Mutational analysis of the tumor suppressor gene BRG1 in human lung primary tumors by next-gen sequencing technology

S. Rodriguez-Nieto , O.A. Romero , P.P. Medina , M.A. Tortoledo
Ejc Supplements 6 ( 9) 117

2008
2O MET activation in lung cancer up-regulates PD-L1 expression independently of JAK-STAT pathway, promoting an immunosuppressive phenotype

M. Saigí , J.J. Alburquerque-Béjar , A. Mc Leer-Florin , C. Pereira
Journal of Thoracic Oncology 13 ( 4)

2018
MAX mutant small-cell lung cancers exhibit impaired activities of MGA-dependent noncanonical polycomb repressive complex

Paula Llabata , Manuel Torres-Diz , Antonio Gomez , Laureano Tomas-Daza
Proceedings of the National Academy of Sciences 118 ( 37) e2024824118 -e2024824118

10
2021
New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-β2

Beatriz Pérez-Benavente , Alihamze Fathinajafabadi , Lorena De la Fuente , Carolina Gandía
Genome Biology 23 ( 1) 252 -252

18
2022
New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-ß2

Beatriz Pérez-Benavente , Alihamze Fathinajafabadi , Carolina Gandía , Arantxa Martínez-Férriz
BioMed Central

2022
Unveiling the relationship between the SWI/SNF chromatin remodeling complex and noncoding RNAs

Paola Peinado Fernández , Isabel Fernández Coira , Eva E Rufino Palomares , Octavio A Romero
Cancer Research 76 ( 14_Supplement) 4479 -4479

2016
MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer

Juan J Alburquerque-Bejar , Pablo Navajas-Chocarro , Maria Saigi , Ana Ferrero-Andres
Cell Reports Medicine 4 ( 4)

5
2023
Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts.

Chiara Ambrogio , Francisco J Carmona , August Vidal , Mattia Falcone
Cancer Research 74 ( 21) 5978 -5988

22
2014
SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade

Octavio A Romero , Andrea Vilarrubi , Juan J Alburquerque-Bejar , Antonio Gomez
Nature communications 12 ( 1) 4319 -4319

32
2021
SWI/SNF inactivation vulnerability

Andrea Vilarrubi , Fernando Setien , Eva Pros , Pedro P Medina
Cancer Research 82 ( 12_Supplement) 3277 -3277

2022
MAX inactivation in small cell lung cancer disrupts the MYC-SWI/SNF programs and is synthetic lethal with BRG1

Manuel Torres-Diz , Octavio A Romero , Eva Pros , Suvi Savola
MOLECULAR CANCER RESEARCH 13

2015
Sensitization of retinoids and corticoids to epigenetic drugs in MYC-activated lung cancers by antitumor reprogramming

Octavio A Romero , S Verdura , M Torres-Diz , A Gomez
Oncogene 36 ( 9) 1287 -1296

5
2017
Epigenetic Events in Lung Cancer

Octavio A Romero , Montse Sanchez-Cespedes
Springer International Publishing 17 -31

2022
Expression inactivation of SMARCA4 by microRNAs in lung tumors

Isabel F Coira , Eva E Rufino-Palomares , Octavio A Romero , Paola Peinado
Human Molecular Genetics 24 ( 5) 1400 -1409

16
2015
The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells.

M. Carmen Lafita-Navarro , Judit Liaño-Pons , Andrea Quintanilla , Ignacio Varela
Journal of Biological Chemistry 295 ( 7) 2001 -2017

5
2020
Abstract A35: MAX inactivation in small cell lung cancer disrupts the MYC-SWI/SNF programs and is synthetic lethal with BRG1

Manuel Torres-Diz , Octavio A. Romero , Eva Pros , Suvi Savola
Molecular Cancer Research 13

2015
Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines.

Pedro P. Medina , Octavio A. Romero , Takashi Kohno , Luis M. Montuenga
Human Mutation 29 ( 5) 617 -622

267
2008
The tumour suppressor and chromatin‐remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer

Octavio A. Romero , Fernando Setien , Sam John , Pol Gimenez‐Xavier
Embo Molecular Medicine 4 ( 7) 603 -616

53
2012
MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1.

Octavio A. Romero , Manuel Torres-Diz , Eva Pros , Suvi Savola
Cancer Discovery 4 ( 3) 292 -303

109
2014
Comprehensive Analysis of SWI/SNF Inactivation in Lung Adenocarcinoma Cell Models.

Paola Peinado , Alvaro Andrades , Marta Cuadros , Maria Isabel Rodriguez
Cancers 12 ( 12) 3712

2020