Ake Tzu-Hui Lu
机构: Senior Scientist, Computational, San Diego Institute of Science, Altos Labs
每年引用次数
引用次数
引用: 13,522
H-指数: 46
I10-指数 : 83
出版物: 130
Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata.
Stacey L Eggert , Karen L Huyck , Priya Somasundaram , Raghava Kavalla
American Journal of Human Genetics 91 ( 4) 621 -628
55
2012
Dna methylation based biomarkers for life expectancy and morbidity
Stefan Horvath , Ake Tzu-hui Lu
2020
Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons
Dylan A Reid , Patrick J Reed , Johannes CM Schlachetzki , Ioana I Nitulescu
Science 372 ( 6537) 91 -94
1
2021
Multi-species and multi-tissue methylation clocks for age estimation in toothed whales and dolphins.
Martin Haulena , Karen J Steinman , June Mergl , Todd Schmitt
Communications biology 4 ( 1) 642
23
2021
Clonal hematopoiesis associated with epigenetic aging and clinical outcomes.
Daniel Nachun , Ake T Lu , Alexander G Bick , Pradeep Natarajan
Aging Cell
37
2021
Identifying rare-variant associations in parent-child trios using a Gaussian support vector machine.
Ake T Lu , Rita M Cantor
BMC Proceedings 8 ( 1) 1 -4
6
2014
EPIGENETIC CLOCKS OF COMPUTED TOMOGRAPHY MEASURES OF FATTY ORGANS
Ake T Lu , Steve Horvath
Innovation in Aging 3
2019
EPIGENETIC PREDICTORS OF LIFESPAN AND HEALTHSPAN
Ake T Lu , Steve Horvath
Innovation in Aging 3
2019
A mammalian methylation array for profiling methylation levels at conserved sequences
Adriana Arneson , Amin Haghani , Michael J Thompson , Matteo Pellegrini
bioRxiv
71
2021
GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality.
Cathal McCrory , Giovanni Fiorito , Belinda Hernandez , Silvia Polidoro
Journals of Gerontology Series A-biological Sciences and Medical Sciences 76 ( 5) 741 -749
123
2021
Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning
Morgan E Levine , Ake T Lu , David A Bennett , Steve Horvath
Aging (Albany NY) 7 ( 12) 1198 -1211
365
2015
DNA methylation clocks for dogs and humans
Steve Horvath , Ake T Lu , Amin Haghani , Joseph A Zoller
Proceedings of the National Academy of Sciences 119 ( 21) e2120887119
4
2022
Causal epigenetic age uncouples damage and adaptation
Kejun Ying , Hanna Liu , Andrei E Tarkhov , Ake T Lu
bioRxiv 2022 -10
1
2022
Divergent age-related methylation patterns in long and short-lived mammals
Amin Haghani , Nan Wang , Ake T Lu , Khyobeni Mozhui
BioRxiv 2022 -01
3
2022
Epigenetic age and the risk of incident atrial fibrillation
Jason D Roberts , Eric Vittinghoff , Ake T Lu , Alvaro Alonso
Circulation 144 ( 24) 1899 -1911
10
2021
Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study
Fernanda Morales Berstein , Daniel L McCartney , Ake T Lu , Konstantinos K Tsilidis
Elife 11 e75374
6
2022
Meta-analyses identify DNA methylation associated with kidney function and damage
Pascal Schlosser , Adrienne Tin , Pamela R Matias-Garcia , Chris HL Thio
Nature communications 12 ( 1) 7174
12
2021
Genetic loci and metabolic states associated with murine epigenetic aging
Khyobeni Mozhui , Ake T Lu , Caesar Z Li , Amin Haghani
Elife 11 e75244
8
2022
Significant variation in the performance of DNA methylation predictors across data preprocessing and normalization strategies
Anil PS Ori , Ake T Lu , Steve Horvath , Roel A Ophoff
Genome Biology 23 ( 1) 225
1
2022
A systematic evaluation of 41 DNA methylation predictors across 101 data preprocessing and normalization strategies highlights considerable variation in algorithm performance
Anil PS Ori , Ake T Lu , Steve Horvath , Roel A Ophoff
bioRxiv 2021 -09
4
2021