引用次数
引用: 10,345
H-指数: 33
I10-指数 : 39
出版物: 57
Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites.
Yevgeniya Antonova-Koch , Elizabeth A. Winzeler , David A. Fidock , Kathryn J. Wicht
Scientific Reports 11 ( 1) 2121 -2121
1
2021
Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone
Tina S Skinner-Adams , Gillian M Fisher , Andrew G Riches , Oliver E Hutt
Communications Biology 2 ( 1) 166 -166
7
2019
Selective and Specific Inhibition of the Plasmodium falciparum Lysyl-tRNA Synthetase by the Fungal Secondary Metabolite Cladosporin
David M. Plouffe , Stephan Meister , Sven Schuierer , Uwe Plikat
Cell Host & Microbe 11 ( 6) 654 -663
148
2012
High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission
David M. Plouffe , Melanie Wree , Alan Y. Du , Stephan Meister
Cell Host & Microbe 19 ( 1) 114 -126
81
2016
Immunity-Related Genes and Gene Families in Anopheles gambiae
George K Christophides , Evgeny Zdobnov , Carolina Barillas-Mury , Ewan Birney
Science 298 ( 5591) 159 -165
1,088
2002
The Genome Sequence of the Malaria Mosquito Anopheles gambiae
Robert A Holt , G Mani Subramanian , Aaron Halpern , Granger G Sutton
Science 298 ( 5591) 129 -149
2,518
2002
Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages.
Finn K. Hansen , Subathdrage D.M. Sumanadasa , Katharina Stenzel , Sandra Duffy
European Journal of Medicinal Chemistry 82 204 -213
56
2014
A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure–Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines
C le Manach , T Paquet , C Brunschwig , M Njoroge
Journal of Medicinal Chemistry 58 ( 21) 8713 -8722
16
2015
Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials
Neil R. Norcross , Beatriz Baragaña , Caroline Wilson , Irene Hallyburton
Journal of Medicinal Chemistry 59 ( 13) 6101 -6120
7
2016
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy.
Beatriz Baragaña , Neil R. Norcross , Caroline Wilson , Achim Porzelle
Journal of Medicinal Chemistry 59 ( 21) 9672 -9685
36
2016
Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle.
Claire Le Manach , Aloysius T. Nchinda , Tanya Paquet , Diego Gonzàlez Cabrera
Journal of Medicinal Chemistry 59 ( 21) 9890 -9905
32
2016
3-Hydroxy-N′-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally
Michael Leven , Tanja C. Knaab , Jana Held , Sandra Duffy
Journal of Medicinal Chemistry 60 ( 14) 6036 -6044
3
2017
The Activities of Current Antimalarial Drugs on the Life Cycle Stages of Plasmodium: A Comparative Study with Human and Rodent Parasites
Michael Delves , David Plouffe , Christian Scheurer , Stephan Meister
PLoS Medicine 9 ( 2) e1001169
266
2012
Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL), a Resistance Mechanism for Two Distinct Compound Classes.
Pamela A. Magistrado , Victoria C. Corey , Amanda K. Lukens , Greg LaMonte
ACS Infectious Diseases 2 ( 11) 816 -826
21
2016
Developing Plasmodium vivax Resources for Liver Stage Study in the Peruvian Amazon Region.
Pamela Orjuela-Sanchez , Zaira Hellen Villa , Marta Moreno , Carlos Tong-Rios
ACS Infectious Diseases 4 ( 4) 531 -540
5
2018
The Plasmodium eukaryotic initiation factor-2α kinase IK2 controls the latency of sporozoites in the mosquito salivary glands
Min Zhang , Clare Fennell , Lisa Ranford-Cartwright , Ramanavelan Sakthivel
Journal of Experimental Medicine 207 ( 7) 1465 -1474
106
2010
Design and Synthesis of Terephthalic Acid‐Based Histone Deacetylase Inhibitors with Dual‐Stage Anti‐Plasmodium Activity
Katharina Stenzel , Ming Jang Chua , Sandra Duffy , Yevgeniya Antonova-Koch
ChemMedChem 12 ( 19) 1627 -1636
6
2017
8-Aminoquinolines with an Aminoxyalkyl Side Chain Exert in vitro Dual-Stage Antiplasmodial Activity.
Michael Leven , Jana Held , Sandra Duffy , Leandro A. Alves Avelar
ChemMedChem 14 ( 4) 501 -511
2
2019
Substituted Aminoacetamides as Novel Leads for Malaria Treatment
Neil R. Norcross , Caroline Wilson , Beatriz Baragaña , Irene Hallyburton
ChemMedChem 14 ( 14) 1329 -1335
2
2019
Design and synthesis of high affinity inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferases directed by ligand efficiency dependent lipophilicity (LELP).
Mark D. Rackham , James A. Brannigan , Kaveri Rangachari , Stephan Meister
Journal of Medicinal Chemistry 57 ( 6) 2773 -2788
43
2014
Elizabeth A. Winzeler George Christophides Case W. McNamara George Dimopoulos Carolina Barillas-Mury Joseph Vinetz Kevin P. White Vicky Avery S. Duffy Katherine Andrews Hubert Amrein Rafael Cantera Angela Relógio Benjamin Mordmüller Prof. Sanjeev Kumar David S Roos Lisa Ranford-Cartwright William J Sullivan Jr Christian Doerig John Clayton