Novel multi-targeted agents for Alzheimer's disease: Synthesis, biological evaluation, and molecular modeling of novel 2-[4-(4-substitutedpiperazin-1-yl)phenyl]benzimidazoles
Keriman Ozadali-Sari , Tuba Tüylü Küçükkılınç , Beyza Ayazgok , Ayla Balkan
Bioorganic Chemistry 72 208 -214
17
2017
Novel 3-phenylcoumarin-lipoic acid conjugates as multi-functional agents for potential treatment of Alzheimer's disease.
Leili Jalili-Baleh , Hamid Nadri , Hamid Forootanfar , Alireza Samzadeh-Kermani
Bioorganic Chemistry 79 223 -234
17
2018
Synthesis and biological evaluation of new N-benzylpyridinium-based benzoheterocycles as potential anti-Alzheimer's agents.
Naeimeh Salehi , Bi Bi Fatemeh Mirjalili , Hamid Nadri , Zahra Abdolahi
Bioorganic Chemistry 83 559 -568
27
2019
3-Aryl Coumarin Derivatives Bearing Aminoalkoxy Moiety as Multi-Target-Directed Ligands against Alzheimer's Disease.
Helia Abdshahzadeh , Mostafa Golshani , Hamid Nadri , Iraj Saberi Kia
Chemistry & Biodiversity 16 ( 5)
2019
Design and Synthesis of 2-Substitutedphenyl Benzo[D]Thiazole Derivatives and Their β-Amyloid Aggregation and Cholinesterase Inhibitory Activities
Merve Zengin , Oya Unsal-Tan , Tuba Tüylü Küçükkılınç , Beyza Ayazgok
Pharmaceutical Chemistry Journal 53 ( 4) 322 -328
1
2019
Design, synthesis and evaluation of novel multi-target-directed ligands for treatment of Alzheimer's disease based on coumarin and lipoic acid scaffolds.
Leili Jalili-Baleh , Hamid Forootanfar , Tuba Tüylü Küçükkılınç , Hamid Nadri
European Journal of Medicinal Chemistry 152 600 -614
30
2018
Novel 2-Arylbenzimidazole derivatives as multi-targeting agents to treat Alzheimer’s disease
Oya Unsal-Tan , Keriman Ozadali-Sari , Beyza Ayazgok , Tuba Tüylü Küçükkılınç
Medicinal Chemistry Research 26 ( 7) 1506 -1515
4
2017
Synthesis and neuroprotective activity of novel 1,2,4-triazine derivatives with ethyl acetate moiety against H 2 O 2 and Aβ-induced neurotoxicity
Tuba Tuylu Kucukkilinc , Kamaledin Safari Yanghagh , Beyza Ayazgok , Mohammad Ali Roknipour
Medicinal Chemistry Research 26 ( 11) 3057 -3071
7
2017
The basolateral amygdala-anterior cingulate pathway contributes to depression-like behaviors and comorbidity with chronic pain behaviors in male mice
Léa J Becker , Clémentine Fillinger , Robin Waegaert , Sarah H Journée
Nature Communications 14 ( 1) 2198 -2198
21
2023
The basolateral amygdala-anterior cingulate pathway contributes to depression and its comorbidity with chronic pain
Léa J Becker , Clémentine Fillinger , Robin Waegaert , Pierre Hener
bioRxiv 2022.08. 09.503276 -2022.08. 09.503276
2022
Novel 2-pyrazoline derivatives bearing thiazole ring as dual monoamine oxidase-B and acetylcholinesterase inhibitors also inhibit beta-amyloid fibril
BEYZA Ayazgök , Umut Gökşen , ZEKİYE Tüylü Küçükkılınç , NESRİN Gökhan Kelekçi
2013
Novel benzimidazole derivatives with multi functions on cholinesterase enzymes and neuroprotection
BEYZA Ayazgök , ZEKİYE Tüylü Küçükkılınç , KERİMAN Özadalı Sarı , OYA Ünsal Tan
142
2017
Apoptotic and Necrotic Effects of Low Dose Bisphenol A in SH-SY5Y neuroblastoma cells
BEYZA Ayazgök , ZEKİYE Tüylü Küçükkılınç
2016
big effects of low dose Bisphenol A
BEYZA Ayazgök , ZEKİYE Tüylü Küçükkılınç
Fabad Journal of Pharmaceutical Sciences 42 ( 2)
1
2017
Necroptotic effects of Bisphenol A on SHSY-5Y neuroblastoma cells
BEYZA Ayazgök , ZEKİYE Tüylü Küçükkılınç
Hacettepe Üniversitesi Eczacılık Fakültesinin Akreditasyon Süreci ve Bu Sürecin Kazanımları
BEYZA Ayazgök
Low Dose Bisphenol A Alters Acetylcholinesterase and Butyrylcholinesterase Gene Expression levels
BEYZA Ayazgök , ZEKİYE Tüylü Küçükkılınç
The Studies on Novel Benzimidazole Derivatives as Potential Multifunctional Agents for the Treatment of Alzheimer's Disease
BEYZA Ayazgök , ZEKİYE Tüylü Küçükkılınç
Inhibition of butyrylcholınesterase and acetycholinesterase by Bisphenol A
BEYZA Ayazgök , ZEKİYE TÜYLÜ KÜÇÜKKILINÇ
Effects of Bisphenol A bpa on shsy5y cells evaluatıon of nitric oxide related pathways
BEYZA Ayazgök , ZEKİYE TÜYLÜ KÜÇÜKKILINÇ