GENERATION OF LAYERED TRANSCRIPTIONAL CIRCUITRY USING CRISPR SYSTEMS

Yinqing Li , Ron Weiss , Samira Kiani , Jacob S. Beal

1
2016
Cas9 gRNA engineering for genome editing, activation and repression

Samira Kiani , Alejandro Chavez , Marcelle Tuttle , Richard N Hall
PMC

300
2015
A UNIVERSAL PLATFORM TO ENHANCE CRISPR-BASED GENE EDITING FOR IN VIVO THERAPIES

Mohammed R. Ebrahimkhani , Jennifer Chapman , Samira Kiani

2020
Genetically guided engineering of human liver tissue from pluripotent stem cells

Samira Kiani , Jacquelyn Kilbourne , Mohammad Ebrahimkhani , Farzaneh Moghadam
42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence

2019
The NIH Somatic Cell Genome Editing program

Krishanu Saha , Erik J Sontheimer , PJ Brooks , Melinda R Dwinell
Nature 592 ( 7853) 195 -204

61
2021
Multicellular systems to translate somatic cell genome editors to human

Victor Hernandez-Gordillo , Thomas Caleb Casolaro , Mo R. Ebrahimkhani , Samira Kiani
Current Opinion in Biomedical Engineering 16 72 -81

1
2020
Fluorescent Guide RNAs Facilitate Development of Layered Pol II-Driven CRISPR Circuits.

David J. Menn , Swechchha Pradhan , Samira Kiani , Xiao Wang
ACS Synthetic Biology 7 ( 8) 1929 -1936

7
2018
Alteration in male reproductive system in experimental cholestasis: roles for opioids and nitric oxide overproduction.

Samira Kiani , Behzad Valizadeh , Bahram Hormazdi , Hoda Samadi
European Journal of Pharmacology 615 ( 1) 246 -251

21
2009
An enhanced CRISPR repressor for targeted mammalian gene regulation

Nan Cher Yeo , Alejandro Chavez , Alissa Lance-Byrne , Yingleong Chan
Nature Methods 15 ( 8) 611 -616

316
2018
Nitric oxide: a new concept in chronic sinusitis pathogenesis

Mohsen Naraghi , Armin Farajzadeh Deroee , MohammadReza Ebrahimkhani , Samira Kiani
American Journal of Otolaryngology 28 ( 5) 334 -337

37
2007
Genetic engineering of human pluripotent cells using TALE nucleases

Dirk Hockemeyer , Haoyi Wang , Samira Kiani , Christine S Lai
Nature Biotechnology 29 ( 8) 731 -734

1,458
2011
Synthetic immunomodulation with a CRISPR super-repressor in vivo.

Farzaneh Moghadam , Ryan LeGraw , Jeremy J Velazquez , Nan Cher Yeo
Nature Cell Biology 22 ( 9) 1143 -1154

24
2020
Opioid system blockade decreases collagenase activity and improves liver injury in a rat model of cholestasis

Samira Kiani , Mohammad R Ebrahimkhani , Ahmad Shariftabrizi , Behzad Doratotaj
Journal of Gastroenterology and Hepatology 22 ( 3) 406 -413

15
2007
Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes

Shayesteh R Ferdosi , Radwa Ewaisha , Farzaneh Moghadam , Sri Krishna
Nature Communications 10 ( 1) 1842 -1842

113
2019
Opioid receptor blockade improves mesenteric responsiveness in biliary cirrhosis.

Mohammad R. Ebrahimkhani , Leila Moezi , Samira Kiani , Shahin Merat
Digestive Diseases and Sciences 53 ( 11) 3007 -3011

10
2008
Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids

Jeremy J. Velazquez , Ryan LeGraw , Farzaneh Moghadam , Yuqi Tan
Cell systems 12 ( 1)

41
2021
Approaches to Reduce CRISPR Off-Target Effects for Safer Genome Editing:

Jennifer E. Chapman , David Gillum , Samira Kiani
Applied Biosafety 22 ( 1) 7 -13

13
2017
The 2017 Arizona Biosecurity Workshop: An Open Dialogue About Biosecurity

David Gillum , Luis Alberto Ochoa Carrera , Irene Alvarez Mendoza , Phillip Bates
Applied Biosafety 23 ( 4) 233 -241

1
2018
Synthetic Maturation of Multilineage Human Liver Organoids via Genetically Guided Engineering

Jeremy J. Velazquez , Ryan LeGraw , Farzaneh Moghadam , Yuqi Tan
bioRxiv

3
2020
Engineered CRISPR Systems for Next Generation Gene Therapies

Michael Pineda , Farzaneh Moghadam , Mo R. Ebrahimkhani , Samira Kiani
ACS Synthetic Biology 6 ( 9) 1614 -1626

18
2017