Click Chemistry as a High‐Throughput Amenable Platform in Catalomics

Karunakaran Anandamma Kalesh , Peng-Yu Yang , Rajavel Srinivasan , Shao Qin Yao
Qsar & Combinatorial Science 26 1135 -1144

30
2007
Synthesis of 2,3,5-trisubstituted furans from α-formylaroylketene dithioacetals

K.A. Sasikala , K.A. Kalesh , E.R. Anabha , P. Madhavan Pillai
Tetrahedron Letters 52 ( 14) 1667 -1669

15
2011
Quantitative Proteomics Reveals that Hsp90 Inhibition Dynamically Regulates Global Protein Synthesis in Leishmania mexicana.

Karunakaran Kalesh , Paul W. Denny , Sandeep Sundriyal , Steven L. Cobb
mSystems 6 ( 3)

6
2021
Detectives and helpers: Natural products as resources for chemical probes and compound libraries.

Anutthaman Parthasarathy , Pavan K. Mantravadi , Karunakaran Kalesh
Pharmacology & Therapeutics 216 107688 -107688

7
2020
An Integrated Chemical Proteomics Approach for Quantitative Profiling of Intracellular ADP-Ribosylation

Karunakaran Kalesh , Saulius Lukauskas , Aaron J. Borg , Ambrosius P. Snijders
Scientific Reports 9 ( 1) 6655 -6655

10
2019
Defeating the trypanosomatid trio: proteomics of the protozoan parasites causing neglected tropical diseases

Anutthaman Parthasarathy , Karunakaran Kalesh
RSC medicinal chemistry, 2020, Vol.11(6), pp.625-645 [Peer Reviewed Journal] 11 ( 6) 625 -645

4
2020
The quest for novel antimicrobial compounds : emerging trends in research, development, and technologies.

Pavan Mantravadi , Karunakaran Kalesh , Renwick Dobson , André Hudson
The Journal of Antibiotics 8 ( 1) 8

27
2019
Transcriptome-wide identification of coding and noncoding RNA-binding proteins defines the comprehensive RNA interactome of Leishmania mexicana

Karunakaran Kalesh , Wenbin Wei , Brian S Mantilla , Theodoros I Roumeliotis
Microbiology spectrum 10 ( 1) e02422 -21

2
2022
Inhibition of HSP90 distinctively modulates the global phosphoproteome of Leishmania mexicana developmental stages

Exequiel O Porta , Liqian Gao , Paul W Denny , Patrick G Steel
Microbiology spectrum 11 ( 6) e02960 -23

1
2023
Navigating drug repurposing for Chagas disease: advances, challenges, and opportunities

Exequiel OJ Porta , Karunakaran Kalesh , Patrick G Steel
Frontiers in Pharmacology 14 1233253 -1233253

12
2023
Discovery of Leishmania druggable serine proteases by activity-based protein profiling

Exequiel OJ Porta , Jaime A Isern , Karunakaran Kalesh , Patrick G Steel
Frontiers in Pharmacology 13 929493 -929493

6
2022
6
2020
How can proteomics overhaul our understanding of Leishmania biology?

Paul W Denny , Karunakaran Kalesh
Expert Review of Proteomics 17 ( 11-12) 789 -792

5
2021
Antileishmanial drug development: A review of modern molecular chemical tools and research strategies

Pavan K Mantravadi , Anutthaman Parthasarathy , Karunakaran Kalesh
Current Medicinal Chemistry 28 ( 31) 6337 -6357

2
2021
Microplate-Based Enzymatic Activity Assay Protocol Powered by Activity-Based Probes

Exequiel Porta , Karunakaran Kalesh , Jaime Isern , Patrick Steel

2024
The evolution in pharmacology of infectious diseases: 2022

Exequiel OJ Porta , Ali Saffaei , Karunakaran Kalesh
Frontiers in Pharmacology 15 1386077 -1386077

2024
Recent Advances in Synthesis and Identification of Cyclic Peptides for Bioapplications

Yong Siang Ong , Liqian Gao , Karunakaran A. Kalesh , Zhiqiang Yu
Current Topics in Medicinal Chemistry 17 ( 20) 2302 -2318

17
2017
High-Throughput Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (MptpB) Inhibitors Using Click Chemistry

Lay Pheng Tan , Hao Wu , Peng-Yu Yang , Karunakaran A. Kalesh
Organic Letters 11 ( 22) 5102 -5105

55
2009
Key cell signaling pathways modulated by zerumbone: Role in the prevention and treatment of cancer

Remya Prasannan , Karunakaran A. Kalesh , Muthu K. Shanmugam , Alamelu Nachiyappan
Biochemical Pharmacology 84 ( 10) 1268 -1276

97
2012