Sebastiano Pasqualato
机构: Senior Manager Biophysics, National Facility for Structural Biology, Human Technopole
每年引用次数
引用次数
引用: 4,285
H-指数: 27
I10-指数 : 34
出版物: 54
Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions.
Sebastiano Pasqualato , Vincent Olieric , Silvia Monzani , Valentina Cecatiello
Nature Communications 12 ( 1) 2070 -2070
2021
Inhibiting LSD1 suppresses coronavirus-induced inflammation but spares innate antiviral activity
Ilaria Schiavoni , Sebastiano Pasqualato , Gabriele Buttinelli , Isabella Pallavicini
bioRxiv
2021
Structure of Arf6-GDP suggests a basis for guanine nucleotide exchange factors specificity.
Jacqueline Cherfils , Julie Ménétrey , Eric Macia , Sebastiano Pasqualato
Nature Structural & Molecular Biology 7 ( 6) 466 -469
76
2000
Mechanism of domain closure of Sec7 domains and role in BFA sensitivity.
Louis Renault , Petya Christova , Bernard Guibert , Sebastiano Pasqualato
Biochemistry 41 ( 11) 3605 -3612
33
2002
Epistasis, aneuploidy, and gain-of-function mutations underlie the evolution of resistance to induced microtubule depolymerization
Mattia Pavani , Paolo Bonaiuti , Elena Chiroli , Fridolin Gross
bioRxiv
2020
Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models
Alessia Romussi , Anna Cappa , Paola Vianello , Silvia Brambillasca
ACS Medicinal Chemistry Letters 11 ( 5) 754 -759
5
2020
The Ndc80 kinetochore complex forms oligomeric arrays along microtubules
Gregory M. Alushin , Vincent H. Ramey , Sebastiano Pasqualato , David A. Ball
Nature 467 ( 7317) 805 -810
225
2010
Persistence of Anti-SARS-CoV-2 Antibodies in Non-Hospitalized COVID-19 Convalescent Health Care Workers
Margherita Bruni , Valentina Cecatiello , Angelica Diaz-Basabe , Georgia Lattanzi
Journal of Clinical Medicine 9 ( 10) 3188
72
2020
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure–Activity Relationship
Paola Vianello , Luca Sartori , Federica Amigoni , Anna Cappa
Journal of Medicinal Chemistry 60 ( 5) 1693 -1715
37
2017
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.
Luca Sartori , Ciro Mercurio , Federica Amigoni , Anna Cappa
Journal of Medicinal Chemistry 60 ( 5) 1673 -1692
41
2017
Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex
Claudio Ciferri , Sebastiano Pasqualato , Emanuela Screpanti , Gianluca Varetti
Cell 133 ( 3) 427 -439
417
2008
Structure of a Ubiquitin-Loaded Hect Ligase Reveals the Molecular Basis for Catalytic Priming
Elena Maspero , Eleonora Valentini , Sara Mari , Valentina Cecatiello
Nature Structural & Molecular Biology 20 ( 6) 696 -701
107
2013
The Structural GDP/GTP Cycle of Rab11 Reveals a Novel Interface Involved in the Dynamics of Recycling Endosomes
Sebastiano Pasqualato , Francesca Senic-Matuglia , Louis Renault , Bruno Goud
Journal of Biological Chemistry 279 ( 12) 11480 -11488
70
2004
Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin.
Valentina Nardone , Antonio Chaves-Sanjuan , Michela Lapi , Cristina Airoldi
Cells 9 ( 11) 2370
1
2020
Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front–back' communication
Sebastiano Pasqualato , Louis Renault , Jacqueline Cherfils
EMBO Reports 3 ( 11) 1035 -1041
271
2002
Crystallographic Evidence for Substrate-Assisted GTP Hydrolysis by a Small GTP Binding Protein
Sebastiano Pasqualato , Jacqueline Cherfils
Structure 13 ( 4) 533 -540
43
2005
Structural and functional framework for the autoinhibition of nedd4-family ubiquitin ligases
Sara Mari , Natalia Ruetalo , Elena Maspero , Mira C. Stoffregen
Structure 22 ( 11) 1639 -1649
50
2014
Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization
Arsen Petrovic , Shyamal Mosalaganti , Jenny Keller , Marta Mattiuzzo
Molecular Cell 53 ( 4) 591 -605
85
2014
The Ndc80 Loop Region Facilitates Formation of Kinetochore Attachment to the Dynamic Microtubule Plus End
Jean-François Maure , Shinya Komoto , Yusuke Oku , Akihisa Mino
Current Biology 21 ( 3) 207 -213
87
2011
Organizational Principles of the NuMA-Dynein Interaction Interface and Implications for Mitotic Spindle Functions.
Cristina Renna , Francesca Rizzelli , Manuel Carminati , Chiara Gaddoni
Structure 28 ( 7)
2
2020