Dewakar Sangaraju
机构: Genentech Inc, South Sanfrancisco & University of Minnesota, Minneapolis, USA
主页: linkedin.com
每年引用次数
引用次数
引用: 1,385
H-指数: 18
I10-指数 : 23
出版物: 46
Robust and Comprehensive Targeted Metabolomics Method for Quantification of 50 Different Primary, Secondary, and Sulfated Bile Acids in Multiple Biological Species (Human, Monkey, Rabbit, Dog, and Rat) and Matrices (Plasma and Urine) Using Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS) Analysis.
Brian Dean , Allan Jaochico , Xiaorong Liang , Yao Shi
Journal of the American Society for Mass Spectrometry
2021
5-Nitrothiazolylthiosemicarbazones: synthesis and antimycobacterial evaluation against tubercular and non-tubercular mycobacterial species.
Dhrmarajan Sriram , Perumal Yogeeswari , Palaniappan Senthilkumar , Dewakar Sangaraju
Journal of Enzyme Inhibition and Medicinal Chemistry 25 ( 1) 105 -110
5
2010
A multi-matrix HILIC-MS/MS method for the quantitation of endogenous small molecule neurological biomarker N-acetyl aspartic acid (NAA)
Dewakar Sangaraju , Sheerin K. Shahidi-Latham , Braydon L. Burgess , Brian Dean
Journal of Pharmaceutical and Biomedical Analysis 140 11 -19
15
2017
Isotope Dilution nanoLC/ESI+-HRMS3 Quantitation of Urinary N7-(1-Hydroxy-3-buten-2-yl) Guanine Adducts in Humans and Their Use as Biomarkers of Exposure to 1,3-Butadiene
Dewakar Sangaraju , Emily J. Boldry , Yesha M. Patel , Vernon Walker
Chemical Research in Toxicology 30 ( 2) 678 -688
5
2017
N6-(2-Deoxy-d-erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5-N-(2-hydroxy-3-buten-1-yl)-formamidopyrimidine Adducts of 1,3-Butadiene: Synthesis, Structural Identification, and Detection in Human Cells
Arnold S. Groehler , Dominic Najjar , Suresh S. Pujari , Dewakar Sangaraju
Chemical Research in Toxicology 31 ( 9) 885 -897
2
2018
Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP.
Yi Zhou , Mingjian Fei , Gu Zhang , Wei-Ching Liang
Immunity 52 ( 2) 357
169
2020
Comprehensive Evaluation of Bile Acid Homeostasis in Human Hepatocyte Co-Culture in the Presence of Troglitazone, Pioglitazone, and Acetylsalicylic Acid.
Jae H. Chang , Dewakar Sangaraju , Ning Liu , Allan Jaochico
Molecular Pharmaceutics 16 ( 10) 4230 -4240
2
2019
Synthesis and Antimycobacterial Evaluation of Novel Phthalazin-4-ylacetamides Against log- and Starved Phase Cultures
Dharmarajan Sriram , Perumal Yogeeswari , Palaniappan Senthilkumar , Dewakar Sangaraju
Chemical Biology & Drug Design 75 ( 4) 381 -391
20
2010
Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State
Anneleen Daemen , Bonnie Liu , Kyung Song , Mandy Kwong
Cell Metabolism 28 ( 3) 383 -399
57
2018
Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues
Lauren Lewis , Grace A. Chappell , Tetyana Kobets , Bridget E. O’Brian
Archives of Toxicology 93 ( 3) 791 -800
5
2019
Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide
José L. McFaline-Figueroa , Christian J. Braun , Monica Stanciu , Zachary D. Nagel
Cancer Research 75 ( 15) 3127 -3138
58
2015
Epigenetic Events Determine Tissue-Specific Toxicity of Inhalational Exposure to the Genotoxic Chemical 1,3-Butadiene in Male C57BL/6J Mice
Grace Chappell , Tetyana Kobets , Bridget O’Brien , Natalia Tretyakova
Toxicological Sciences 142 ( 2) 375 -384
20
2014
Cellular Repair of DNA-DNA Cross-Links Induced by 1,2,3,4-Diepoxybutane.
Lisa Chesner , Amanda Degner , Dewakar Sangaraju , Shira Yomtoubian
International Journal of Molecular Sciences 18 ( 5) 1086
4
2017
Bis-butanediol-mercapturic acid (bis-BDMA) as a urinary biomarker of metabolic activation of butadiene to its ultimate carcinogenic species
Srikanth Kotapati , Dewakar Sangaraju , Amanda Esades , Lance Hallberg
Carcinogenesis 35 ( 6) 1371 -1378
8
2014
A rapid derivatization based LC-MS/MS method for quantitation of short chain fatty acids in human plasma and urine.
Allan Jaochico , Dewakar Sangaraju , Sheerin K Shahidi-Latham
Bioanalysis 11 ( 8) 741 -753
4
2019
NanoLC/ESI+ HRMS3 Quantitation of DNA Adducts Induced by 1,3-Butadiene
Dewakar Sangaraju , Peter W. Villalta , Susith Wickramaratne , James Swenberg
Journal of the American Society for Mass Spectrometry 25 ( 7) 1124 -1135
22
2014
Erratum to: NanoLC/ESI+ HRMS3 Quantitation of DNA Adducts Induced by 1,3-Butadiene
Dewakar Sangaraju , Peter W. Villalta , Susith Wickramaratne , James Swenberg
Journal of the American Society for Mass Spectrometry 25 ( 9) 1674 -1674
2014
A Novel Depurination Methodology to Assess DNA Alkylation of Chloro-Bis-Seco-Cyclopropylbenzoindoles Allowed for Comparison of Minor-Groove Reactivity
Shuai Wang , Buyun Chen , Peter Dragovich , Thomas Pillow
Drug Metabolism and Disposition 47 ( 5) 547 -555
1
2019
Structure of the essential inner membrane lipopolysaccharide-PbgA complex.
Thomas Clairfeuille , Kerry R. Buchholz , Qingling Li , Erik Verschueren
Nature 584 ( 7821) 479 -483
21
2020
NanoHPLC-nanoESI +-MS/MS quantitation of Bis -N7-Guanine DNA-DNA cross-links in tissues of B6C3F1 mice exposed to subppm levels of 1,3-butadiene
Dewakar Sangaraju , Melissa Goggin , Vernon Walker , James Swenberg
Analytical Chemistry 84 ( 3) 1732 -1739
20
2012