引用次数
引用: 5,699
H-指数: 42
I10-指数 : 99
出版物: 183
Docking Ligands into Flexible and Solvated Macromolecules. 8. Forming New Bonds – Challenges and Opportunities.
Pottel J , Patrascu Mb , Martins A , Moitessier N
ChemRxiv
2021
Design, synthesis and evaluation of antiestrogen and histone deacetylase inhibitor molecular hybrids.
Gleason JL. Mendoza-Sanchez R , Cotnoir-White D , Kulpa J , Jutras I
Bioorg Med Chem. 23 ( 24) 7597 -606
43
2015
1alpha,25-dihydroxyvitamin D3 agonist and histone deacetylase inhibitor bifunctional ligand discovery
James L Gleason , Nicolas Moitessier , Melanie Burger
McGill University
2011
Mutations in Dynamic Structural Elements Alter the Kinetics and Fidelity of the Multifunctional Class II Lanthipeptide Synthetase, HalM2.
Christopher J Thibodeaux , Nicolas Moitessier , Wanlei Wei , Yeganeh Habibi
Biochemistry 60 ( 5) 412 -430
1
2021
Regioselective acylation, alkylation, silylation and glycosylation of monosaccharides
Janice Lawandi , Sylvain Rocheleau , Nicolas Moitessier
Tetrahedron 72 ( 41) 6283 -6319
48
2016
Efficient Transition State Modeling Using Molecular Mechanics Force Fields for the Everyday Chemist
Joshua Pottel , Nicolas Moitessier
Reviews in Computational Chemistry, Volume 29 152 -185
2016
Tetrahydrofuran as a Scaffold for Peptidomimetics. Application to the Design and Synthesis of Conformationally Constrained Metalloproteinase Inhibitors
Stephen Hanessian , Nicolas Moitessier , Serge Wilmouth
Tetrahedron 56 ( 39) 7643 -7660
19
2000
Design, modeling and synthesis of functionalized paromamine analogs
Stephen Hanessian , Martin Tremblay , Alexander Kornienko , Nicolas Moitessier
Tetrahedron 57 ( 16) 3255 -3265
33
2001
Design and synthesis of MMP inhibitors using N -arylsulfonylaziridine hydroxamic acids as constrained scaffolds
Stephen Hanessian , Nicolas Moitessier , Louis-David Cantin
Tetrahedron 57 ( 32) 6885 -6900
18
2001
Atom Types Independent Molecular Mechanics Method for Predicting the Conformational Energy of Small Molecules
Zhaomin Liu , Stephen J. Barigye , Moeed Shahamat , Paul Labute
Journal of Chemical Information and Modeling 58 ( 1) 194 -205
18
2018
Predicting Positions of Bridging Water Molecules in Nucleic Acid-Ligand Complexes.
Wanlei Wei , Jiaying Luo , Jérôme Waldispühl , Nicolas Moitessier
Journal of Chemical Information and Modeling 59 ( 6) 2941 -2951
13
2019
Atom Type Independent Modeling of the Conformational Energy of Benzylic, Allylic, and Other Bonds Adjacent to Conjugated Systems.
Candide Champion , Stephen J. Barigye , Wanlei Wei , Zhaomin Liu
Journal of Chemical Information and Modeling 59 ( 11) 4750 -4763
1
2019
Torsional Energy Barriers of Biaryls Could Be Predicted by Electron Richness/Deficiency of Aromatic Rings; Advancement of Molecular Mechanics toward Atom-Type Independence
Wanlei Wei , Candide Champion , Zhaomin Liu , Stephen J. Barigye
Journal of Chemical Information and Modeling 59 ( 11) 4764 -4777
6
2019
Customizable Generation of Synthetically Accessible, Local Chemical Subspaces
Joshua Pottel , Nicolas Moitessier
Journal of Chemical Information and Modeling 57 ( 3) 454 -467
6
2017
Asymmetric dihydroxylation of d-xylose-derived allyl ethers
Nicolas Moitessier , Françoise Chrétien , Yves Chapleur
Tetrahedron-asymmetry 8 ( 17) 2889 -2892
15
1997
Toward a Computational Tool Predicting the Stereochemical Outcome of Asymmetric Reactions: Development and Application of a Rapid and Accurate Program Based on Organic Principles
Christopher R. Corbeil , Sabine Thielges , Jeremy A. Schwartzentruber , Nicolas Moitessier
Angewandte Chemie 47 ( 14) 2635 -2638
28
2008
Highly Regioselective Monoacylation of Unprotected Glucopyranoside using Transient Directing-Protecting Groups
Sylvain Rocheleau , Joshua Pottel , Igor Huskić , Nicolas Moitessier
European Journal of Organic Chemistry 2017 ( 3) 646 -656
8
2017
Solvent effect in diastereoselective intramolecular Diels–Alder reactions
Anna Tomberg , Stéphane De Cesco , Mitchell Huot , Nicolas Moitessier
Tetrahedron Letters 56 ( 49) 6852 -6856
5
2015
Integrated Synthetic, Biophysical, and Computational Investigations of Covalent Inhibitors of Prolyl Oligopeptidase and Fibroblast Activation Protein α.
Justin Di Trani , Caroline Dufresne , Alexander S. Wahba , Naëla Janmamode
Journal of Medicinal Chemistry 62 ( 17) 7874 -7884
12
2019
Modeling Reality for Optimal Docking of Small Molecules to Biological Targets
Christopher Corbeil , Eric Therrien , Nicolas Moitessier
Current Computer - Aided Drug Design 5 ( 4) 241 -263
15
2009
Chris Corbeil Joshua Pottel Eric Therrien Mihai Burai-Patrascu, Ph.D. Hanadi Sleiman zhaomin liu NATHANAEL WEILL Roxanne Kieltyka Wanlei Wei Chantal Autexier Jérôme Waldispühl Justin Di Trani Masad J. Damha Sandrine Gerber Katherine J Castor Christophe LEN Carlos Oliver Vladimir Reinharz Igor Huskic Roman Sarrazin-Gendron