Gabriel Helmlinger
机构: Vice-President, Biorchestra
每年引用次数
引用次数
引用: 6,225
H-指数: 24
I10-指数 : 38
出版物: 130
Fluorescence ratio imaging of interstitial pH in solid tumours: effect of glucose on spatial and temporal gradients.
M Dellian , G Helmlinger , F Yuan , RK Jain
British Journal of Cancer 74 ( 8) 1206 -1215
73
1996
Pharmacometric Modeling of Naloxegol Efficacy and Safety: Impact on Dose and Label
N Al-Huniti , D Zhou , H Xu , S Aksenov
Clinical Pharmacology & Therapeutics 102 ( 5) 741 -744
8
2017
Quantitative Systems Pharmacology Modeling of Drug-Induced Proximal Tubular (Pt) Injury
Y Gebremichael , J Lu , H Shankaran , J Mettetal
CLINICAL PHARMACOLOGY & THERAPEUTICS 101 ( S 1) S64 -S64
2
2017
CONTRIBUTION AND REGULATION OF SGLT1 AND SGLT2 IN HEALTHY AND TYPE 2 DIABETES SUBJECTS: A DRUG-DISEASE MODELING STUDY.
T Yakovleva , V Sokolov , L Chu , RC Penland
CLINICAL PHARMACOLOGY & THERAPEUTICS 103 S51 -S51
1
2018
USING A SYSTEMS PHARMACOLOGY MODEL TO INVESTIGATE POTASSIUM HOMEOSTASIS IN HEALTHY AND HYPERKALEMIC SUBJECTS.
G Helmlinger , L Chu , S Aksenov , R Penland
CLINICAL PHARMACOLOGY & THERAPEUTICS 107 S115 -S115
2020
DIFFERENTIAL INHIBITION OF SGLT1 BY CANAGLIFLOZIN VS. DAPAGLIFLOZIN AND EMPAGLIFLOZIN: A DRUG-DISEASE MODELING STUDY.
T Yakovleva , V Sokolov , L Chu , RC Penland
CLINICAL PHARMACOLOGY & THERAPEUTICS 103 S57 -S57
2018
DYNAMIC PREDICTION OF PROGRESSION FREE SURVIVAL (PFS) AND OVERALL SURVIVAL (OS) IN NON-SMALL CELL LUNG CANCER (NSCLC) USING TUMOR SIZE: A LONGITUDINAL JOINT MODELING APPROACH.
N Al-Huniti , D Onishchenko , H Xu , D Zhou
CLINICAL PHARMACOLOGY & THERAPEUTICS 101 ( S 1) S55 -S55
2
2017
PERFORMANCEOF SEQUENTIAL AND SIMULTANEOUS PK/PD MODELING OF QT INTERVALS WITH PHASE I STUDIES TO PREDICT THOROUGH QT STUDY OUTCOMES.
J Lu , N Al-Huniti , G Helmlinger , J Li
CLINICAL PHARMACOLOGY & THERAPEUTICS 103 S18 -S19
2018
EXPOSURE-QT PROLONGATION ASSESSMENT USING LINEAR MIXED-EFFECTS VS. LINEAR QUANTILE MIXED-EFFECTS MODELING OF PHASE I STUDY DATA.
J Lu , N Al-Huniti , E Masson , G Helmlinger
CLINICAL PHARMACOLOGY & THERAPEUTICS 103 S19 -S19
2018
DIFFERENTIATION OF ANTI-PCSK9 ANTIBODIES AND SYNTHESIS INHIBITORS: A DRUG-DISEASE MODELING STUDY.
V Sokolov , E Hurt-Camejo , C Nilsson , K Zhudenkov
CLINICAL PHARMACOLOGY & THERAPEUTICS 103 S57 -S57
2018
The intracelluar calcium response of single endothelial cells subjected to fluid-imposed steady and pulsatile shear stress.
G Helmlinger
Biofluid Mechanics. 509 -521
3
1994
SGLT2 inhibition differentially reduces extracellular fluid volume relative to blood volume: a hypothesis for heart failure protection
K Melissa Hallow , G Helmlinger , PJ Greasley , DW Boulton
European Journal of Heart Failure 19 345 -345
2
2017
EFFECT OF DRUG-INDUCED ELECTROLYTE-FREE WATER CLEARANCE ON SODIUM HOMEOSTASIS AND PLASMA AND INTERSTITIAL FLUID VOLUMES: A MODELING ANALYSIS
M Rahman , D Boulton , G Helmlinger , P Greasley
CLINICAL PHARMACOLOGY & THERAPEUTICS 105 S109 -S109
2019
Biology by Flow
RM Nerem , PR Girard , G Helmlinger , O Thoumine
Cell Mechanics and Cellular Engineering 55 -55
2012
Similar-Yet different: IGF and EGF signaling in comparison.
BM Schoeberl , K West , E Pace , A Kudla
CLINICAL CANCER RESEARCH 11 ( 24) 9044S -9044S
2005
Inhibition of tumor growth by solid stress
G HELMLINGER , P NETTI , H LICHTENBELD , R MELDER
Biorheology 32 345 -346
1995
Preclinical cardiac safety assessment of pharmaceutical compounds using an integrated systems-based computer model of the heart.
D BOTTINO , R PENLAND , A STAMPS , M TRAEBERT
Progress in Biophysics & Molecular Biology 90 ( 1) 414 -443
55
2006
THE REGULATION OF VASCULAR ENDOTHELIAL BIOLOGY BY FLOW
G HELMLINGER , O THOUMINE , TF WIESNER , RM NEREM
JOURNAL OF CELLULAR BIOCHEMISTRY 242 -242
1994
EFFECTS OF PULSATILE FLOW ON THE MORPHOLOGY OF BOVINE AORTIC ENDOTHELIAL-CELLS
G HELMLINGER , RM NEREM
FASEB JOURNAL 5 ( 4) A527 -A527
1991
Exenatide effects on gastric emptying and oral glucose appearance in plasma: A quantitative assessment using an integrative systems pharmacology model
Veronika Voronova , Kirill Zhudenkov , Robert C Penland2a , David W Boulton2b
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 45 S112 -S113
2018