/s41589-022-01015-5, 2022)

Severin Lechner , Martin Ian P Malgapo , Christian Graetz , Raphael R Steimbach
NATURE CHEMICAL BIOLOGY 18 ( 8) 913 -913

2022
First fluorescent acetylspermidine deacetylation assay for HDAC10 identifies selective inhibitors with cellular target engagement

Daniel Herp , Johannes Ridinger , Dina Robaa , Stephen A Shinsky
ChemBioChem 23 ( 14) e202200180 -e202200180

11
2022
Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals

Uladzimir Barayeu , Danny Schilling , Mohammad Eid , Thamara Nishida Xavier da Silva
Nature chemical biology 19 ( 1) 28 -37

105
2023
ORGN 697-Toward a total synthesis of guanacastepene E

Aubry K Miller , Chambers C Hughes , Joshua J Kennedy-Smith , Dirk Trauner
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 232

2006