Chunwan Lu, Ph.D.
机构: Associate Professor, School of Life Sciences, Tianjin University
主页: tju.edu.cn
每年引用次数
引用次数
引用: 2,696
H-指数: 28
I10-指数 : 41
出版物: 75
Abstract A32: The SUV39H1-H3K9me3 pathway represses cytotoxic T lymphocyte effector expression to confer colon carcinoma immune escape
Iryna O. Lebedyeva , Samuel Kulp , Aaron H. Colby , Cedric Pearce
Cancer immunology research 8
2020
Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis.
David Ostrov , Nicolas Coant , Aaron H. Colby , Chunwan Lu
Journal of Immunology 206 ( 6) 1395 -1404
27
2021
Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression.
Chunwan Lu , Dafeng Yang , Dafeng Yang , Kebin Liu
Cancers 13 ( 5) 1006
18
2021
DDRGK1, a crucial player of ufmylation system, is indispensable for autophagic degradation by regulating lysosomal function
Chunwan Lu , Ming Shen , Honglin Li , Honglin Liu
Cell Death and Disease 12 ( 5) 416 -416
10
2021
SUV39H1 Represses the Expression of Cytotoxic T-Lymphocyte Effector Genes to Promote Colon Tumor Immune Evasion.
Chunwan Lu , Dafeng Yang , John D. Klement , Il Kyu Oh
Cancer immunology research 7 ( 3) 414 -427
14
2019
Inhibition of gastric tumor growth by a novel Hsp90 inhibitor
Chunwan Lu , Di Liu , Jing Jin , Hemantkumar Deokar
Biochemical Pharmacology 85 ( 9) 1246 -1256
22
2013
The NF-κB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription.
Priscilla S. Simon , Sarah K. Sharman , Chunwan Lu , Dafeng Yang
BMC Cancer 15 ( 1) 770 -770
33
2015
Loss of Fas Expression and Function Is Coupled with Colon Cancer Resistance to Immune Checkpoint Inhibitor Immunotherapy
Wei Xiao , Mohammed L. Ibrahim , Priscilla S. Redd , John D. Klement
Molecular Cancer Research 17 ( 2) 420 -430
8
2019
Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes.
Genevieve L. Coe , Priscilla S. Redd , Amy V. Paschall , Chunwan Lu
Scientific Reports 6 ( 1) 30816 -30816
12
2016
CD133+CD24lo defines a 5-Fluorouracil-resistant colon cancer stem cell-like phenotype.
Amy V. Paschall , Dafeng Yang , Chunwan Lu , Priscilla S. Redd
Oncotarget 7 ( 48) 78698 -78712
16
2016
Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells.
Feiyan Liu , Xia Li , Chunwan Lu , Aiping Bai
Oncotarget 7 ( 51) 83907 -83925
40
2016
Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death
Tsadik Habtetsion , Zhi-Chun Ding , Wenhu Pi , Tao Li
Cell Metabolism 28 ( 2)
17
2018
MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment
T. William Mudd , Chunwan Lu , John D. Klement , Kebin Liu
Cellular Immunology 360 104260
15
2021
IFNAR1 Controls Autocrine Type I IFN Regulation of PD-L1 Expression in Myeloid-Derived Suppressor Cells.
Wei Xiao , John D. Klement , Chunwan Lu , Mohammed L. Ibrahim
Journal of Immunology 201 ( 1) 264 -277
61
2018
Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells
Chunwan Lu , Dafeng Yang , Maria E. Sabbatini , Aaron H. Colby
BMC Cancer 18 ( 1) 1 -12
42
2018
Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes
Chunwan Lu , John D. Klement , Mohammed L. Ibrahim , Wei Xiao
Journal for ImmunoTherapy of Cancer 7 ( 1) 157
26
2019
SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth
Chunwan Lu , John D. Klement , Dafeng Yang , Thomas Albers
Cancer Letters 476 87 -96
2
2020
The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells
Chunwan Lu , Priscilla S. Redd , Jeffrey R. Lee , Natasha Savage
OncoImmunology 5 ( 12)
91
2016
JAK-STAT-mediated chronic inflammation impairs cytotoxic T lymphocyte activation to decrease anti-PD-1 immunotherapy efficacy in pancreatic cancer
Chunwan Lu , Asif Talukder , Natasha M. Savage , Nagendra Singh
OncoImmunology 6 ( 3)
67
2017
H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells
Priscilla S. Redd , Chunwan Lu , John D. Klement , Mohammed L. Ibrahim
OncoImmunology 7 ( 9)
8
2018