Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine

Chang Xie 谢畅 , Zhang-Sen Zhou 周章森 , Na Li 李钠 , Yan Bian 卞艳
Journal of Lipid Research 53 ( 10) 2092 -2101

39
2012
Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome

Chang Xie , Ya-Ping Zhang , Lu Song , Jie Luo
Cell Research 26 ( 10) 1099 -1111

52
2016
Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance.

Xue-Min Gong , Yun-Feng Li , Jie Luo , Ji-Qiu Wang
Nature Metabolism 1 ( 5) 570 -583

8
2019
Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins

Jian Xiao , Jie Luo , Ao Hu , Ting Xiao
Science China Life Sciences 62 ( 9) 1117 -1135

53
2019
Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface.

Bei-Bei Chu , Liang Ge , Chang Xie , Yang Zhao
Journal of Biological Chemistry 284 ( 33) 22481 -22490

48
2009
Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts

Bei-Bei Chu , Ya-Cheng Liao , Wei Qi , Chang Xie
Cell 161 ( 2) 291 -306

318
2015
AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease

Chang Xie , Xue-Min Gong , Jie Luo , Bo-Liang Li
Journal of Lipid Research 58 ( 3) 512 -518

22
2017
Ciliary signaling-patterned smooth muscle drives tubular elongation

Ying Yang , Pekka Paivinen , Chang Xie , Alexis Leigh Krup
bioRxiv

2020
p.N1380del mutation in the pore-forming region of SCN5A gene is associated with cardiac conduction disturbance and ventricular tachycardia

Zhen Yang , Danbo Lu , Lei Zhang , Jialu Hu
Acta Biochimica et Biophysica Sinica 49 ( 3) 270 -276

3
2017
Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity

Chang Xie , Shaun R Abrams , Vicente Herranz-Perez , Jose Manuel García-Verdugo
Developmental Cell 56 ( 24) 3334 -3348

2
2021
Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation

Ying Yang , Pekka Paivinen , Chang Xie , Alexis Leigh Krup
Nature communications 12 ( 1) 7186 -7186

12
2021
Bile acids-mediated intracellular cholesterol transport promotes intestinal cholesterol absorption and NPC1L1 recycling

Jian Xiao , Le-Wei Dong , Shuai Liu , Fan-Hua Meng
Nature Communications 14 ( 1) 6469 -6469

4
2023